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- MA_10428900g0010
MA_10428900g0010
Description : (at2g32000 : 604.0) DNA topoisomerase, type IA, core; FUNCTIONS IN: DNA topoisomerase activity, DNA topoisomerase type I activity, DNA binding, nucleic acid binding; INVOLVED IN: DNA topological change, DNA unwinding involved in replication, DNA metabolic process; LOCATED IN: endomembrane system, chromosome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Toprim domain, subgroup (InterPro:IPR006154), DNA topoisomerase, type IA, central region, subdomain 1 (InterPro:IPR013824), DNA topoisomerase, type IA, core (InterPro:IPR000380), Toprim domain (InterPro:IPR006171), DNA topoisomerase, type IA, DNA-binding (InterPro:IPR003602), DNA topoisomerase, type IA, domain 2 (InterPro:IPR003601), DNA topoisomerase, type IA, central (InterPro:IPR013497), DNA topoisomerase, type IA, central region, subdomain 3 (InterPro:IPR013826); BEST Arabidopsis thaliana protein match is: topoisomerase 3alpha (TAIR:AT5G63920.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 1208.0) & (original description: no original description)
Expression Profile
Attention: This gene has low abundance.
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
| Type | Description | Actions |
| Neighborhood | Picea release: MA_10428900g0010 | |
Expression Context Conservation (ECC)
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
| Solyc05g014730 | No alias | No description available | 0.03 | Orthogroups_2024-Update | |
Functional Annotation
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0003674 | molecular_function | None | Extended |
| MF | GO:0003676 | nucleic acid binding | None | Extended |
| MF | GO:0003677 | DNA binding | IEA | InterProScan predictions |
| MF | GO:0003824 | catalytic activity | None | Extended |
| MF | GO:0003916 | DNA topoisomerase activity | IEA | InterProScan predictions |
| MF | GO:0005488 | binding | None | Extended |
| BP | GO:0006139 | nucleobase-containing compound metabolic process | None | Extended |
| BP | GO:0006259 | DNA metabolic process | None | Extended |
| BP | GO:0006265 | DNA topological change | IEA | InterProScan predictions |
| BP | GO:0006725 | cellular aromatic compound metabolic process | None | Extended |
| BP | GO:0006807 | nitrogen compound metabolic process | None | Extended |
| BP | GO:0006996 | organelle organization | None | Extended |
| BP | GO:0008150 | biological_process | None | Extended |
| BP | GO:0008152 | metabolic process | None | Extended |
| BP | GO:0009987 | cellular process | None | Extended |
| BP | GO:0016043 | cellular component organization | None | Extended |
| MF | GO:0016853 | isomerase activity | None | Extended |
| BP | GO:0034641 | cellular nitrogen compound metabolic process | None | Extended |
| BP | GO:0043170 | macromolecule metabolic process | None | Extended |
| BP | GO:0044237 | cellular metabolic process | None | Extended |
| BP | GO:0044238 | primary metabolic process | None | Extended |
| BP | GO:0044260 | cellular macromolecule metabolic process | None | Extended |
| BP | GO:0046483 | heterocycle metabolic process | None | Extended |
| BP | GO:0051276 | chromosome organization | None | Extended |
| BP | GO:0071103 | DNA conformation change | None | Extended |
| BP | GO:0071704 | organic substance metabolic process | None | Extended |
| BP | GO:0071840 | cellular component organization or biogenesis | None | Extended |
| BP | GO:0090304 | nucleic acid metabolic process | None | Extended |
| MF | GO:0097159 | organic cyclic compound binding | None | Extended |
| MF | GO:0140097 | catalytic activity, acting on DNA | None | Extended |
| BP | GO:1901360 | organic cyclic compound metabolic process | None | Extended |
| MF | GO:1901363 | heterocyclic compound binding | None | Extended |
| Type | GO Term | Name | Evidence | Source |
| MF | GO:0003690 | double-stranded DNA binding | IEP | Predicted GO |
| BP | GO:0006355 | regulation of transcription, DNA-templated | IEP | Predicted GO |
| BP | GO:0009889 | regulation of biosynthetic process | IEP | Predicted GO |
| BP | GO:0010468 | regulation of gene expression | IEP | Predicted GO |
| BP | GO:0010556 | regulation of macromolecule biosynthetic process | IEP | Predicted GO |
| BP | GO:0019219 | regulation of nucleobase-containing compound metabolic process | IEP | Predicted GO |
| BP | GO:0019222 | regulation of metabolic process | IEP | Predicted GO |
| BP | GO:0031323 | regulation of cellular metabolic process | IEP | Predicted GO |
| BP | GO:0031326 | regulation of cellular biosynthetic process | IEP | Predicted GO |
| BP | GO:0050794 | regulation of cellular process | IEP | Predicted GO |
| BP | GO:0051171 | regulation of nitrogen compound metabolic process | IEP | Predicted GO |
| BP | GO:0051252 | regulation of RNA metabolic process | IEP | Predicted GO |
| BP | GO:0060255 | regulation of macromolecule metabolic process | IEP | Predicted GO |
| BP | GO:0080090 | regulation of primary metabolic process | IEP | Predicted GO |
| BP | GO:1903506 | regulation of nucleic acid-templated transcription | IEP | Predicted GO |
| BP | GO:2000112 | regulation of cellular macromolecule biosynthetic process | IEP | Predicted GO |
| BP | GO:2001141 | regulation of RNA biosynthetic process | IEP | Predicted GO |
| InterPro domains | Description | Start | Stop |
| IPR013497 | Topo_IA_cen | 3 | 155 |
