MA_10431031g0010

Description : (p36183|enpl_horvu : 730.0) Endoplasmin homolog precursor (GRP94 homolog) - Hordeum vulgare (Barley) & (at4g24190 : 725.0) encodes an ortholog of GRP94, an ER-resident HSP90-like protein and is involved in regulation of meristem size and organization. Single and double mutant analyses suggest that SHD may be required for the correct folding and/or complex formation of CLV proteins. Lines carrying recessive mutations in this locus exhibits expanded shoot meristems, disorganized root meristems, and defective pollen tube elongation. Transcript is detected in all tissues examined and is not induced by heat. Endoplasmin supports the protein secretory pathway and has a role in proliferating tissues.; SHEPHERD (SHD); FUNCTIONS IN: unfolded protein binding, ATP binding; INVOLVED IN: in 8 processes; LOCATED IN: in 6 components; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Chaperone protein htpG (InterPro:IPR001404), Heat shock protein Hsp90, C-terminal (InterPro:IPR020576), Heat shock protein Hsp90, N-terminal (InterPro:IPR020575), Molecular chaperone, heat shock protein, endoplasmin (InterPro:IPR015566), ATPase-like, ATP-binding domain (InterPro:IPR003594), Heat shock protein Hsp90, conserved site (InterPro:IPR019805), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568); BEST Arabidopsis thaliana protein match is: heat shock protein 90.1 (TAIR:AT5G52640.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 1450.0) & (original description: no original description)

Gene families : OG_42_0000360 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000360_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Picea release: MA_10431031g0010
Cluster	HCCA clusters: Cluster_209

Target	Alias	Description	ECC score	Gene Family Method
440901	No alias	Chaperone protein htpG family protein	0.03	Orthogroups_2024-Update
Bradi1g30130	No alias	Chaperone protein htpG family protein	0.02	Orthogroups_2024-Update
Bradi5g02037	No alias	heat shock protein 90.1	0.03	Orthogroups_2024-Update
Cre02.g080650	No alias	Chaperone protein htpG family protein	0.01	Orthogroups_2024-Update
GRMZM2G141931	No alias	Chaperone protein htpG family protein	0.03	Orthogroups_2024-Update
Glyma.14G219700	No alias	Chaperone protein htpG family protein	0.02	Orthogroups_2024-Update
Kfl00416_0110	kfl00416_0110_v1.1	(at4g24190 : 832.0) encodes an ortholog of GRP94, an...	0.03	Orthogroups_2024-Update
Mp1g26610.1	No alias	chaperone (Hsp90)	0.03	Orthogroups_2024-Update
Seita.4G281500.1	No alias	chaperone *(Hsp90)	0.03	Orthogroups_2024-Update
Seita.6G200000.1	No alias	chaperone *(Hsp90)	0.04	Orthogroups_2024-Update
Seita.6G200300.1	No alias	chaperone *(Hsp90)	0.04	Orthogroups_2024-Update
Solyc07g065840	No alias	molecular chaperone Hsp90-2	0.03	Orthogroups_2024-Update
Sopen04g035180	No alias	Hsp90 protein	0.02	Orthogroups_2024-Update
evm.model.contig_3455.1	No alias	(at4g24190 : 514.0) encodes an ortholog of GRP94, an...	0.02	Orthogroups_2024-Update
evm.model.contig_601.1	No alias	(at5g56030 : 902.0) A member of heat shock protein 90...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
BP	GO:0006457	protein folding	IEA	InterProScan predictions
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0051082	unfolded protein binding	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Predicted GO
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	Predicted GO
BP	GO:0000398	mRNA splicing, via spliceosome	IEP	Predicted GO
BP	GO:0002682	regulation of immune system process	IEP	Predicted GO
BP	GO:0002831	regulation of response to biotic stimulus	IEP	Predicted GO
MF	GO:0004421	hydroxymethylglutaryl-CoA synthase activity	IEP	Predicted GO
MF	GO:0005509	calcium ion binding	IEP	Predicted GO
CC	GO:0005681	spliceosomal complex	IEP	Predicted GO
CC	GO:0005783	endoplasmic reticulum	IEP	Predicted GO
BP	GO:0006081	cellular aldehyde metabolic process	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
BP	GO:0006720	isoprenoid metabolic process	IEP	Predicted GO
MF	GO:0008081	phosphoric diester hydrolase activity	IEP	Predicted GO
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Predicted GO
BP	GO:0008380	RNA splicing	IEP	Predicted GO
BP	GO:0008610	lipid biosynthetic process	IEP	Predicted GO
BP	GO:0008654	phospholipid biosynthetic process	IEP	Predicted GO
BP	GO:0009240	isopentenyl diphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009892	negative regulation of metabolic process	IEP	Predicted GO
BP	GO:0010112	regulation of systemic acquired resistance	IEP	Predicted GO
BP	GO:0010468	regulation of gene expression	IEP	Predicted GO
BP	GO:0010605	negative regulation of macromolecule metabolic process	IEP	Predicted GO
BP	GO:0010629	negative regulation of gene expression	IEP	Predicted GO
BP	GO:0016458	gene silencing	IEP	Predicted GO
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	Predicted GO
MF	GO:0016726	oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor	IEP	Predicted GO
BP	GO:0019222	regulation of metabolic process	IEP	Predicted GO
BP	GO:0019288	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEP	Predicted GO
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	IEP	Predicted GO
CC	GO:0031011	Ino80 complex	IEP	Predicted GO
BP	GO:0031047	gene silencing by RNA	IEP	Predicted GO
BP	GO:0031347	regulation of defense response	IEP	Predicted GO
BP	GO:0032101	regulation of response to external stimulus	IEP	Predicted GO
CC	GO:0033202	DNA helicase complex	IEP	Predicted GO
MF	GO:0043565	sequence-specific DNA binding	IEP	Predicted GO
BP	GO:0043900	regulation of multi-organism process	IEP	Predicted GO
BP	GO:0044255	cellular lipid metabolic process	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0044454	nuclear chromosome part	IEP	Predicted GO
BP	GO:0045088	regulation of innate immune response	IEP	Predicted GO
BP	GO:0046490	isopentenyl diphosphate metabolic process	IEP	Predicted GO
MF	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	IEP	Predicted GO
BP	GO:0048583	regulation of response to stimulus	IEP	Predicted GO
BP	GO:0050776	regulation of immune response	IEP	Predicted GO
BP	GO:0050789	regulation of biological process	IEP	Predicted GO
BP	GO:0050992	dimethylallyl diphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0050993	dimethylallyl diphosphate metabolic process	IEP	Predicted GO
MF	GO:0051745	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	IEP	Predicted GO
BP	GO:0060255	regulation of macromolecule metabolic process	IEP	Predicted GO
BP	GO:0065007	biological regulation	IEP	Predicted GO
CC	GO:0070603	SWI/SNF superfamily-type complex	IEP	Predicted GO
BP	GO:0080134	regulation of response to stress	IEP	Predicted GO
CC	GO:0097346	INO80-type complex	IEP	Predicted GO
CC	GO:1904949	ATPase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003594	HATPase_C	104	259
IPR001404	Hsp90_fam	262	538

External Links

No external refs found!

MA_10431031g0010

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation