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- Kfl00881_0020
Kfl00881_0020 (kfl00881_0020_v1.1)
Aliases : kfl00881_0020_v1.1
Description : (at1g15750 : 1113.0) Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top help of the embryo during the transition stage of embryogenesis. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background.; TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 2226.0) & (original description: no original description)
Expression Profile
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
| Type | Description | Actions |
| Neighborhood | Klebsormidium release: Kfl00881_0020 | |
| Cluster | HCCA clusters: Cluster_37 | |
Expression Context Conservation (ECC)
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
| Glyma.13G158800 | No alias | WUS-interacting protein 2 | 0.02 | Orthogroups_2024-Update | |
| Glyma.15G006100 | No alias | TOPLESS-related 1 | 0.06 | Orthogroups_2024-Update | |
| Glyma.17G112500 | No alias | WUS-interacting protein 2 | 0.02 | Orthogroups_2024-Update | |
| HORVU6Hr1G036010.9 | No alias | Unknown function | 0.04 | Orthogroups_2024-Update | |
| MA_10430083g0010 | No alias | (at1g15750 : 1644.0) Encodes a protein with several WD40... | 0.02 | Orthogroups_2024-Update | |
| MA_10436445g0020 | No alias | (at1g15750 : 1515.0) Encodes a protein with several WD40... | 0.02 | Orthogroups_2024-Update | |
| PSME_00014296-RA | No alias | (at1g15750 : 556.0) Encodes a protein with several WD40... | 0.02 | Orthogroups_2024-Update | |
| PSME_00033018-RA | No alias | (at1g15750 : 417.0) Encodes a protein with several WD40... | 0.01 | Orthogroups_2024-Update | |
Functional Annotation
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0003674 | molecular_function | None | Extended |
| MF | GO:0005488 | binding | None | Extended |
| MF | GO:0005515 | protein binding | IEA | InterProScan predictions |
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0005507 | copper ion binding | IEP | Predicted GO |
| MF | GO:0008131 | primary amine oxidase activity | IEP | Predicted GO |
| MF | GO:0008144 | drug binding | IEP | Predicted GO |
| MF | GO:0009055 | electron transfer activity | IEP | Predicted GO |
| BP | GO:0009308 | amine metabolic process | IEP | Predicted GO |
| MF | GO:0016491 | oxidoreductase activity | IEP | Predicted GO |
| MF | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | IEP | Predicted GO |
| MF | GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors | IEP | Predicted GO |
| MF | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | IEP | Predicted GO |
| MF | GO:0016903 | oxidoreductase activity, acting on the aldehyde or oxo group of donors | IEP | Predicted GO |
| MF | GO:0043167 | ion binding | IEP | Predicted GO |
| MF | GO:0043169 | cation binding | IEP | Predicted GO |
| MF | GO:0046872 | metal ion binding | IEP | Predicted GO |
| MF | GO:0046914 | transition metal ion binding | IEP | Predicted GO |
| MF | GO:0048037 | cofactor binding | IEP | Predicted GO |
| MF | GO:0048038 | quinone binding | IEP | Predicted GO |
| MF | GO:0051536 | iron-sulfur cluster binding | IEP | Predicted GO |
| MF | GO:0051540 | metal cluster binding | IEP | Predicted GO |
| InterPro domains | Description | Start | Stop |
| IPR001680 | WD40_repeat | 423 | 456 |
| IPR001680 | WD40_repeat | 895 | 928 |