Kfl00523_0050 (kfl00523_0050_v1.1)

Aliases : kfl00523_0050_v1.1

Description : (at3g24320 : 539.0) Promotes re-arrangements of mitochondrial genome. Mutations affects mitochondrial gene expression, and impairs mitochondrial function. Dual targeting of the protein to mitochondria and chloroplasts caused by alternative translation initiation.; MUTL protein homolog 1 (MSH1); FUNCTIONS IN: damaged DNA binding, mismatched DNA binding, catalytic activity, ATP binding, nuclease activity; INVOLVED IN: mismatch repair, mitochondrial genome maintenance, mitochondrial DNA metabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Serine/cysteine peptidase, trypsin-like (InterPro:IPR009003), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), Excinuclease ABC, C subunit, N-terminal (InterPro:IPR000305), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695); BEST Arabidopsis thaliana protein match is: MUTS homolog 6 (TAIR:AT4G02070.2); Has 14048 Blast hits to 12806 proteins in 2713 species: Archae - 218; Bacteria - 10179; Metazoa - 621; Fungi - 751; Plants - 393; Viruses - 3; Other Eukaryotes - 1883 (source: NCBI BLink). & (reliability: 1078.0) & (original description: no original description)

Gene families : OG_42_0004403 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004403_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00523_0050
Cluster	HCCA clusters: Cluster_1

Target	Alias	Description	ECC score	Gene Family Method	Actions
Mp7g19320.1	No alias	MSH1 genome stability maintenance factor	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	InterProScan predictions
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0001510	RNA methylation	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003747	translation release factor activity	IEP	Predicted GO
MF	GO:0004180	carboxypeptidase activity	IEP	Predicted GO
MF	GO:0004185	serine-type carboxypeptidase activity	IEP	Predicted GO
MF	GO:0004435	phosphatidylinositol phospholipase C activity	IEP	Predicted GO
MF	GO:0004620	phospholipase activity	IEP	Predicted GO
MF	GO:0004629	phospholipase C activity	IEP	Predicted GO
MF	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity	IEP	Predicted GO
MF	GO:0004852	uroporphyrinogen-III synthase activity	IEP	Predicted GO
BP	GO:0006415	translational termination	IEP	Predicted GO
BP	GO:0006486	protein glycosylation	IEP	Predicted GO
BP	GO:0006487	protein N-linked glycosylation	IEP	Predicted GO
BP	GO:0006497	protein lipidation	IEP	Predicted GO
BP	GO:0006505	GPI anchor metabolic process	IEP	Predicted GO
BP	GO:0006506	GPI anchor biosynthetic process	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
BP	GO:0006661	phosphatidylinositol biosynthetic process	IEP	Predicted GO
MF	GO:0008079	translation termination factor activity	IEP	Predicted GO
MF	GO:0008092	cytoskeletal protein binding	IEP	Predicted GO
MF	GO:0008170	N-methyltransferase activity	IEP	Predicted GO
MF	GO:0008175	tRNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008194	UDP-glycosyltransferase activity	IEP	Predicted GO
MF	GO:0008375	acetylglucosaminyltransferase activity	IEP	Predicted GO
MF	GO:0015631	tubulin binding	IEP	Predicted GO
MF	GO:0016298	lipase activity	IEP	Predicted GO
MF	GO:0016423	tRNA (guanine) methyltransferase activity	IEP	Predicted GO
BP	GO:0016556	mRNA modification	IEP	Predicted GO
MF	GO:0016757	transferase activity, transferring glycosyl groups	IEP	Predicted GO
MF	GO:0016758	transferase activity, transferring hexosyl groups	IEP	Predicted GO
MF	GO:0017056	structural constituent of nuclear pore	IEP	Predicted GO
MF	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity	IEP	Predicted GO
BP	GO:0022411	cellular component disassembly	IEP	Predicted GO
MF	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity	IEP	Predicted GO
BP	GO:0032984	protein-containing complex disassembly	IEP	Predicted GO
MF	GO:0043015	gamma-tubulin binding	IEP	Predicted GO
BP	GO:0043413	macromolecule glycosylation	IEP	Predicted GO
BP	GO:0043624	cellular protein complex disassembly	IEP	Predicted GO
BP	GO:0046474	glycerophospholipid biosynthetic process	IEP	Predicted GO
MF	GO:0070008	serine-type exopeptidase activity	IEP	Predicted GO
BP	GO:0080009	mRNA methylation	IEP	Predicted GO
MF	GO:0140103	catalytic activity, acting on a glycoprotein	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000432	DNA_mismatch_repair_MutS_C	933	1042
IPR000432	DNA_mismatch_repair_MutS_C	832	928
IPR007695	DNA_mismatch_repair_MutS-lik_N	159	229

External Links

No external refs found!

Kfl00523_0050 (kfl00523_0050_v1.1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation