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  5. Kfl00533_0100

Kfl00533_0100 (kfl00533_0100_v1.1)


Aliases : kfl00533_0100_v1.1

Description : (p31251|ube12_wheat : 672.0) Ubiquitin-activating enzyme E1 2 - Triticum aestivum (Wheat) & (at5g06460 : 654.0) Encodes a ubiquitin-activating enzyme (E1), involved in the first step in conjugating multiple ubiquitins to proteins targeted for degradation. Gene is expressed in most tissues examined.; ubiquitin activating enzyme 2 (UBA 2); FUNCTIONS IN: ubiquitin-protein ligase activity, ubiquitin activating enzyme activity; INVOLVED IN: protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-activating enzyme, E1, active site (InterPro:IPR018074), Ubiquitin-activating enzyme, E1 (InterPro:IPR018075), Ubiquitin-activating enzyme e1, C-terminal (InterPro:IPR018965), Ubiquitin-activating enzyme repeat (InterPro:IPR000127), Ubiquitin-activating enzyme (InterPro:IPR019572), UBA/THIF-type NAD/FAD binding fold (InterPro:IPR000594), Molybdenum cofactor biosynthesis, MoeB (InterPro:IPR009036), NAD(P)-binding domain (InterPro:IPR016040), Ubiquitin-activating enzyme, E1-like (InterPro:IPR000011); BEST Arabidopsis thaliana protein match is: ubiquitin-activating enzyme 1 (TAIR:AT2G30110.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 1308.0) & (original description: no original description)


Gene families : OG_42_0001467 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001467_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00533_0100
Cluster HCCA clusters: Cluster_108

Target Alias Description ECC score Gene Family Method Actions
MA_10436758g0010 No alias (at2g30110 : 244.0) Encodes a ubiquitin-activating... 0.02 Orthogroups_2024-Update
MA_107903g0010 No alias (p31251|ube12_wheat : 1518.0) Ubiquitin-activating... 0.01 Orthogroups_2024-Update
PSME_00041857-RA No alias (p31251|ube12_wheat : 1366.0) Ubiquitin-activating... 0.02 Orthogroups_2024-Update
Pp1s160_156V6 No alias poly + rna transport protein 0.02 Orthogroups_2024-Update
Sobic.002G428800.1 No alias E1 ubiquitin-activating enzyme 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0008641 ubiquitin-like modifier activating enzyme activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0003688 DNA replication origin binding IEP Predicted GO
MF GO:0003690 double-stranded DNA binding IEP Predicted GO
MF GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity IEP Predicted GO
MF GO:0003997 acyl-CoA oxidase activity IEP Predicted GO
MF GO:0004784 superoxide dismutase activity IEP Predicted GO
CC GO:0005777 peroxisome IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006629 lipid metabolic process IEP Predicted GO
BP GO:0006631 fatty acid metabolic process IEP Predicted GO
BP GO:0006635 fatty acid beta-oxidation IEP Predicted GO
BP GO:0006801 superoxide metabolic process IEP Predicted GO
BP GO:0006888 ER to Golgi vesicle-mediated transport IEP Predicted GO
BP GO:0007275 multicellular organism development IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0008483 transaminase activity IEP Predicted GO
BP GO:0009062 fatty acid catabolic process IEP Predicted GO
BP GO:0016042 lipid catabolic process IEP Predicted GO
BP GO:0016054 organic acid catabolic process IEP Predicted GO
MF GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor IEP Predicted GO
MF GO:0016721 oxidoreductase activity, acting on superoxide radicals as acceptor IEP Predicted GO
MF GO:0016769 transferase activity, transferring nitrogenous groups IEP Predicted GO
BP GO:0019395 fatty acid oxidation IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
MF GO:0019842 vitamin binding IEP Predicted GO
CC GO:0030120 vesicle coat IEP Predicted GO
CC GO:0030127 COPII vesicle coat IEP Predicted GO
MF GO:0030170 pyridoxal phosphate binding IEP Predicted GO
BP GO:0032501 multicellular organismal process IEP Predicted GO
BP GO:0032502 developmental process IEP Predicted GO
BP GO:0032787 monocarboxylic acid metabolic process IEP Predicted GO
BP GO:0034440 lipid oxidation IEP Predicted GO
CC GO:0042579 microbody IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
MF GO:0043565 sequence-specific DNA binding IEP Predicted GO
BP GO:0044242 cellular lipid catabolic process IEP Predicted GO
BP GO:0044248 cellular catabolic process IEP Predicted GO
BP GO:0044255 cellular lipid metabolic process IEP Predicted GO
BP GO:0046395 carboxylic acid catabolic process IEP Predicted GO
MF GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer IEP Predicted GO
BP GO:0048856 anatomical structure development IEP Predicted GO
MF GO:0050662 coenzyme binding IEP Predicted GO
MF GO:0070279 vitamin B6 binding IEP Predicted GO
BP GO:0072329 monocarboxylic acid catabolic process IEP Predicted GO
BP GO:0072593 reactive oxygen species metabolic process IEP Predicted GO
MF GO:0098599 palmitoyl hydrolase activity IEP Predicted GO
MF GO:1990837 sequence-specific double-stranded DNA binding IEP Predicted GO
InterPro domains Description Start Stop
IPR000594 ThiF_NAD_FAD-bd 15 417
IPR032420 E1_4HB 266 310
IPR018965 Ub-activating_enz_E1_C 950 1043
IPR032418 E1_FCCH 195 261
IPR019572 UBA_E1_Cys 617 874
IPR000594 ThiF_NAD_FAD-bd 429 933
No external refs found!