Description : (p29102|leu3_brana : 175.0) 3-isopropylmalate dehydrogenase, chloroplast precursor (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) - Brassica napus (Rape) & (at1g80560 : 173.0) The AtIMD2 is one out of 3 genes encoding the enzyme 3-isopropylmalate dehydrogenase involved in leucine biosynthesis in Arabidopsis. Its subcellular location has been targeted to plastids.; isopropylmalate dehydrogenase 2 (IMD2); FUNCTIONS IN: 3-isopropylmalate dehydrogenase activity; INVOLVED IN: leucine biosynthetic process, metabolic process; LOCATED IN: chloroplast, chloroplast stroma, plastid, chloroplast envelope; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Isopropylmalate dehydrogenase (InterPro:IPR004429), Isocitrate/isopropylmalate dehydrogenase (InterPro:IPR001804), Isocitrate/isopropylmalate dehydrogenase, conserved site (InterPro:IPR019818); BEST Arabidopsis thaliana protein match is: isopropylmalate dehydrogenase 3 (TAIR:AT1G31180.1); Has 15265 Blast hits to 15265 proteins in 2613 species: Archae - 395; Bacteria - 8292; Metazoa - 578; Fungi - 832; Plants - 243; Viruses - 0; Other Eukaryotes - 4925 (source: NCBI BLink). & (reliability: 346.0) & (original description: no original description)
Gene families : OG_42_0003624 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003624_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_10426367g0010 | |
Cluster | HCCA clusters: Cluster_6 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Pp1s12_40V6 | No alias | 3-isopropylmalate dehydrogenase | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | IEA | InterProScan predictions |
BP | GO:0055114 | oxidation-reduction process | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003697 | single-stranded DNA binding | IEP | Predicted GO |
MF | GO:0004367 | glycerol-3-phosphate dehydrogenase [NAD+] activity | IEP | Predicted GO |
MF | GO:0004843 | thiol-dependent ubiquitin-specific protease activity | IEP | Predicted GO |
BP | GO:0006072 | glycerol-3-phosphate metabolic process | IEP | Predicted GO |
BP | GO:0009056 | catabolic process | IEP | Predicted GO |
MF | GO:0016597 | amino acid binding | IEP | Predicted GO |
MF | GO:0016743 | carboxyl- or carbamoyltransferase activity | IEP | Predicted GO |
MF | GO:0019783 | ubiquitin-like protein-specific protease activity | IEP | Predicted GO |
MF | GO:0031406 | carboxylic acid binding | IEP | Predicted GO |
MF | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity | IEP | Predicted GO |
MF | GO:0043177 | organic acid binding | IEP | Predicted GO |
BP | GO:0046168 | glycerol-3-phosphate catabolic process | IEP | Predicted GO |
BP | GO:0046434 | organophosphate catabolic process | IEP | Predicted GO |
MF | GO:0051287 | NAD binding | IEP | Predicted GO |
BP | GO:0052646 | alditol phosphate metabolic process | IEP | Predicted GO |
MF | GO:0101005 | ubiquitinyl hydrolase activity | IEP | Predicted GO |
BP | GO:1901136 | carbohydrate derivative catabolic process | IEP | Predicted GO |
BP | GO:1901575 | organic substance catabolic process | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR024084 | IsoPropMal-DH-like_dom | 53 | 162 |
No external refs found! |