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- Kfl00987_0050
Kfl00987_0050 (kfl00987_0050_v1.1)
Aliases : kfl00987_0050_v1.1
Description : (at5g22770 : 768.0) alpha-adaptin (alpha-ADR); FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: intracellular protein transport, vesicle-mediated transport, protein transport; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: male gametophyte, pollen tube, leaf; EXPRESSED DURING: M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain (InterPro:IPR008152), Adaptor protein complex AP-2, alpha subunit (InterPro:IPR017104), Armadillo-like helical (InterPro:IPR011989), Clathrin adaptor, alpha-adaptin, appendage, Ig-like subdomain (InterPro:IPR013038), Clathrin/coatomer adaptor, adaptin-like, N-terminal (InterPro:IPR002553), Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain (InterPro:IPR003164), Armadillo-type fold (InterPro:IPR016024), Clathrin alpha-adaptin/coatomer adaptor, appendage, C-terminal subdomain (InterPro:IPR015873), Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain (InterPro:IPR009028), Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain (InterPro:IPR013041); BEST Arabidopsis thaliana protein match is: Adaptor protein complex AP-2, alpha subunit (TAIR:AT5G22780.1); Has 2529 Blast hits to 2470 proteins in 297 species: Archae - 0; Bacteria - 0; Metazoa - 987; Fungi - 687; Plants - 265; Viruses - 0; Other Eukaryotes - 590 (source: NCBI BLink). & (reliability: 1536.0) & (original description: no original description)
Expression Profile
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
| Type | Description | Actions |
| Neighborhood | Klebsormidium release: Kfl00987_0050 | |
| Cluster | HCCA clusters: Cluster_82 | |
Expression Context Conservation (ECC)
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
| 230624 | No alias | Adaptor protein complex AP-2, alpha subunit | 0.02 | Orthogroups_2024-Update | |
| Bradi1g77770 | No alias | Adaptor protein complex AP-2, alpha subunit | 0.05 | Orthogroups_2024-Update | |
| Glyma.12G180600 | No alias | Adaptor protein complex AP-2, alpha subunit | 0.04 | Orthogroups_2024-Update | |
| Glyma.13G320200 | No alias | Adaptor protein complex AP-2, alpha subunit | 0.03 | Orthogroups_2024-Update | |
| HORVU4Hr1G089310.19 | No alias | large subunit alpha of AP-2 cargo adaptor complex | 0.05 | Orthogroups_2024-Update | |
| LOC_Os03g02150 | No alias | adapitin protein, putative, expressed | 0.02 | Orthogroups_2024-Update | |
| Mp2g23200.1 | No alias | large subunit alpha of AP-2 cargo adaptor complex | 0.02 | Orthogroups_2024-Update | |
| PSME_00007847-RA | No alias | (at5g22770 : 1409.0) alpha-adaptin (alpha-ADR);... | 0.01 | Orthogroups_2024-Update | |
| Pp1s507_6V6 | No alias | MDJ22.19; adaptin family [Arabidopsis thaliana] | 0.03 | Orthogroups_2024-Update | |
| Sobic.001G534800.1 | No alias | large subunit alpha of AP-2 cargo adaptor complex | 0.02 | Orthogroups_2024-Update | |
| Solyc11g066760 | No alias | AP-2 complex subunit alpha-1 (AHRD V3.3 *** AP2A1_ARATH) | 0.01 | Orthogroups_2024-Update | |
| Sopen06g031070 | No alias | Adaptin N terminal region | 0.03 | Orthogroups_2024-Update | |
| evm.model.tig00021312.53 | No alias | (at5g22770 : 587.0) alpha-adaptin (alpha-ADR); FUNCTIONS... | 0.03 | Orthogroups_2024-Update | |
Functional Annotation
| Type | GO Term | Name | Evidence | Source |
| CC | GO:0005575 | cellular_component | None | Extended |
| BP | GO:0006810 | transport | None | Extended |
| BP | GO:0006886 | intracellular protein transport | IEA | InterProScan predictions |
| BP | GO:0008104 | protein localization | None | Extended |
| BP | GO:0008150 | biological_process | None | Extended |
| BP | GO:0015031 | protein transport | None | Extended |
| BP | GO:0015833 | peptide transport | None | Extended |
| BP | GO:0016192 | vesicle-mediated transport | IEA | InterProScan predictions |
| CC | GO:0030117 | membrane coat | IEA | InterProScan predictions |
| CC | GO:0030119 | AP-type membrane coat adaptor complex | None | Extended |
| CC | GO:0030131 | clathrin adaptor complex | IEA | InterProScan predictions |
| CC | GO:0032991 | protein-containing complex | None | Extended |
| BP | GO:0033036 | macromolecule localization | None | Extended |
| BP | GO:0042886 | amide transport | None | Extended |
| CC | GO:0044424 | intracellular part | None | Extended |
| CC | GO:0044425 | membrane part | None | Extended |
| CC | GO:0044444 | cytoplasmic part | None | Extended |
| CC | GO:0044464 | cell part | None | Extended |
| BP | GO:0045184 | establishment of protein localization | None | Extended |
| BP | GO:0046907 | intracellular transport | None | Extended |
| BP | GO:0051179 | localization | None | Extended |
| BP | GO:0051234 | establishment of localization | None | Extended |
| BP | GO:0051641 | cellular localization | None | Extended |
| BP | GO:0051649 | establishment of localization in cell | None | Extended |
| BP | GO:0071702 | organic substance transport | None | Extended |
| BP | GO:0071705 | nitrogen compound transport | None | Extended |
| CC | GO:0098796 | membrane protein complex | None | Extended |
| Type | GO Term | Name | Evidence | Source |
| CC | GO:0000145 | exocyst | IEP | Predicted GO |
| MF | GO:0000166 | nucleotide binding | IEP | Predicted GO |
| BP | GO:0000375 | RNA splicing, via transesterification reactions | IEP | Predicted GO |
| BP | GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | IEP | Predicted GO |
| BP | GO:0000398 | mRNA splicing, via spliceosome | IEP | Predicted GO |
| MF | GO:0003872 | 6-phosphofructokinase activity | IEP | Predicted GO |
| MF | GO:0003873 | 6-phosphofructo-2-kinase activity | IEP | Predicted GO |
| MF | GO:0005488 | binding | IEP | Predicted GO |
| MF | GO:0005524 | ATP binding | IEP | Predicted GO |
| CC | GO:0005643 | nuclear pore | IEP | Predicted GO |
| CC | GO:0005737 | cytoplasm | IEP | Predicted GO |
| BP | GO:0005996 | monosaccharide metabolic process | IEP | Predicted GO |
| BP | GO:0006000 | fructose metabolic process | IEP | Predicted GO |
| BP | GO:0006013 | mannose metabolic process | IEP | Predicted GO |
| BP | GO:0006887 | exocytosis | IEP | Predicted GO |
| BP | GO:0006888 | ER to Golgi vesicle-mediated transport | IEP | Predicted GO |
| BP | GO:0006904 | vesicle docking involved in exocytosis | IEP | Predicted GO |
| MF | GO:0008131 | primary amine oxidase activity | IEP | Predicted GO |
| MF | GO:0008144 | drug binding | IEP | Predicted GO |
| MF | GO:0008289 | lipid binding | IEP | Predicted GO |
| MF | GO:0008443 | phosphofructokinase activity | IEP | Predicted GO |
| BP | GO:0009308 | amine metabolic process | IEP | Predicted GO |
| MF | GO:0015077 | monovalent inorganic cation transmembrane transporter activity | IEP | Predicted GO |
| MF | GO:0015079 | potassium ion transmembrane transporter activity | IEP | Predicted GO |
| MF | GO:0015399 | primary active transmembrane transporter activity | IEP | Predicted GO |
| MF | GO:0015405 | P-P-bond-hydrolysis-driven transmembrane transporter activity | IEP | Predicted GO |
| MF | GO:0016301 | kinase activity | IEP | Predicted GO |
| MF | GO:0016307 | phosphatidylinositol phosphate kinase activity | IEP | Predicted GO |
| MF | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | IEP | Predicted GO |
| MF | GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors | IEP | Predicted GO |
| MF | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | IEP | Predicted GO |
| MF | GO:0016772 | transferase activity, transferring phosphorus-containing groups | IEP | Predicted GO |
| MF | GO:0016773 | phosphotransferase activity, alcohol group as acceptor | IEP | Predicted GO |
| MF | GO:0016887 | ATPase activity | IEP | Predicted GO |
| MF | GO:0017056 | structural constituent of nuclear pore | IEP | Predicted GO |
| MF | GO:0017069 | snRNA binding | IEP | Predicted GO |
| MF | GO:0017070 | U6 snRNA binding | IEP | Predicted GO |
| MF | GO:0017076 | purine nucleotide binding | IEP | Predicted GO |
| MF | GO:0019200 | carbohydrate kinase activity | IEP | Predicted GO |
| BP | GO:0019318 | hexose metabolic process | IEP | Predicted GO |
| BP | GO:0022406 | membrane docking | IEP | Predicted GO |
| MF | GO:0022804 | active transmembrane transporter activity | IEP | Predicted GO |
| CC | GO:0030120 | vesicle coat | IEP | Predicted GO |
| CC | GO:0030126 | COPI vesicle coat | IEP | Predicted GO |
| CC | GO:0030127 | COPII vesicle coat | IEP | Predicted GO |
| MF | GO:0030554 | adenyl nucleotide binding | IEP | Predicted GO |
| MF | GO:0030623 | U5 snRNA binding | IEP | Predicted GO |
| MF | GO:0032553 | ribonucleotide binding | IEP | Predicted GO |
| MF | GO:0032555 | purine ribonucleotide binding | IEP | Predicted GO |
| MF | GO:0032559 | adenyl ribonucleotide binding | IEP | Predicted GO |
| BP | GO:0032940 | secretion by cell | IEP | Predicted GO |
| MF | GO:0035639 | purine ribonucleoside triphosphate binding | IEP | Predicted GO |
| MF | GO:0036094 | small molecule binding | IEP | Predicted GO |
| MF | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | IEP | Predicted GO |
| MF | GO:0043167 | ion binding | IEP | Predicted GO |
| MF | GO:0043168 | anion binding | IEP | Predicted GO |
| MF | GO:0043492 | ATPase activity, coupled to movement of substances | IEP | Predicted GO |
| CC | GO:0044433 | cytoplasmic vesicle part | IEP | Predicted GO |
| CC | GO:0044448 | cell cortex part | IEP | Predicted GO |
| BP | GO:0046903 | secretion | IEP | Predicted GO |
| MF | GO:0048038 | quinone binding | IEP | Predicted GO |
| BP | GO:0048193 | Golgi vesicle transport | IEP | Predicted GO |
| BP | GO:0048278 | vesicle docking | IEP | Predicted GO |
| BP | GO:0051640 | organelle localization | IEP | Predicted GO |
| BP | GO:0071805 | potassium ion transmembrane transport | IEP | Predicted GO |
| MF | GO:0097367 | carbohydrate derivative binding | IEP | Predicted GO |
| BP | GO:0140029 | exocytic process | IEP | Predicted GO |
| BP | GO:0140056 | organelle localization by membrane tethering | IEP | Predicted GO |
| MF | GO:1901265 | nucleoside phosphate binding | IEP | Predicted GO |
| InterPro domains | Description | Start | Stop |
| IPR008152 | Clathrin_a/b/g-adaptin_app_Ig | 739 | 834 |
| IPR003164 | Clathrin_a-adaptin_app_sub_C | 847 | 956 |
| IPR002553 | Clathrin/coatomer_adapt-like_N | 25 | 579 |
