Kfl00489_0040 (kfl00489_0040_v1.1)

Aliases : kfl00489_0040_v1.1

Description : (at2g21790 : 1267.0) encodes large subunit of ribonucleotide reductase involved in the production of deoxyribonucleoside triphosphates (dNTPs) for DNA replication and repair; ribonucleotide reductase 1 (RNR1); FUNCTIONS IN: ribonucleoside-diphosphate reductase activity, ATP binding; INVOLVED IN: response to cadmium ion, DNA replication, deoxyribonucleoside triphosphate biosynthetic process; LOCATED IN: ribonucleoside-diphosphate reductase complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ribonucleotide reductase large subunit, N-terminal (InterPro:IPR013509), Ribonucleoside-diphosphate reductase, alpha subunit (InterPro:IPR013346), ATP-cone (InterPro:IPR005144), Ribonucleotide reductase large subunit, C-terminal (InterPro:IPR000788), Ribonucleotide reductase R1 subunit, N-terminal (InterPro:IPR008926); Has 15326 Blast hits to 14804 proteins in 2790 species: Archae - 206; Bacteria - 6388; Metazoa - 177; Fungi - 215; Plants - 88; Viruses - 606; Other Eukaryotes - 7646 (source: NCBI BLink). & (reliability: 2534.0) & (original description: no original description)

Gene families : OG_42_0002341 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002341_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00489_0040
Cluster	HCCA clusters: Cluster_38

Target	Alias	Description	ECC score	Gene Family Method
At2g21790	No alias	Ribonucleoside-diphosphate reductase large subunit...	0.03	Orthogroups_2024-Update
Brara.F03660.1	No alias	large subunit of ribonucleoside-diphosphate reductase...	0.02	Orthogroups_2024-Update
Cre12.g492950	No alias	ribonucleotide reductase 1	0.03	Orthogroups_2024-Update
GRMZM2G304362	No alias	ribonucleotide reductase 1	0.01	Orthogroups_2024-Update
Glyma.04G217300	No alias	ribonucleotide reductase 1	0.06	Orthogroups_2024-Update
Glyma.05G186900	No alias	ribonucleotide reductase 1	0.08	Orthogroups_2024-Update
Glyma.06G148500	No alias	ribonucleotide reductase 1	0.05	Orthogroups_2024-Update
HORVU7Hr1G027430.1	No alias	large subunit of ribonucleoside-diphosphate reductase...	0.02	Orthogroups_2024-Update
MA_158556g0010	No alias	(at2g21790 : 1386.0) encodes large subunit of...	0.05	Orthogroups_2024-Update
PSME_00043454-RA	No alias	(at2g21790 : 625.0) encodes large subunit of...	0.01	Orthogroups_2024-Update
Solyc04g012060	No alias	Ribonucleoside-diphosphate reductase (AHRD V3.3 *** K4BPQ8_SOLLC)	0.07	Orthogroups_2024-Update
Solyc04g051350	No alias	Ribonucleoside-diphosphate reductase (AHRD V3.3 *** K4BS95_SOLLC)	0.01	Orthogroups_2024-Update
Sopen04g006180	No alias	Ribonucleotide reductase, barrel domain	0.02	Orthogroups_2024-Update
evm.model.contig_2144.6	No alias	(at2g21790 : 1100.0) encodes large subunit of...	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006260	DNA replication	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	None	Extended
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	InterProScan predictions
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000723	telomere maintenance	IEP	Predicted GO
BP	GO:0000724	double-strand break repair via homologous recombination	IEP	Predicted GO
BP	GO:0000725	recombinational repair	IEP	Predicted GO
CC	GO:0000781	chromosome, telomeric region	IEP	Predicted GO
CC	GO:0000784	nuclear chromosome, telomeric region	IEP	Predicted GO
CC	GO:0000796	condensin complex	IEP	Predicted GO
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003677	DNA binding	IEP	Predicted GO
MF	GO:0003678	DNA helicase activity	IEP	Predicted GO
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Predicted GO
MF	GO:0003896	DNA primase activity	IEP	Predicted GO
MF	GO:0004386	helicase activity	IEP	Predicted GO
CC	GO:0005694	chromosome	IEP	Predicted GO
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Predicted GO
BP	GO:0006275	regulation of DNA replication	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006298	mismatch repair	IEP	Predicted GO
BP	GO:0006302	double-strand break repair	IEP	Predicted GO
BP	GO:0006323	DNA packaging	IEP	Predicted GO
BP	GO:0006333	chromatin assembly or disassembly	IEP	Predicted GO
BP	GO:0006401	RNA catabolic process	IEP	Predicted GO
BP	GO:0006950	response to stress	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
BP	GO:0006996	organelle organization	IEP	Predicted GO
BP	GO:0007076	mitotic chromosome condensation	IEP	Predicted GO
BP	GO:0016043	cellular component organization	IEP	Predicted GO
MF	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	IEP	Predicted GO
MF	GO:0016779	nucleotidyltransferase activity	IEP	Predicted GO
MF	GO:0019207	kinase regulator activity	IEP	Predicted GO
MF	GO:0019887	protein kinase regulator activity	IEP	Predicted GO
BP	GO:0030261	chromosome condensation	IEP	Predicted GO
CC	GO:0030915	Smc5-Smc6 complex	IEP	Predicted GO
MF	GO:0030983	mismatched DNA binding	IEP	Predicted GO
BP	GO:0032200	telomere organization	IEP	Predicted GO
CC	GO:0032299	ribonuclease H2 complex	IEP	Predicted GO
BP	GO:0033554	cellular response to stress	IEP	Predicted GO
MF	GO:0034061	DNA polymerase activity	IEP	Predicted GO
MF	GO:0043138	3'-5' DNA helicase activity	IEP	Predicted GO
MF	GO:0043140	ATP-dependent 3'-5' DNA helicase activity	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044427	chromosomal part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0050896	response to stimulus	IEP	Predicted GO
BP	GO:0051052	regulation of DNA metabolic process	IEP	Predicted GO
BP	GO:0051276	chromosome organization	IEP	Predicted GO
BP	GO:0051716	cellular response to stimulus	IEP	Predicted GO
BP	GO:0060249	anatomical structure homeostasis	IEP	Predicted GO
BP	GO:0071103	DNA conformation change	IEP	Predicted GO
BP	GO:0071840	cellular component organization or biogenesis	IEP	Predicted GO
CC	GO:0098687	chromosomal region	IEP	Predicted GO
CC	GO:0106068	SUMO ligase complex	IEP	Predicted GO
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Predicted GO
BP	GO:1903047	mitotic cell cycle process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR013509	RNR_lsu_N	142	212
IPR000788	RNR_lg_C	216	757
IPR005144	ATP-cone_dom	1	89

External Links

No external refs found!

Kfl00489_0040 (kfl00489_0040_v1.1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation