Kfl00909_0020 (kfl00909_0020_v1.1)


Aliases : kfl00909_0020_v1.1

Description : (at3g21640 : 350.0) encodes a 42 kDa FK506-binding protein (AtFKBP42) that possesses similarity to multidomain peptidyl-prolyl cis/trans isomerases (PPIases, EC 5.2.1.8), which are known to be components of mammalian steroid hormone receptor complexes. The protein appears to be localized to the plasma membrane by electron microscopy and binds to HSP90.1 and calmodulin in vitro. It also aggregates citrate synthase in vitro but does NOT show PPIase activity in vivo. Mutants are reduced in size and exhibit disoriented growth in all organs.; TWISTED DWARF 1 (TWD1); CONTAINS InterPro DOMAIN/s: Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide TPR2 (InterPro:IPR013105), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734), Peptidyl-prolyl cis-trans isomerase, FKBP-type (InterPro:IPR001179); BEST Arabidopsis thaliana protein match is: rotamase FKBP 1 (TAIR:AT3G25230.2); Has 6043 Blast hits to 5631 proteins in 871 species: Archae - 12; Bacteria - 1331; Metazoa - 2461; Fungi - 414; Plants - 774; Viruses - 0; Other Eukaryotes - 1051 (source: NCBI BLink). & (q43207|fkb70_wheat : 132.0) 70 kDa peptidyl-prolyl isomerase (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) - Triticum aestivum (Wheat) & (reliability: 700.0) & (original description: no original description)


Gene families : OG_42_0005483 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005483_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00909_0020
Cluster HCCA clusters: Cluster_106

Target Alias Description ECC score Gene Family Method Actions
Bradi4g42842 No alias FKBP-type peptidyl-prolyl cis-trans isomerase family protein 0.02 Orthogroups_2024-Update
Glyma.12G008300 No alias FKBP-type peptidyl-prolyl cis-trans isomerase family protein 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003682 chromatin binding IEP Predicted GO
MF GO:0003909 DNA ligase activity IEP Predicted GO
MF GO:0003910 DNA ligase (ATP) activity IEP Predicted GO
MF GO:0004518 nuclease activity IEP Predicted GO
CC GO:0005643 nuclear pore IEP Predicted GO
BP GO:0006281 DNA repair IEP Predicted GO
BP GO:0006284 base-excision repair IEP Predicted GO
BP GO:0006479 protein methylation IEP Predicted GO
BP GO:0006612 protein targeting to membrane IEP Predicted GO
BP GO:0006613 cotranslational protein targeting to membrane IEP Predicted GO
BP GO:0006614 SRP-dependent cotranslational protein targeting to membrane IEP Predicted GO
BP GO:0006950 response to stress IEP Predicted GO
BP GO:0006974 cellular response to DNA damage stimulus IEP Predicted GO
BP GO:0007010 cytoskeleton organization IEP Predicted GO
MF GO:0008170 N-methyltransferase activity IEP Predicted GO
BP GO:0008213 protein alkylation IEP Predicted GO
MF GO:0008276 protein methyltransferase activity IEP Predicted GO
MF GO:0008312 7S RNA binding IEP Predicted GO
MF GO:0016278 lysine N-methyltransferase activity IEP Predicted GO
MF GO:0016279 protein-lysine N-methyltransferase activity IEP Predicted GO
BP GO:0016571 histone methylation IEP Predicted GO
MF GO:0016886 ligase activity, forming phosphoric ester bonds IEP Predicted GO
BP GO:0018022 peptidyl-lysine methylation IEP Predicted GO
MF GO:0018024 histone-lysine N-methyltransferase activity IEP Predicted GO
BP GO:0018193 peptidyl-amino acid modification IEP Predicted GO
BP GO:0033554 cellular response to stress IEP Predicted GO
BP GO:0034968 histone lysine methylation IEP Predicted GO
MF GO:0042054 histone methyltransferase activity IEP Predicted GO
BP GO:0046907 intracellular transport IEP Predicted GO
CC GO:0048500 signal recognition particle IEP Predicted GO
BP GO:0050896 response to stimulus IEP Predicted GO
BP GO:0051649 establishment of localization in cell IEP Predicted GO
BP GO:0051716 cellular response to stimulus IEP Predicted GO
BP GO:0072657 protein localization to membrane IEP Predicted GO
BP GO:0090150 establishment of protein localization to membrane IEP Predicted GO
InterPro domains Description Start Stop
IPR001179 PPIase_FKBP_dom 77 169
IPR013105 TPR_2 279 311
No external refs found!