Kfl00473_0050 (kfl00473_0050_v1.1)


Aliases : kfl00473_0050_v1.1

Description : (q9znx6|gsh1_medtr : 508.0) Glutamate--cysteine ligase, chloroplast precursor (EC 6.3.2.2) (Gamma-glutamylcysteine synthetase) (Gamma-ECS) (GCS) - Medicago truncatula (Barrel medic) & (at4g23100 : 497.0) Encodes the enzyme glutamate-cysteine ligase catalyzing the first, and rate-limiting, step of glutathione biosynthesis. Required for cell proliferation at the root tip. Involved in susceptibility to the bacterial pathogen Pseudomonas syringae. Mutants are phytoalexin defective.; glutamate-cysteine ligase (GSH1); CONTAINS InterPro DOMAIN/s: Glutamate--cysteine ligase, GCS2 (InterPro:IPR006336), Glutamate--cysteine ligase, plant (InterPro:IPR011556). & (reliability: 994.0) & (original description: no original description)


Gene families : OG_42_0006101 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0006101_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00473_0050
Cluster HCCA clusters: Cluster_2


Type GO Term Name Evidence Source
MF GO:0004357 glutamate-cysteine ligase activity IEA InterProScan predictions
BP GO:0042398 cellular modified amino acid biosynthetic process IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0003848 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity IEP Predicted GO
MF GO:0004177 aminopeptidase activity IEP Predicted GO
CC GO:0005744 TIM23 mitochondrial import inner membrane translocase complex IEP Predicted GO
BP GO:0006575 cellular modified amino acid metabolic process IEP Predicted GO
BP GO:0006665 sphingolipid metabolic process IEP Predicted GO
BP GO:0006672 ceramide metabolic process IEP Predicted GO
BP GO:0006760 folic acid-containing compound metabolic process IEP Predicted GO
BP GO:0006839 mitochondrial transport IEP Predicted GO
MF GO:0008641 ubiquitin-like modifier activating enzyme activity IEP Predicted GO
BP GO:0009396 folic acid-containing compound biosynthetic process IEP Predicted GO
BP GO:0010035 response to inorganic substance IEP Predicted GO
BP GO:0010038 response to metal ion IEP Predicted GO
MF GO:0016603 glutaminyl-peptide cyclotransferase activity IEP Predicted GO
MF GO:0016746 transferase activity, transferring acyl groups IEP Predicted GO
MF GO:0016755 transferase activity, transferring amino-acyl groups IEP Predicted GO
MF GO:0016774 phosphotransferase activity, carboxyl group as acceptor IEP Predicted GO
MF GO:0016778 diphosphotransferase activity IEP Predicted GO
MF GO:0016854 racemase and epimerase activity IEP Predicted GO
MF GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives IEP Predicted GO
MF GO:0016877 ligase activity, forming carbon-sulfur bonds IEP Predicted GO
BP GO:0017038 protein import IEP Predicted GO
BP GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase IEP Predicted GO
BP GO:0018193 peptidyl-amino acid modification IEP Predicted GO
BP GO:0018199 peptidyl-glutamine modification IEP Predicted GO
BP GO:0030150 protein import into mitochondrial matrix IEP Predicted GO
BP GO:0042221 response to chemical IEP Predicted GO
BP GO:0042558 pteridine-containing compound metabolic process IEP Predicted GO
BP GO:0042559 pteridine-containing compound biosynthetic process IEP Predicted GO
BP GO:0043603 cellular amide metabolic process IEP Predicted GO
BP GO:0044255 cellular lipid metabolic process IEP Predicted GO
CC GO:0044455 mitochondrial membrane part IEP Predicted GO
BP GO:0044743 protein transmembrane import into intracellular organelle IEP Predicted GO
BP GO:0046834 lipid phosphorylation IEP Predicted GO
BP GO:0046854 phosphatidylinositol phosphorylation IEP Predicted GO
MF GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer IEP Predicted GO
BP GO:0065002 intracellular protein transmembrane transport IEP Predicted GO
BP GO:0070585 protein localization to mitochondrion IEP Predicted GO
BP GO:0071806 protein transmembrane transport IEP Predicted GO
BP GO:0072655 establishment of protein localization to mitochondrion IEP Predicted GO
CC GO:0098800 inner mitochondrial membrane protein complex IEP Predicted GO
BP GO:1990542 mitochondrial transmembrane transport IEP Predicted GO
InterPro domains Description Start Stop
IPR006336 GCS2 59 360
No external refs found!