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- Kfl00696_0070
Kfl00696_0070 (kfl00696_0070_v1.1)
Aliases : kfl00696_0070_v1.1
Description : (at4g31210 : 539.0) DNA topoisomerase, type IA, core; FUNCTIONS IN: DNA topoisomerase activity, DNA topoisomerase type I activity, DNA binding, nucleic acid binding; INVOLVED IN: DNA topological change, DNA unwinding involved in replication, DNA metabolic process; LOCATED IN: chromosome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: DNA topoisomerase, type IA, zn finger (InterPro:IPR013498), DNA topoisomerase, type IA, core (InterPro:IPR000380), DNA topoisomerase, type IA, DNA-binding (InterPro:IPR003602), DNA topoisomerase, type IA, domain 2 (InterPro:IPR003601), DNA topoisomerase, type IA, central (InterPro:IPR013497), DNA topoisomerase, type IA, central region, subdomain 3 (InterPro:IPR013826), DNA topoisomerase I, bacterial-type (InterPro:IPR005733), Toprim domain, subgroup (InterPro:IPR006154), DNA topoisomerase, type IA, central region, subdomain 1 (InterPro:IPR013824), Toprim domain (InterPro:IPR006171); BEST Arabidopsis thaliana protein match is: topoisomerase 3alpha (TAIR:AT5G63920.1); Has 21441 Blast hits to 18441 proteins in 2923 species: Archae - 440; Bacteria - 10015; Metazoa - 1777; Fungi - 750; Plants - 256; Viruses - 35; Other Eukaryotes - 8168 (source: NCBI BLink). & (reliability: 1078.0) & (original description: no original description)
Expression Profile
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
| Type | Description | Actions |
| Neighborhood | Klebsormidium release: Kfl00696_0070 | |
| Cluster | HCCA clusters: Cluster_130 | |
Expression Context Conservation (ECC)
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
| Cre10.g442850 | No alias | DNA topoisomerase, type IA, core | 0.03 | Orthogroups_2024-Update | |
Functional Annotation
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0003674 | molecular_function | None | Extended |
| MF | GO:0003676 | nucleic acid binding | None | Extended |
| MF | GO:0003677 | DNA binding | IEA | InterProScan predictions |
| MF | GO:0003824 | catalytic activity | None | Extended |
| MF | GO:0003916 | DNA topoisomerase activity | IEA | InterProScan predictions |
| MF | GO:0005488 | binding | None | Extended |
| CC | GO:0005575 | cellular_component | None | Extended |
| CC | GO:0005694 | chromosome | IEA | InterProScan predictions |
| BP | GO:0006139 | nucleobase-containing compound metabolic process | None | Extended |
| BP | GO:0006259 | DNA metabolic process | None | Extended |
| BP | GO:0006265 | DNA topological change | IEA | InterProScan predictions |
| BP | GO:0006725 | cellular aromatic compound metabolic process | None | Extended |
| BP | GO:0006807 | nitrogen compound metabolic process | None | Extended |
| BP | GO:0006996 | organelle organization | None | Extended |
| BP | GO:0008150 | biological_process | None | Extended |
| BP | GO:0008152 | metabolic process | None | Extended |
| BP | GO:0009987 | cellular process | None | Extended |
| BP | GO:0016043 | cellular component organization | None | Extended |
| MF | GO:0016853 | isomerase activity | None | Extended |
| BP | GO:0034641 | cellular nitrogen compound metabolic process | None | Extended |
| BP | GO:0043170 | macromolecule metabolic process | None | Extended |
| CC | GO:0043226 | organelle | None | Extended |
| CC | GO:0043228 | non-membrane-bounded organelle | None | Extended |
| CC | GO:0043229 | intracellular organelle | None | Extended |
| CC | GO:0043232 | intracellular non-membrane-bounded organelle | None | Extended |
| BP | GO:0044237 | cellular metabolic process | None | Extended |
| BP | GO:0044238 | primary metabolic process | None | Extended |
| BP | GO:0044260 | cellular macromolecule metabolic process | None | Extended |
| CC | GO:0044424 | intracellular part | None | Extended |
| CC | GO:0044464 | cell part | None | Extended |
| BP | GO:0046483 | heterocycle metabolic process | None | Extended |
| BP | GO:0051276 | chromosome organization | None | Extended |
| BP | GO:0071103 | DNA conformation change | None | Extended |
| BP | GO:0071704 | organic substance metabolic process | None | Extended |
| BP | GO:0071840 | cellular component organization or biogenesis | None | Extended |
| BP | GO:0090304 | nucleic acid metabolic process | None | Extended |
| MF | GO:0097159 | organic cyclic compound binding | None | Extended |
| MF | GO:0140097 | catalytic activity, acting on DNA | None | Extended |
| BP | GO:1901360 | organic cyclic compound metabolic process | None | Extended |
| MF | GO:1901363 | heterocyclic compound binding | None | Extended |
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0004806 | triglyceride lipase activity | IEP | Predicted GO |
| MF | GO:0016298 | lipase activity | IEP | Predicted GO |
| MF | GO:0052689 | carboxylic ester hydrolase activity | IEP | Predicted GO |
