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  5. MA_107903g0010

MA_107903g0010


Description : (p31251|ube12_wheat : 1518.0) Ubiquitin-activating enzyme E1 2 - Triticum aestivum (Wheat) & (at2g30110 : 1498.0) Encodes a ubiquitin-activating enzyme (E1), involved in the first step in conjugating multiple ubiquitins to proteins targeted for degradation. Gene is expressed in most tissues examined. Mutant is able to revert the constitutive defense responses phenotype of snc1, which indicates the gene is involved in defense response. It also indicates that ubiquitination plays a role in plant defense signalling.; ubiquitin-activating enzyme 1 (UBA1); FUNCTIONS IN: ubiquitin-protein ligase activity, ubiquitin activating enzyme activity; INVOLVED IN: response to cadmium ion, response to other organism, protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-activating enzyme, E1, active site (InterPro:IPR018074), Ubiquitin-activating enzyme, E1 (InterPro:IPR018075), Ubiquitin-activating enzyme e1, C-terminal (InterPro:IPR018965), Ubiquitin-activating enzyme repeat (InterPro:IPR000127), Ubiquitin-activating enzyme (InterPro:IPR019572), UBA/THIF-type NAD/FAD binding fold (InterPro:IPR000594), Molybdenum cofactor biosynthesis, MoeB (InterPro:IPR009036), NAD(P)-binding domain (InterPro:IPR016040), Ubiquitin-activating enzyme, E1-like (InterPro:IPR000011); BEST Arabidopsis thaliana protein match is: ubiquitin activating enzyme 2 (TAIR:AT5G06460.1); Has 19490 Blast hits to 12603 proteins in 2346 species: Archae - 393; Bacteria - 11015; Metazoa - 2131; Fungi - 1366; Plants - 791; Viruses - 0; Other Eukaryotes - 3794 (source: NCBI BLink). & (reliability: 2996.0) & (original description: no original description)


Gene families : OG_42_0001467 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001467_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_107903g0010
Cluster HCCA clusters: Cluster_59

Target Alias Description ECC score Gene Family Method Actions
At2g30110 No alias UBA1 [Source:UniProtKB/TrEMBL;Acc:A0A178VN59] 0.03 Orthogroups_2024-Update
Bradi1g16680 No alias ubiquitin activating enzyme 2 0.02 Orthogroups_2024-Update
Bradi4g44880 No alias ubiquitin activating enzyme 2 0.03 Orthogroups_2024-Update
Brara.E01311.1 No alias E1 ubiquitin-activating enzyme 0.04 Orthogroups_2024-Update
Cre09.g386400 No alias ubiquitin activating enzyme 2 0.05 Orthogroups_2024-Update
GRMZM2G057441 No alias ubiquitin activating enzyme 2 0.03 Orthogroups_2024-Update
Glyma.11G166100 No alias ubiquitin-activating enzyme 1 0.06 Orthogroups_2024-Update
Kfl00008_0090 kfl00008_0090_v1.1 (p31251|ube12_wheat : 1361.0) Ubiquitin-activating... 0.03 Orthogroups_2024-Update
Kfl00533_0100 kfl00533_0100_v1.1 (p31251|ube12_wheat : 672.0) Ubiquitin-activating enzyme... 0.01 Orthogroups_2024-Update
Mp7g08080.1 No alias ubiquitin-activating E1 protein 0.05 Orthogroups_2024-Update
PSME_00016707-RA No alias (p31251|ube12_wheat : 1493.0) Ubiquitin-activating... 0.07 Orthogroups_2024-Update
Pp1s5_305V6 No alias ubiquitin-activating enzyme 0.03 Orthogroups_2024-Update
Pp1s74_65V6 No alias ubiquitin-activating enzyme 0.02 Orthogroups_2024-Update
Seita.7G331900.1 No alias E1 ubiquitin-activating enzyme 0.06 Orthogroups_2024-Update
Seita.8G019500.1 No alias E1 ubiquitin-activating enzyme 0.07 Orthogroups_2024-Update
Sopen09g011640 No alias ThiF family 0.02 Orthogroups_2024-Update
evm.model.tig00000057.43 No alias (p31251|ube12_wheat : 840.0) Ubiquitin-activating enzyme... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0008641 ubiquitin-like modifier activating enzyme activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0001882 nucleoside binding IEP Predicted GO
MF GO:0001883 purine nucleoside binding IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003743 translation initiation factor activity IEP Predicted GO
MF GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity IEP Predicted GO
MF GO:0005092 GDP-dissociation inhibitor activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
MF GO:0005516 calmodulin binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
MF GO:0005525 GTP binding IEP Predicted GO
CC GO:0005575 cellular_component IEP Predicted GO
CC GO:0005852 eukaryotic translation initiation factor 3 complex IEP Predicted GO
BP GO:0006810 transport IEP Predicted GO
BP GO:0006886 intracellular protein transport IEP Predicted GO
BP GO:0006904 vesicle docking involved in exocytosis IEP Predicted GO
BP GO:0007264 small GTPase mediated signal transduction IEP Predicted GO
BP GO:0007275 multicellular organism development IEP Predicted GO
BP GO:0008104 protein localization IEP Predicted GO
MF GO:0008135 translation factor activity, RNA binding IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0008536 Ran GTPase binding IEP Predicted GO
BP GO:0015031 protein transport IEP Predicted GO
MF GO:0015077 monovalent inorganic cation transmembrane transporter activity IEP Predicted GO
BP GO:0015672 monovalent inorganic cation transport IEP Predicted GO
BP GO:0015833 peptide transport IEP Predicted GO
CC GO:0016021 integral component of membrane IEP Predicted GO
BP GO:0016192 vesicle-mediated transport IEP Predicted GO
MF GO:0016462 pyrophosphatase activity IEP Predicted GO
MF GO:0016651 oxidoreductase activity, acting on NAD(P)H IEP Predicted GO
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEP Predicted GO
MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEP Predicted GO
MF GO:0017016 Ras GTPase binding IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0017111 nucleoside-triphosphatase activity IEP Predicted GO
MF GO:0019001 guanyl nucleotide binding IEP Predicted GO
MF GO:0019899 enzyme binding IEP Predicted GO
BP GO:0022406 membrane docking IEP Predicted GO
CC GO:0030120 vesicle coat IEP Predicted GO
CC GO:0030126 COPI vesicle coat IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
CC GO:0031224 intrinsic component of membrane IEP Predicted GO
MF GO:0031267 small GTPase binding IEP Predicted GO
MF GO:0031369 translation initiation factor binding IEP Predicted GO
BP GO:0032501 multicellular organismal process IEP Predicted GO
BP GO:0032502 developmental process IEP Predicted GO
MF GO:0032549 ribonucleoside binding IEP Predicted GO
MF GO:0032550 purine ribonucleoside binding IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
MF GO:0032561 guanyl ribonucleotide binding IEP Predicted GO
BP GO:0033036 macromolecule localization IEP Predicted GO
CC GO:0033179 proton-transporting V-type ATPase, V0 domain IEP Predicted GO
BP GO:0034220 ion transmembrane transport IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
BP GO:0042886 amide transport IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
CC GO:0044425 membrane part IEP Predicted GO
BP GO:0045184 establishment of protein localization IEP Predicted GO
BP GO:0046907 intracellular transport IEP Predicted GO
BP GO:0048278 vesicle docking IEP Predicted GO
BP GO:0048856 anatomical structure development IEP Predicted GO
MF GO:0051020 GTPase binding IEP Predicted GO
BP GO:0051179 localization IEP Predicted GO
BP GO:0051234 establishment of localization IEP Predicted GO
BP GO:0051640 organelle localization IEP Predicted GO
BP GO:0051641 cellular localization IEP Predicted GO
BP GO:0051649 establishment of localization in cell IEP Predicted GO
BP GO:0071702 organic substance transport IEP Predicted GO
BP GO:0071705 nitrogen compound transport IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
BP GO:0098655 cation transmembrane transport IEP Predicted GO
BP GO:0098660 inorganic ion transmembrane transport IEP Predicted GO
BP GO:0098662 inorganic cation transmembrane transport IEP Predicted GO
BP GO:0140029 exocytic process IEP Predicted GO
BP GO:0140056 organelle localization by membrane tethering IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
InterPro domains Description Start Stop
IPR018965 Ub-activating_enz_E1_C 925 1014
IPR032418 E1_FCCH 191 262
IPR032420 E1_4HB 263 332
IPR019572 UBA_E1_Cys 602 855
IPR000594 ThiF_NAD_FAD-bd 18 401
IPR000594 ThiF_NAD_FAD-bd 415 913
No external refs found!