Kfl00508_0100 (kfl00508_0100_v1.1)

Aliases : kfl00508_0100_v1.1

Description : (at4g03240 : 123.0) Encodes AtFH, a frataxin homolog. Frataxin is required for the biogenesis of mitochondria in different organisms. AtFH knock-out mutants are lethal. Required for full activity of mitochondrial Fe-S proteins. Deficiency of AtFH induces oxidative stress.; frataxin homolog (FH); CONTAINS InterPro DOMAIN/s: Frataxin (InterPro:IPR017789), Frataxin conserved site (InterPro:IPR020895), Frataxin-like (InterPro:IPR002908); Has 1148 Blast hits to 1148 proteins in 551 species: Archae - 0; Bacteria - 783; Metazoa - 128; Fungi - 127; Plants - 48; Viruses - 0; Other Eukaryotes - 62 (source: NCBI BLink). & (reliability: 246.0) & (original description: no original description)

Gene families : OG_42_0007592 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0007592_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00508_0100
Cluster	HCCA clusters: Cluster_58

Target	Alias	Description	ECC score	Gene Family Method	Actions
Bradi2g51900	No alias	frataxin homolog	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005506	iron ion binding	None	Extended
BP	GO:0006790	sulfur compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008199	ferric iron binding	IEA	InterProScan predictions
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
BP	GO:0016226	iron-sulfur cluster assembly	IEA	InterProScan predictions
BP	GO:0022607	cellular component assembly	None	Extended
BP	GO:0031163	metallo-sulfur cluster assembly	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0051186	cofactor metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0004527	exonuclease activity	IEP	Predicted GO
MF	GO:0004888	transmembrane signaling receptor activity	IEP	Predicted GO
MF	GO:0004970	ionotropic glutamate receptor activity	IEP	Predicted GO
MF	GO:0005230	extracellular ligand-gated ion channel activity	IEP	Predicted GO
MF	GO:0005509	calcium ion binding	IEP	Predicted GO
MF	GO:0005543	phospholipid binding	IEP	Predicted GO
MF	GO:0005544	calcium-dependent phospholipid binding	IEP	Predicted GO
MF	GO:0008066	glutamate receptor activity	IEP	Predicted GO
MF	GO:0008289	lipid binding	IEP	Predicted GO
MF	GO:0008408	3'-5' exonuclease activity	IEP	Predicted GO
MF	GO:0015276	ligand-gated ion channel activity	IEP	Predicted GO
MF	GO:0022824	transmitter-gated ion channel activity	IEP	Predicted GO
MF	GO:0022834	ligand-gated channel activity	IEP	Predicted GO
MF	GO:0022835	transmitter-gated channel activity	IEP	Predicted GO
MF	GO:0022836	gated channel activity	IEP	Predicted GO
MF	GO:0022839	ion gated channel activity	IEP	Predicted GO
MF	GO:0030594	neurotransmitter receptor activity	IEP	Predicted GO
MF	GO:0038023	signaling receptor activity	IEP	Predicted GO
MF	GO:0060089	molecular transducer activity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002908	Frataxin/CyaY	128	231

External Links

No external refs found!

Kfl00508_0100 (kfl00508_0100_v1.1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation