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  5. Kfl00946_0010

Kfl00946_0010 (kfl00946_0010_v1.1)


Aliases : kfl00946_0010_v1.1

Description : (at5g19400 : 283.0) Encodes SMG7, a protein that possesses an evolutionarily conserved EST1 domain and exhibits strong homology to human SMG6 (EST1A) and SMG7 (EST1C) proteins. SMG7 plays an evolutionarily conserved role in nonsense-mediated RNA decay (NMD). Required for exit from meiosis. Hypomorphic smg7 alleles render mutant plants sterile by causing an unusual cell-cycle arrest in anaphase II that is characterized by delayed chromosome decondensation and aberrant rearrangement of the meiotic spindle. Disruption of SMG7 causes embryonic lethality.; SMG7; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: meiosis, spindle assembly involved in meiosis, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Telomerase activating protein Est1 (InterPro:IPR019458); BEST Arabidopsis thaliana protein match is: Telomerase activating protein Est1 (TAIR:AT1G28260.2). & (reliability: 566.0) & (original description: no original description)


Gene families : OG_42_0003131 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003131_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood Klebsormidium release: Kfl00946_0010
Cluster HCCA clusters: Cluster_40

Target Alias Description ECC score Gene Family Method Actions
A4A49_14506 No alias protein smg7 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source
MF GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity IEP Predicted GO
MF GO:0004180 carboxypeptidase activity IEP Predicted GO
MF GO:0004185 serine-type carboxypeptidase activity IEP Predicted GO
MF GO:0004594 pantothenate kinase activity IEP Predicted GO
MF GO:0004649 poly(ADP-ribose) glycohydrolase activity IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
MF GO:0005534 galactose binding IEP Predicted GO
BP GO:0006270 DNA replication initiation IEP Predicted GO
BP GO:0006810 transport IEP Predicted GO
BP GO:0009451 RNA modification IEP Predicted GO
BP GO:0015936 coenzyme A metabolic process IEP Predicted GO
BP GO:0015937 coenzyme A biosynthetic process IEP Predicted GO
MF GO:0016289 CoA hydrolase activity IEP Predicted GO
MF GO:0016790 thiolester hydrolase activity IEP Predicted GO
CC GO:0030119 AP-type membrane coat adaptor complex IEP Predicted GO
BP GO:0033865 nucleoside bisphosphate metabolic process IEP Predicted GO
BP GO:0033866 nucleoside bisphosphate biosynthetic process IEP Predicted GO
BP GO:0033875 ribonucleoside bisphosphate metabolic process IEP Predicted GO
BP GO:0034030 ribonucleoside bisphosphate biosynthetic process IEP Predicted GO
BP GO:0034032 purine nucleoside bisphosphate metabolic process IEP Predicted GO
BP GO:0034033 purine nucleoside bisphosphate biosynthetic process IEP Predicted GO
MF GO:0043015 gamma-tubulin binding IEP Predicted GO
CC GO:0044599 AP-5 adaptor complex IEP Predicted GO
MF GO:0048029 monosaccharide binding IEP Predicted GO
BP GO:0051179 localization IEP Predicted GO
BP GO:0051234 establishment of localization IEP Predicted GO
BP GO:0055085 transmembrane transport IEP Predicted GO
MF GO:0070008 serine-type exopeptidase activity IEP Predicted GO
CC GO:0071203 WASH complex IEP Predicted GO
InterPro domains Description Start Stop
IPR019458 EST1 67 204
IPR018834 DNA/RNA-bd_Est1-type 216 519
No external refs found!