MA_10435700g0010

Description : (at5g13570 : 378.0) Encodes DCP2 with mRNA decapping activity. DCP2 forms a mRNA decapping complex with DCP1 (At1g08370) and VCS (VARICOSE) (At3g13300). Recombinant DCP2 is enzymatically active in vitro, generating from capped mRNAs m7GDP, and 5Ã-phosphorylated mRNAs. DCP1, DCP2 and VCS colocalize in cytoplasmic loci, which are putative Arabidopsis mRNA processing bodies. Null mutants of DCP1, DCP2, and VCS accumulate capped mRNAs with a reduced degradation rate. These mutants also share a similar lethal phenotype at the seedling cotyledon stage, with disorganized veins, swollen root hairs, and altered epidermal cell morphology. The protein was shown by immunoprecipitation not to interact with DCP1.; decapping 2 (DCP2); CONTAINS InterPro DOMAIN/s: NUDIX hydrolase domain-like (InterPro:IPR015797), Dcp2, box A (InterPro:IPR007722), NUDIX hydrolase domain (InterPro:IPR000086). & (reliability: 756.0) & (original description: no original description)

Gene families : OG_42_0005146 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005146_tree

Sequence : coding (download), protein (download)

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Type	Description	Actions
Neighborhood	Picea release: MA_10435700g0010
Cluster	HCCA clusters: Cluster_148

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003723	RNA binding	IEA	InterProScan predictions
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0016787	hydrolase activity	IEA	InterProScan predictions
MF	GO:0030145	manganese ion binding	IEA	InterProScan predictions
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0001510	RNA methylation	IEP	Predicted GO
MF	GO:0001882	nucleoside binding	IEP	Predicted GO
MF	GO:0001883	purine nucleoside binding	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0003779	actin binding	IEP	Predicted GO
MF	GO:0005198	structural molecule activity	IEP	Predicted GO
MF	GO:0005525	GTP binding	IEP	Predicted GO
MF	GO:0005543	phospholipid binding	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005840	ribosome	IEP	Predicted GO
BP	GO:0006412	translation	IEP	Predicted GO
BP	GO:0006518	peptide metabolic process	IEP	Predicted GO
BP	GO:0007010	cytoskeleton organization	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0009451	RNA modification	IEP	Predicted GO
BP	GO:0016071	mRNA metabolic process	IEP	Predicted GO
BP	GO:0016556	mRNA modification	IEP	Predicted GO
MF	GO:0019001	guanyl nucleotide binding	IEP	Predicted GO
BP	GO:0032259	methylation	IEP	Predicted GO
MF	GO:0032549	ribonucleoside binding	IEP	Predicted GO
MF	GO:0032550	purine ribonucleoside binding	IEP	Predicted GO
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0043043	peptide biosynthetic process	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043228	non-membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043414	macromolecule methylation	IEP	Predicted GO
BP	GO:0043603	cellular amide metabolic process	IEP	Predicted GO
BP	GO:0043604	amide biosynthetic process	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
MF	GO:0051087	chaperone binding	IEP	Predicted GO
BP	GO:0080009	mRNA methylation	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000086	NUDIX_hydrolase_dom	106	224
IPR007722	DCP2_BoxA	20	102

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MA_10435700g0010

Expression Profile

Co-expression Networks

Functional Annotation