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  5. MA_10430527g0010

MA_10430527g0010


Description : (at3g48190 : 479.0) encodes a homolog of the human ATM gene, which is mutated in ataxia telangiectasia, a chromosome instability disorder. Characterization of mutants suggest a role in repairing DNA in response to ionizing radiation as well as during meiosis. The protein has kinase domains and shows kinase activity in orthologs. There is also evidence that ATM might be involved in the telomerase-independent process known as Alternative Lengthening of Telomeres.; ataxia-telangiectasia mutated (ATM); FUNCTIONS IN: 1-phosphatidylinositol-3-phosphate 5-kinase activity; INVOLVED IN: in 8 processes; LOCATED IN: chloroplast; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidylinositol 3-/4-kinase, catalytic (InterPro:IPR000403), PIK-related kinase, FAT (InterPro:IPR003151), Ataxia-Telangiectasia Mutated (InterPro:IPR015519), PIK-related kinase (InterPro:IPR014009), PWWP (InterPro:IPR000313), PIK-related kinase, FATC (InterPro:IPR003152), Phosphatidylinositol 3/4-kinase, conserved site (InterPro:IPR018936), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: Ataxia telangiectasia-mutated and RAD3-related (TAIR:AT5G40820.1); Has 3479 Blast hits to 3364 proteins in 268 species: Archae - 0; Bacteria - 7; Metazoa - 1400; Fungi - 858; Plants - 531; Viruses - 0; Other Eukaryotes - 683 (source: NCBI BLink). & (q5z987|atr_orysa : 203.0) Serine/threonine-protein kinase ATR (EC 2.7.11.1) - Oryza sativa (Rice) & (reliability: 958.0) & (original description: no original description)


Gene families : OG_42_0006876 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0006876_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_10430527g0010
Cluster HCCA clusters: Cluster_167


Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
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Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence
InterPro domains Description Start Stop
IPR000403 PI3/4_kinase_cat_dom 9 215
IPR003152 FATC_dom 270 299
No external refs found!