MA_138894g0010

Description : (at2g47000 : 1332.0) Multidrug resistance P-glycoprotein (MDR/PGP) subfamily of ABC transporters. Functions in the basipetal redirection of auxin from the root tip. Exhibits apolar plasma membrane localization in the root cap and polar localization in tissues above.; ATP binding cassette subfamily B4 (ABCB4); FUNCTIONS IN: xenobiotic-transporting ATPase activity, ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: in 8 processes; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: P-glycoprotein 21 (TAIR:AT3G62150.1); Has 844144 Blast hits to 390751 proteins in 4168 species: Archae - 14748; Bacteria - 659498; Metazoa - 17847; Fungi - 13026; Plants - 10001; Viruses - 45; Other Eukaryotes - 128979 (source: NCBI BLink). & (q6yuu5|mdr_orysa : 778.0) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 2664.0) & (original description: no original description)

Gene families : OG_42_0000040 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000040_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Picea release: MA_138894g0010
Cluster	HCCA clusters: Cluster_218

Target	Alias	Description	ECC score	Gene Family Method
A4A49_02254	No alias	abc transporter b family member 11	0.03	Orthogroups_2024-Update
At3g28345	No alias	ABC transporter B family member 15...	0.03	Orthogroups_2024-Update
Brara.F03055.1	No alias	subfamily ABCB transporter	0.03	Orthogroups_2024-Update
Brara.J00114.1	No alias	subfamily ABCB transporter	0.02	Orthogroups_2024-Update
GRMZM2G004748	No alias	P-glycoprotein 2	0.03	Orthogroups_2024-Update
Glyma.13G118800	No alias	P-glycoprotein 11	0.02	Orthogroups_2024-Update
Glyma.16G078100	No alias	ABC transporter family protein	0.03	Orthogroups_2024-Update
Glyma.17G259100	No alias	P-glycoprotein 13	0.02	Orthogroups_2024-Update
PSME_00016535-RA	No alias	(at3g28860 : 1775.0) Belongs to the family of...	0.03	Orthogroups_2024-Update
PSME_00037351-RA	No alias	(at3g28345 : 1429.0) ABC transporter family protein;...	0.03	Orthogroups_2024-Update
Seita.5G283500.1	No alias	subfamily ABCB transporter	0.03	Orthogroups_2024-Update
Seita.5G283600.1	No alias	subfamily ABCB transporter	0.03	Orthogroups_2024-Update
Sopen02g032160	No alias	ABC transporter transmembrane region	0.03	Orthogroups_2024-Update
Sopen02g032590	No alias	ABC transporter transmembrane region	0.02	Orthogroups_2024-Update
Sopen06g004030	No alias	ABC transporter transmembrane region	0.02	Orthogroups_2024-Update
Sopen06g029310	No alias	ABC transporter	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEA	InterProScan predictions
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003677	DNA binding	IEP	Predicted GO
BP	GO:0005984	disaccharide metabolic process	IEP	Predicted GO
BP	GO:0005991	trehalose metabolic process	IEP	Predicted GO
BP	GO:0005992	trehalose biosynthetic process	IEP	Predicted GO
BP	GO:0006355	regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006364	rRNA processing	IEP	Predicted GO
BP	GO:0006855	drug transmembrane transport	IEP	Predicted GO
BP	GO:0009311	oligosaccharide metabolic process	IEP	Predicted GO
BP	GO:0009312	oligosaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0009889	regulation of biosynthetic process	IEP	Predicted GO
BP	GO:0010468	regulation of gene expression	IEP	Predicted GO
BP	GO:0010556	regulation of macromolecule biosynthetic process	IEP	Predicted GO
MF	GO:0015238	drug transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015291	secondary active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015297	antiporter activity	IEP	Predicted GO
BP	GO:0015893	drug transport	IEP	Predicted GO
BP	GO:0016051	carbohydrate biosynthetic process	IEP	Predicted GO
BP	GO:0016072	rRNA metabolic process	IEP	Predicted GO
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0019222	regulation of metabolic process	IEP	Predicted GO
CC	GO:0030684	preribosome	IEP	Predicted GO
CC	GO:0030688	preribosome, small subunit precursor	IEP	Predicted GO
BP	GO:0031323	regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031326	regulation of cellular biosynthetic process	IEP	Predicted GO
BP	GO:0034637	cellular carbohydrate biosynthetic process	IEP	Predicted GO
BP	GO:0044262	cellular carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0046351	disaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0050789	regulation of biological process	IEP	Predicted GO
BP	GO:0050794	regulation of cellular process	IEP	Predicted GO
BP	GO:0051171	regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051252	regulation of RNA metabolic process	IEP	Predicted GO
BP	GO:0060255	regulation of macromolecule metabolic process	IEP	Predicted GO
BP	GO:0065007	biological regulation	IEP	Predicted GO
BP	GO:0080090	regulation of primary metabolic process	IEP	Predicted GO
BP	GO:1903506	regulation of nucleic acid-templated transcription	IEP	Predicted GO
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:2001141	regulation of RNA biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003439	ABC_transporter-like	977	1126
IPR011527	ABC1_TM_dom	62	214
IPR011527	ABC1_TM_dom	637	907
IPR003439	ABC_transporter-like	284	431

External Links

No external refs found!

MA_138894g0010

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation