Kfl00501_0060 (kfl00501_0060_v1.1,...)

Aliases : kfl00501_0060_v1.1, kfl00501_0060_v1.1

Description : (at2g25940 : 533.0) Encodes a vacuolar processing enzyme belonging to a novel group of cysteine proteinases that is expressed in vegetative organs and is upregulated in association with various types of cell death and under stressed conditions.; alpha-vacuolar processing enzyme (ALPHA-VPE); FUNCTIONS IN: cysteine-type endopeptidase activity; INVOLVED IN: proteolysis, vacuolar protein processing; LOCATED IN: endomembrane system; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Peptidase C13, legumain (InterPro:IPR001096); BEST Arabidopsis thaliana protein match is: gamma vacuolar processing enzyme (TAIR:AT4G32940.1); Has 793 Blast hits to 791 proteins in 239 species: Archae - 4; Bacteria - 12; Metazoa - 278; Fungi - 115; Plants - 259; Viruses - 0; Other Eukaryotes - 125 (source: NCBI BLink). & (p49047|vpea_arath : 533.0) Vacuolar-processing enzyme alpha-isozyme precursor (EC 3.4.22.-) (Alpha-VPE) - Arabidopsis thaliana (Mouse-ear cress) & (reliability: 1040.0) & (original description: no original description)

Gene families : OG_42_0000853 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000853_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00501_0060
Cluster	HCCA clusters: Cluster_2

Target	Alias	Description	ECC score	Gene Family Method
A4A49_62240	No alias	vacuolar-processing enzyme	0.03	Orthogroups_2024-Update
PSME_00030837-RA	No alias	(p49043\|vpe_citsi : 631.0) Vacuolar-processing enzyme...	0.02	Orthogroups_2024-Update
Potri.001G119832	No alias	beta vacuolar processing enzyme	0.03	Orthogroups_2024-Update
Sobic.006G161300.1	No alias	programmed cell death cysteine proteinase *(VPE) &...	0.02	Orthogroups_2024-Update
Solyc12g095910	No alias	cysteine protease	0.03	Orthogroups_2024-Update
Sopen12g031810	No alias	Peptidase C13 family	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
BP	GO:0006508	proteolysis	IEA	InterProScan predictions
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	IEA	InterProScan predictions
MF	GO:0016787	hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0004197	cysteine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0005337	nucleoside transmembrane transporter activity	IEP	Predicted GO
BP	GO:0005975	carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
BP	GO:0006665	sphingolipid metabolic process	IEP	Predicted GO
BP	GO:0006672	ceramide metabolic process	IEP	Predicted GO
BP	GO:0006888	ER to Golgi vesicle-mediated transport	IEP	Predicted GO
MF	GO:0008234	cysteine-type peptidase activity	IEP	Predicted GO
BP	GO:0015858	nucleoside transport	IEP	Predicted GO
BP	GO:0015931	nucleobase-containing compound transport	IEP	Predicted GO
MF	GO:0015932	nucleobase-containing compound transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient	IEP	Predicted GO
BP	GO:0015991	ATP hydrolysis coupled proton transport	IEP	Predicted GO
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	IEP	Predicted GO
MF	GO:0016780	phosphotransferase activity, for other substituted phosphate groups	IEP	Predicted GO
MF	GO:0016853	isomerase activity	IEP	Predicted GO
MF	GO:0016868	intramolecular transferase activity, phosphotransferases	IEP	Predicted GO
MF	GO:0019842	vitamin binding	IEP	Predicted GO
MF	GO:0020037	heme binding	IEP	Predicted GO
CC	GO:0030120	vesicle coat	IEP	Predicted GO
CC	GO:0030127	COPII vesicle coat	IEP	Predicted GO
MF	GO:0030976	thiamine pyrophosphate binding	IEP	Predicted GO
MF	GO:0043169	cation binding	IEP	Predicted GO
BP	GO:0044255	cellular lipid metabolic process	IEP	Predicted GO
CC	GO:0044425	membrane part	IEP	Predicted GO
MF	GO:0046872	metal ion binding	IEP	Predicted GO
MF	GO:0046906	tetrapyrrole binding	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
MF	GO:0050662	coenzyme binding	IEP	Predicted GO
BP	GO:0050790	regulation of catalytic activity	IEP	Predicted GO
BP	GO:0065009	regulation of molecular function	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
CC	GO:0071203	WASH complex	IEP	Predicted GO
BP	GO:0090662	ATP hydrolysis coupled transmembrane transport	IEP	Predicted GO
BP	GO:0099131	ATP hydrolysis coupled ion transmembrane transport	IEP	Predicted GO
BP	GO:0099132	ATP hydrolysis coupled cation transmembrane transport	IEP	Predicted GO
BP	GO:1901264	carbohydrate derivative transport	IEP	Predicted GO
MF	GO:1901505	carbohydrate derivative transmembrane transporter activity	IEP	Predicted GO
BP	GO:1901642	nucleoside transmembrane transport	IEP	Predicted GO
MF	GO:1901681	sulfur compound binding	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001096	Peptidase_C13	46	317

External Links

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Kfl00501_0060 (kfl00501_0060_v1.1,...)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation