MA_10433454g0020


Description : (p68173|sahh_tobac : 844.0) Adenosylhomocysteinase (EC 3.3.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase) (Cytokinin-binding protein CBP57) - Nicotiana tabacum (Common tobacco) & (at4g13940 : 837.0) Encodes a S-adenosyl-L-homocysteine hydrolase required for DNA methylation-dependent gene silencing.; HOMOLOGY-DEPENDENT GENE SILENCING 1 (HOG1); FUNCTIONS IN: adenosylhomocysteinase activity; INVOLVED IN: methylation-dependent chromatin silencing, one-carbon metabolic process, posttranscriptional gene silencing, embryo development ending in seed dormancy; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 34 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: S-adenosyl-L-homocysteine hydrolase (InterPro:IPR000043), S-adenosyl-L-homocysteine hydrolase, conserved site (InterPro:IPR020082), NAD(P)-binding domain (InterPro:IPR016040), S-adenosyl-L-homocysteine hydrolase, NAD binding (InterPro:IPR015878); BEST Arabidopsis thaliana protein match is: S-adenosyl-l-homocysteine (SAH) hydrolase 2 (TAIR:AT3G23810.1); Has 6788 Blast hits to 6786 proteins in 1444 species: Archae - 223; Bacteria - 2243; Metazoa - 514; Fungi - 135; Plants - 203; Viruses - 0; Other Eukaryotes - 3470 (source: NCBI BLink). & (reliability: 1674.0) & (original description: no original description)


Gene families : OG_42_0003165 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003165_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_10433454g0020
Cluster HCCA clusters: Cluster_229

Target Alias Description ECC score Gene Family Method Actions
158886 No alias S-adenosyl-L-homocysteine hydrolase 0.02 Orthogroups_2024-Update
Brara.A02613.1 No alias S-adenosyl homocysteine hydrolase & EC_3.3 hydrolase... 0.03 Orthogroups_2024-Update
Brara.C03924.1 No alias S-adenosyl homocysteine hydrolase & EC_3.3 hydrolase... 0.04 Orthogroups_2024-Update
Brara.G00699.1 No alias S-adenosyl homocysteine hydrolase & EC_3.3 hydrolase... 0.03 Orthogroups_2024-Update
Cre03.g204250 No alias S-adenosyl-L-homocysteine hydrolase 0.02 Orthogroups_2024-Update
Potri.017G059400 No alias S-adenosyl-L-homocysteine hydrolase 0.03 Orthogroups_2024-Update
Seita.1G277600.1 No alias S-adenosyl homocysteine hydrolase & EC_3.3 hydrolase... 0.03 Orthogroups_2024-Update
Solyc12g098500 No alias Adenosylhomocysteinase (AHRD V3.3 *** K4DHM3_SOLLC) 0.03 Orthogroups_2024-Update
evm.model.tig00020537.69 No alias (at4g13940 : 452.0) Encodes a S-adenosyl-L-homocysteine... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
BP GO:0000096 sulfur amino acid metabolic process IEP Predicted GO
BP GO:0000097 sulfur amino acid biosynthetic process IEP Predicted GO
MF GO:0003684 damaged DNA binding IEP Predicted GO
MF GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity IEP Predicted GO
MF GO:0003871 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity IEP Predicted GO
MF GO:0004478 methionine adenosyltransferase activity IEP Predicted GO
MF GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity IEP Predicted GO
MF GO:0004860 protein kinase inhibitor activity IEP Predicted GO
MF GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity IEP Predicted GO
BP GO:0006081 cellular aldehyde metabolic process IEP Predicted GO
BP GO:0006098 pentose-phosphate shunt IEP Predicted GO
BP GO:0006289 nucleotide-excision repair IEP Predicted GO
BP GO:0006520 cellular amino acid metabolic process IEP Predicted GO
BP GO:0006555 methionine metabolic process IEP Predicted GO
BP GO:0006556 S-adenosylmethionine biosynthetic process IEP Predicted GO
BP GO:0006732 coenzyme metabolic process IEP Predicted GO
BP GO:0006739 NADP metabolic process IEP Predicted GO
BP GO:0006790 sulfur compound metabolic process IEP Predicted GO
BP GO:0007050 cell cycle arrest IEP Predicted GO
MF GO:0008134 transcription factor binding IEP Predicted GO
MF GO:0008172 S-methyltransferase activity IEP Predicted GO
BP GO:0008652 cellular amino acid biosynthetic process IEP Predicted GO
BP GO:0009066 aspartate family amino acid metabolic process IEP Predicted GO
BP GO:0009067 aspartate family amino acid biosynthetic process IEP Predicted GO
BP GO:0009086 methionine biosynthetic process IEP Predicted GO
BP GO:0010498 proteasomal protein catabolic process IEP Predicted GO
BP GO:0016053 organic acid biosynthetic process IEP Predicted GO
BP GO:0016458 gene silencing IEP Predicted GO
MF GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IEP Predicted GO
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups IEP Predicted GO
MF GO:0017025 TBP-class protein binding IEP Predicted GO
MF GO:0019207 kinase regulator activity IEP Predicted GO
MF GO:0019210 kinase inhibitor activity IEP Predicted GO
BP GO:0019682 glyceraldehyde-3-phosphate metabolic process IEP Predicted GO
MF GO:0019887 protein kinase regulator activity IEP Predicted GO
BP GO:0022402 cell cycle process IEP Predicted GO
BP GO:0030163 protein catabolic process IEP Predicted GO
MF GO:0030291 protein serine/threonine kinase inhibitor activity IEP Predicted GO
BP GO:0031047 gene silencing by RNA IEP Predicted GO
MF GO:0042085 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity IEP Predicted GO
BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEP Predicted GO
BP GO:0044272 sulfur compound biosynthetic process IEP Predicted GO
BP GO:0045786 negative regulation of cell cycle IEP Predicted GO
BP GO:0046394 carboxylic acid biosynthetic process IEP Predicted GO
BP GO:0046500 S-adenosylmethionine metabolic process IEP Predicted GO
BP GO:0048519 negative regulation of biological process IEP Predicted GO
BP GO:0048523 negative regulation of cellular process IEP Predicted GO
BP GO:0051156 glucose 6-phosphate metabolic process IEP Predicted GO
BP GO:0051186 cofactor metabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR000043 Adenosylhomocysteinase-like 13 472
IPR015878 Ado_hCys_hydrolase_NAD-bd 228 391
No external refs found!