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- Kfl00544_0080
Kfl00544_0080 (kfl00544_0080_v1.1)
Aliases : kfl00544_0080_v1.1
Description : (at5g39040 : 572.0) Encodes a member of TAP subfamily of ABC transporters that is located in the vacuole. Mutants are hypersensitive to aluminum and the gene product may be important for intracellular movement of some substrate, possibly chelated Al, as part of a mechanism of aluminum sequestration.; transporter associated with antigen processing protein 2 (TAP2); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances, transporter activity; INVOLVED IN: response to aluminum ion; LOCATED IN: vacuolar membrane, plasma membrane, vacuole, plant-type vacuole; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: P-glycoprotein 11 (TAIR:AT1G02520.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (q6yuu5|mdr_orysa : 297.0) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 1144.0) & (original description: no original description)
Expression Profile
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
| Type | Description | Actions |
| Neighborhood | Klebsormidium release: Kfl00544_0080 | |
| Cluster | HCCA clusters: Cluster_15 | |
Expression Context Conservation (ECC)
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
| Solyc03g114950 | No alias | No description available | 0.01 | Orthogroups_2024-Update | |
| Sopen03g034030 | No alias | ABC transporter transmembrane region | 0.02 | Orthogroups_2024-Update | |
Functional Annotation
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0000166 | nucleotide binding | None | Extended |
| MF | GO:0003674 | molecular_function | None | Extended |
| MF | GO:0003824 | catalytic activity | None | Extended |
| MF | GO:0005215 | transporter activity | None | Extended |
| MF | GO:0005488 | binding | None | Extended |
| MF | GO:0005524 | ATP binding | IEA | InterProScan predictions |
| CC | GO:0005575 | cellular_component | None | Extended |
| BP | GO:0006810 | transport | None | Extended |
| MF | GO:0008144 | drug binding | None | Extended |
| BP | GO:0008150 | biological_process | None | Extended |
| MF | GO:0015399 | primary active transmembrane transporter activity | None | Extended |
| MF | GO:0015405 | P-P-bond-hydrolysis-driven transmembrane transporter activity | None | Extended |
| CC | GO:0016021 | integral component of membrane | IEA | InterProScan predictions |
| MF | GO:0016462 | pyrophosphatase activity | None | Extended |
| MF | GO:0016787 | hydrolase activity | None | Extended |
| MF | GO:0016817 | hydrolase activity, acting on acid anhydrides | None | Extended |
| MF | GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | None | Extended |
| MF | GO:0016887 | ATPase activity | IEA | InterProScan predictions |
| MF | GO:0017076 | purine nucleotide binding | None | Extended |
| MF | GO:0017111 | nucleoside-triphosphatase activity | None | Extended |
| MF | GO:0022804 | active transmembrane transporter activity | None | Extended |
| MF | GO:0022857 | transmembrane transporter activity | None | Extended |
| MF | GO:0030554 | adenyl nucleotide binding | None | Extended |
| CC | GO:0031224 | intrinsic component of membrane | None | Extended |
| MF | GO:0032553 | ribonucleotide binding | None | Extended |
| MF | GO:0032555 | purine ribonucleotide binding | None | Extended |
| MF | GO:0032559 | adenyl ribonucleotide binding | None | Extended |
| MF | GO:0035639 | purine ribonucleoside triphosphate binding | None | Extended |
| MF | GO:0036094 | small molecule binding | None | Extended |
| MF | GO:0042623 | ATPase activity, coupled | None | Extended |
| MF | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | IEA | InterProScan predictions |
| MF | GO:0043167 | ion binding | None | Extended |
| MF | GO:0043168 | anion binding | None | Extended |
| MF | GO:0043492 | ATPase activity, coupled to movement of substances | None | Extended |
| CC | GO:0044425 | membrane part | None | Extended |
| BP | GO:0051179 | localization | None | Extended |
| BP | GO:0051234 | establishment of localization | None | Extended |
| BP | GO:0055085 | transmembrane transport | IEA | InterProScan predictions |
| MF | GO:0097159 | organic cyclic compound binding | None | Extended |
| MF | GO:0097367 | carbohydrate derivative binding | None | Extended |
| MF | GO:1901265 | nucleoside phosphate binding | None | Extended |
| MF | GO:1901363 | heterocyclic compound binding | None | Extended |
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0001871 | pattern binding | IEP | Predicted GO |
| MF | GO:0003688 | DNA replication origin binding | IEP | Predicted GO |
| MF | GO:0004133 | glycogen debranching enzyme activity | IEP | Predicted GO |
| MF | GO:0004134 | 4-alpha-glucanotransferase activity | IEP | Predicted GO |
| MF | GO:0004743 | pyruvate kinase activity | IEP | Predicted GO |
| MF | GO:0005092 | GDP-dissociation inhibitor activity | IEP | Predicted GO |
| BP | GO:0005975 | carbohydrate metabolic process | IEP | Predicted GO |
| BP | GO:0007264 | small GTPase mediated signal transduction | IEP | Predicted GO |
| BP | GO:0008152 | metabolic process | IEP | Predicted GO |
| MF | GO:0010277 | chlorophyllide a oxygenase [overall] activity | IEP | Predicted GO |
| MF | GO:0016491 | oxidoreductase activity | IEP | Predicted GO |
| MF | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | IEP | Predicted GO |
| MF | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | IEP | Predicted GO |
| MF | GO:0016703 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) | IEP | Predicted GO |
| MF | GO:0019842 | vitamin binding | IEP | Predicted GO |
| MF | GO:0030151 | molybdenum ion binding | IEP | Predicted GO |
| MF | GO:0030170 | pyridoxal phosphate binding | IEP | Predicted GO |
| MF | GO:0030246 | carbohydrate binding | IEP | Predicted GO |
| MF | GO:0030247 | polysaccharide binding | IEP | Predicted GO |
| MF | GO:0030695 | GTPase regulator activity | IEP | Predicted GO |
| MF | GO:0030955 | potassium ion binding | IEP | Predicted GO |
| MF | GO:0031420 | alkali metal ion binding | IEP | Predicted GO |
| MF | GO:0043565 | sequence-specific DNA binding | IEP | Predicted GO |
| MF | GO:0051213 | dioxygenase activity | IEP | Predicted GO |
| MF | GO:0051536 | iron-sulfur cluster binding | IEP | Predicted GO |
| MF | GO:0051537 | 2 iron, 2 sulfur cluster binding | IEP | Predicted GO |
| MF | GO:0051540 | metal cluster binding | IEP | Predicted GO |
| BP | GO:0055114 | oxidation-reduction process | IEP | Predicted GO |
| MF | GO:0070279 | vitamin B6 binding | IEP | Predicted GO |
| MF | GO:1990837 | sequence-specific double-stranded DNA binding | IEP | Predicted GO |
| MF | GO:2001070 | starch binding | IEP | Predicted GO |
| InterPro domains | Description | Start | Stop |
| IPR011527 | ABC1_TM_dom | 96 | 374 |
| IPR003439 | ABC_transporter-like | 443 | 592 |
