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Description : (q06509|comt1_maize : 274.0) Caffeic acid 3-O-methyltransferase (EC 2.1.1.68) (S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase) (COMT) (CAOMT) - Zea mays (Maize) & (at5g54160 : 261.0) A caffeic acid/5-hydroxyferulic acid O-methyltransferase. Interacts with 14-4-3 proteins in yeast 2 hybrid assay. AtOMT1 (At5g54160) encodes a flavonol 3Ã-O-methyltransferase that is highly active towards quercetin and myricetin. The substrate specificity identifies the enzyme as flavonol 3Ã-methyltransferase which replaces the former annotation of the gene to encode a caffeic acid/5-hydroxyferulic acid O-methyltransferase; O-methyltransferase 1 (OMT1); FUNCTIONS IN: myricetin 3'-O-methyltransferase activity, quercetin 3-O-methyltransferase activity, caffeate O-methyltransferase activity; INVOLVED IN: lignin biosynthetic process, flavonol biosynthetic process; LOCATED IN: cytosol, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase family protein (TAIR:AT1G77520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 522.0) & (original description: no original description)
Gene families : OG_42_0000016 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000016_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | Picea release: MA_10426788g0010 | |
| Cluster | HCCA clusters: Cluster_153 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| 76630 | No alias | O-methyltransferase 1 | 0.02 | Orthogroups_2024-Update | |
| 95652 | No alias | O-methyltransferase 1 | 0.03 | Orthogroups_2024-Update | |
| A4A49_03214 | No alias | caffeic acid 3-o-methyltransferase | 0.03 | Orthogroups_2024-Update | |
| LOC_Os06g16960 | No alias | O-methyltransferase, putative, expressed | 0.02 | Orthogroups_2024-Update | |
| LOC_Os11g20080 | No alias | O-methyltransferase, putative, expressed | 0.02 | Orthogroups_2024-Update | |
| MA_74925g0020 | No alias | no hits & (original description: no original description) | 0.03 | Orthogroups_2024-Update | |
| PSME_00041841-RA | No alias | (q8w013|comt1_catro : 270.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
| Potri.011G059600 | No alias | O-methyltransferase family protein | 0.02 | Orthogroups_2024-Update | |
| Potri.013G143800 | No alias | O-methyltransferase family protein | 0.02 | Orthogroups_2024-Update | |
| Seita.3G245700.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
| Sobic.007G058800.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0008171 | O-methyltransferase activity | IEA | InterProScan predictions |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0004672 | protein kinase activity | IEP | Predicted GO |
| MF | GO:0005524 | ATP binding | IEP | Predicted GO |
| CC | GO:0005667 | transcription factor complex | IEP | Predicted GO |
| CC | GO:0005669 | transcription factor TFIID complex | IEP | Predicted GO |
| CC | GO:0005739 | mitochondrion | IEP | Predicted GO |
| BP | GO:0006464 | cellular protein modification process | IEP | Predicted GO |
| BP | GO:0006468 | protein phosphorylation | IEP | Predicted GO |
| BP | GO:0006793 | phosphorus metabolic process | IEP | Predicted GO |
| BP | GO:0006796 | phosphate-containing compound metabolic process | IEP | Predicted GO |
| BP | GO:0006807 | nitrogen compound metabolic process | IEP | Predicted GO |
| BP | GO:0008037 | cell recognition | IEP | Predicted GO |
| MF | GO:0008144 | drug binding | IEP | Predicted GO |
| MF | GO:0016301 | kinase activity | IEP | Predicted GO |
| BP | GO:0016310 | phosphorylation | IEP | Predicted GO |
| MF | GO:0016772 | transferase activity, transferring phosphorus-containing groups | IEP | Predicted GO |
| MF | GO:0016773 | phosphotransferase activity, alcohol group as acceptor | IEP | Predicted GO |
| BP | GO:0019538 | protein metabolic process | IEP | Predicted GO |
| BP | GO:0022414 | reproductive process | IEP | Predicted GO |
| BP | GO:0036211 | protein modification process | IEP | Predicted GO |
| BP | GO:0043170 | macromolecule metabolic process | IEP | Predicted GO |
| BP | GO:0043412 | macromolecule modification | IEP | Predicted GO |
| BP | GO:0044260 | cellular macromolecule metabolic process | IEP | Predicted GO |
| BP | GO:0044267 | cellular protein metabolic process | IEP | Predicted GO |
| CC | GO:0044798 | nuclear transcription factor complex | IEP | Predicted GO |
| MF | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer | IEP | Predicted GO |
| BP | GO:0048544 | recognition of pollen | IEP | Predicted GO |
| CC | GO:0090575 | RNA polymerase II transcription factor complex | IEP | Predicted GO |
| MF | GO:0140096 | catalytic activity, acting on a protein | IEP | Predicted GO |
| BP | GO:1901564 | organonitrogen compound metabolic process | IEP | Predicted GO |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR001077 | O_MeTrfase_2 | 11 | 212 |
| No external refs found! |