Kfl00713_0040 (kfl00713_0040_v1.1)

Aliases : kfl00713_0040_v1.1

Description : (at3g54640 : 302.0) Catalyzes the conversion of indole-3-glycerolphosphate to indole, the penultimate reaction in the biosynthesis of tryptophan. Functions as a heterocomplex with tryptophan synthase beta subunit (TSA2).; tryptophan synthase alpha chain (TSA1); FUNCTIONS IN: tryptophan synthase activity; INVOLVED IN: tryptophan biosynthetic process, defense response to bacterium, defense response by callose deposition in cell wall; LOCATED IN: chloroplast, chloroplast stroma; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tryptophan synthase, alpha chain, active site (InterPro:IPR018204), Aldolase-type TIM barrel (InterPro:IPR013785), Ribulose-phosphate binding barrel (InterPro:IPR011060), Tryptophan synthase, alpha chain (InterPro:IPR002028); BEST Arabidopsis thaliana protein match is: Aldolase-type TIM barrel family protein (TAIR:AT4G02610.1); Has 7625 Blast hits to 7625 proteins in 2261 species: Archae - 218; Bacteria - 4541; Metazoa - 6; Fungi - 175; Plants - 137; Viruses - 0; Other Eukaryotes - 2548 (source: NCBI BLink). & (p42390|trpa_maize : 246.0) Indole-3-glycerol phosphate lyase, chloroplast precursor (EC 4.1.2.8) (Indole synthase) (Tryptophan synthase alpha chain) (EC 4.2.1.20) (Benzoxazineless 1) - Zea mays (Maize) & (reliability: 604.0) & (original description: no original description)

Gene families : OG_42_0003100 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003100_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00713_0040
Cluster	HCCA clusters: Cluster_109

Target	Alias	Description	ECC score	Gene Family Method
A4A49_16301	No alias	tryptophan synthase alpha chain, chloroplastic	0.02	Orthogroups_2024-Update
A4A49_63173	No alias	tryptophan synthase alpha chain	0.01	Orthogroups_2024-Update
Bradi3g16880	No alias	Aldolase-type TIM barrel family protein	0.03	Orthogroups_2024-Update
Cre12.g528700	No alias	Aldolase-type TIM barrel family protein	0.01	Orthogroups_2024-Update
HORVU3Hr1G003410.1	No alias	subunit alpha of tryptophan synthase complex	0.02	Orthogroups_2024-Update
Sopen01g042100	No alias	Tryptophan synthase alpha chain	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004834	tryptophan synthase activity	IEA	InterProScan predictions
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006568	tryptophan metabolic process	IEA	InterProScan predictions
BP	GO:0006576	cellular biogenic amine metabolic process	None	Extended
BP	GO:0006586	indolalkylamine metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009072	aromatic amino acid family metabolic process	None	Extended
BP	GO:0009308	amine metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016829	lyase activity	None	Extended
MF	GO:0016835	carbon-oxygen lyase activity	None	Extended
MF	GO:0016836	hydro-lyase activity	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0042430	indole-containing compound metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044106	cellular amine metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901605	alpha-amino acid metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000105	histidine biosynthetic process	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003879	ATP phosphoribosyltransferase activity	IEP	Predicted GO
MF	GO:0004017	adenylate kinase activity	IEP	Predicted GO
MF	GO:0004425	indole-3-glycerol-phosphate synthase activity	IEP	Predicted GO
MF	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	IEP	Predicted GO
MF	GO:0004674	protein serine/threonine kinase activity	IEP	Predicted GO
BP	GO:0006547	histidine metabolic process	IEP	Predicted GO
BP	GO:0006605	protein targeting	IEP	Predicted GO
BP	GO:0006612	protein targeting to membrane	IEP	Predicted GO
BP	GO:0006613	cotranslational protein targeting to membrane	IEP	Predicted GO
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	IEP	Predicted GO
BP	GO:0008202	steroid metabolic process	IEP	Predicted GO
MF	GO:0008312	7S RNA binding	IEP	Predicted GO
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEP	Predicted GO
BP	GO:0009073	aromatic amino acid family biosynthetic process	IEP	Predicted GO
CC	GO:0009538	photosystem I reaction center	IEP	Predicted GO
MF	GO:0009982	pseudouridine synthase activity	IEP	Predicted GO
BP	GO:0016125	sterol metabolic process	IEP	Predicted GO
MF	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	IEP	Predicted GO
MF	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016776	phosphotransferase activity, phosphate group as acceptor	IEP	Predicted GO
MF	GO:0016853	isomerase activity	IEP	Predicted GO
MF	GO:0016860	intramolecular oxidoreductase activity	IEP	Predicted GO
MF	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	IEP	Predicted GO
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	IEP	Predicted GO
MF	GO:0019205	nucleobase-containing compound kinase activity	IEP	Predicted GO
BP	GO:0045047	protein targeting to ER	IEP	Predicted GO
MF	GO:0047750	cholestenol delta-isomerase activity	IEP	Predicted GO
CC	GO:0048500	signal recognition particle	IEP	Predicted GO
MF	GO:0050145	nucleoside monophosphate kinase activity	IEP	Predicted GO
BP	GO:0052803	imidazole-containing compound metabolic process	IEP	Predicted GO
BP	GO:0070972	protein localization to endoplasmic reticulum	IEP	Predicted GO
BP	GO:0072599	establishment of protein localization to endoplasmic reticulum	IEP	Predicted GO
BP	GO:0072657	protein localization to membrane	IEP	Predicted GO
BP	GO:0090150	establishment of protein localization to membrane	IEP	Predicted GO
BP	GO:1901615	organic hydroxy compound metabolic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002028	Trp_synthase_suA	112	367

External Links

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Kfl00713_0040 (kfl00713_0040_v1.1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation