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  5. Kfl00852_0040

Kfl00852_0040 (kfl00852_0040_v1.1)


Aliases : kfl00852_0040_v1.1

Description : (at4g32700 : 217.0) Encodes a homolog of Drosophila MUS308 and mammalian DNA polymerase, which prevent spontaneous or DNA damage-induced production of DNA double strand breaks. Two conserved functional domains: an N-terminal superfamily II DNA/RNA helicase domain and a C-terminal prokaryotic-type DNA polymerase I domain. Required for regulated cell division and differentiation in meristems. Mutant plants show morphological defects, such as short roots, serrated leaves, and fasciation, as well as defective patterns of cell division and differentiation in the meristem. Mutant plants had 2.5 to 4.5-fold higher expression of ATGR1, ATBRCA1 and RAD51 genes. TEB is required for normal progression of DNA replication and for correct expression of genes during development.; helicases;ATP-dependent helicases;nucleic acid binding;ATP binding;DNA-directed DNA polymerases;DNA binding; FUNCTIONS IN: in 6 functions; INVOLVED IN: regulation of gene expression, DNA replication, DNA recombination, photomorphogenesis; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA-directed DNA polymerase, family A, palm domain (InterPro:IPR001098), DNA/RNA helicase, C-terminal (InterPro:IPR001650), DNA polymerase A domain (InterPro:IPR002298), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: U5 small nuclear ribonucleoprotein helicase (TAIR:AT2G42270.1); Has 17628 Blast hits to 16579 proteins in 2941 species: Archae - 600; Bacteria - 7507; Metazoa - 1254; Fungi - 1190; Plants - 590; Viruses - 412; Other Eukaryotes - 6075 (source: NCBI BLink). & (reliability: 434.0) & (original description: no original description)


Gene families : OG_42_0004411 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004411_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00852_0040
Cluster HCCA clusters: Cluster_205


Type GO Term Name Evidence Source
MF GO:0003677 DNA binding IEA InterProScan predictions
MF GO:0003887 DNA-directed DNA polymerase activity IEA InterProScan predictions
BP GO:0006260 DNA replication IEA InterProScan predictions
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Type GO Term Name Evidence Source
CC GO:0000786 nucleosome IEP Predicted GO
MF GO:0015079 potassium ion transmembrane transporter activity IEP Predicted GO
CC GO:0032993 protein-DNA complex IEP Predicted GO
CC GO:0044815 DNA packaging complex IEP Predicted GO
BP GO:0071805 potassium ion transmembrane transport IEP Predicted GO
InterPro domains Description Start Stop
IPR001098 DNA-dir_DNA_pol_A_palm_dom 462 814
No external refs found!