MA_18863g0010

Description : (at2g47000 : 769.0) Multidrug resistance P-glycoprotein (MDR/PGP) subfamily of ABC transporters. Functions in the basipetal redirection of auxin from the root tip. Exhibits apolar plasma membrane localization in the root cap and polar localization in tissues above.; ATP binding cassette subfamily B4 (ABCB4); FUNCTIONS IN: xenobiotic-transporting ATPase activity, ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: in 8 processes; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: P-glycoprotein 21 (TAIR:AT3G62150.1); Has 844144 Blast hits to 390751 proteins in 4168 species: Archae - 14748; Bacteria - 659498; Metazoa - 17847; Fungi - 13026; Plants - 10001; Viruses - 45; Other Eukaryotes - 128979 (source: NCBI BLink). & (q6yuu5|mdr_orysa : 473.0) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 1538.0) & (original description: no original description)

Gene families : OG_42_0000040 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000040_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Picea release: MA_18863g0010
Cluster	HCCA clusters: Cluster_6

Target	Alias	Description	ECC score	Gene Family Method
A4A49_39105	No alias	abc transporter b family member 11	0.02	Orthogroups_2024-Update
Bradi2g47337	No alias	ATP binding cassette subfamily B4	0.02	Orthogroups_2024-Update
Brara.I00320.1	No alias	subfamily ABCB transporter	0.05	Orthogroups_2024-Update
GRMZM2G085111	No alias	P-glycoprotein 21	0.02	Orthogroups_2024-Update
GRMZM5G833207	No alias	ATP binding cassette subfamily B4	0.03	Orthogroups_2024-Update
LOC_Os04g54930	No alias	ABC transporter, ATP-binding protein, putative, expressed	0.02	Orthogroups_2024-Update
MA_6870g0010	No alias	(q6yuu5\|mdr_orysa : 1284.0) Putative multidrug...	0.03	Orthogroups_2024-Update
Mp2g11920.1	No alias	subfamily ABCB transporter	0.02	Orthogroups_2024-Update
PSME_00038380-RA	No alias	(q6yuu5\|mdr_orysa : 1204.0) Putative multidrug...	0.03	Orthogroups_2024-Update
Potri.001G139700	No alias	P-glycoprotein 2	0.02	Orthogroups_2024-Update
Potri.006G074100	No alias	ABC transporter family protein	0.03	Orthogroups_2024-Update
Potri.010G003000	No alias	ATP binding cassette subfamily B4	0.03	Orthogroups_2024-Update
Potri.018G087100	No alias	ABC transporter family protein	0.03	Orthogroups_2024-Update
Seita.1G280600.1	No alias	subfamily ABCB transporter	0.04	Orthogroups_2024-Update
Seita.5G189700.1	No alias	subfamily ABCB transporter	0.05	Orthogroups_2024-Update
Seita.5G283600.1	No alias	subfamily ABCB transporter	0.05	Orthogroups_2024-Update
Seita.9G449100.1	No alias	subfamily ABCB transporter	0.02	Orthogroups_2024-Update
Sopen09g003060	No alias	ABC transporter transmembrane region	0.03	Orthogroups_2024-Update
evm.model.tig00000025.1	No alias	(at2g47000 : 429.0) Multidrug resistance P-glycoprotein...	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEA	InterProScan predictions
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000160	phosphorelay signal transduction system	IEP	Predicted GO
MF	GO:0004672	protein kinase activity	IEP	Predicted GO
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006397	mRNA processing	IEP	Predicted GO
BP	GO:0006399	tRNA metabolic process	IEP	Predicted GO
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Predicted GO
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006464	cellular protein modification process	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006793	phosphorus metabolic process	IEP	Predicted GO
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0009987	cellular process	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
BP	GO:0016071	mRNA metabolic process	IEP	Predicted GO
MF	GO:0016301	kinase activity	IEP	Predicted GO
BP	GO:0016310	phosphorylation	IEP	Predicted GO
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Predicted GO
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Predicted GO
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Predicted GO
BP	GO:0035556	intracellular signal transduction	IEP	Predicted GO
BP	GO:0036211	protein modification process	IEP	Predicted GO
BP	GO:0043038	amino acid activation	IEP	Predicted GO
BP	GO:0043039	tRNA aminoacylation	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
BP	GO:0043412	macromolecule modification	IEP	Predicted GO
BP	GO:0044237	cellular metabolic process	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003439	ABC_transporter-like	408	555
IPR011527	ABC1_TM_dom	744	916
IPR011527	ABC1_TM_dom	186	338

External Links

No external refs found!

MA_18863g0010

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation