Kfl00387_0030 (kfl00387_0030_v1.1)


Aliases : kfl00387_0030_v1.1

Description : (at3g06483 : 482.0) Pyruvate dehydrogenase kinase (PDK) specifically phosphorylates the E1α subunit of the pyruvate dehydrogenase complex (PDC) on a Ser residue using ATP as a phosphate donor. PDK is a unique type of protein kinase having a His-kinase-like sequence but Ser-kinase activity. Site-directed mutagenesis and structural analysis indicate that PDK belongs to the GHKL superfamily.; pyruvate dehydrogenase kinase (PDK); FUNCTIONS IN: ATP binding, pyruvate dehydrogenase (acetyl-transferring) kinase activity, histidine phosphotransfer kinase activity; INVOLVED IN: signal transduction, peptidyl-histidine phosphorylation, phosphorylation; LOCATED IN: mitochondrion; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Signal transduction histidine kinase, core (InterPro:IPR005467), Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, mitochondrial (InterPro:IPR018955), ATPase-like, ATP-binding domain (InterPro:IPR003594), Signal transduction histidine kinase-related protein, C-terminal (InterPro:IPR004358); Has 1925 Blast hits to 1799 proteins in 531 species: Archae - 0; Bacteria - 712; Metazoa - 467; Fungi - 468; Plants - 102; Viruses - 0; Other Eukaryotes - 176 (source: NCBI BLink). & (reliability: 964.0) & (original description: no original description)


Gene families : OG_42_0003838 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003838_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00387_0030
Cluster HCCA clusters: Cluster_93

Target Alias Description ECC score Gene Family Method Actions
Cre06.g278451 No alias pyruvate dehydrogenase kinase 0.04 Orthogroups_2024-Update
Solyc12g098930 No alias pyruvate dehydrogenase kinase (AHRD V3.3 *** AT3G06483.1) 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Predicted GO
MF GO:0004813 alanine-tRNA ligase activity IEP Predicted GO
CC GO:0005575 cellular_component IEP Predicted GO
CC GO:0005730 nucleolus IEP Predicted GO
CC GO:0005789 endoplasmic reticulum membrane IEP Predicted GO
BP GO:0006364 rRNA processing IEP Predicted GO
BP GO:0006418 tRNA aminoacylation for protein translation IEP Predicted GO
BP GO:0006419 alanyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006820 anion transport IEP Predicted GO
BP GO:0006855 drug transmembrane transport IEP Predicted GO
MF GO:0015238 drug transmembrane transporter activity IEP Predicted GO
MF GO:0015297 antiporter activity IEP Predicted GO
BP GO:0015893 drug transport IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
BP GO:0016072 rRNA metabolic process IEP Predicted GO
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Predicted GO
BP GO:0034470 ncRNA processing IEP Predicted GO
BP GO:0034660 ncRNA metabolic process IEP Predicted GO
BP GO:0043038 amino acid activation IEP Predicted GO
BP GO:0043039 tRNA aminoacylation IEP Predicted GO
CC GO:0043226 organelle IEP Predicted GO
CC GO:0043229 intracellular organelle IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044432 endoplasmic reticulum part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
InterPro domains Description Start Stop
IPR018955 BCDHK/PDK_N 33 195
IPR003594 HATPase_C 239 359
No external refs found!