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  5. MA_19258g0020

MA_19258g0020


Description : (at1g72970 : 305.0) Originally identified as a mutation that causes floral organs to fuse together. About 10-20% of mutants also have defects in ovules. Mutants have reduced fertility most likely as because of fusions that pistil emergence. The protein has similarity to the mandelonitrile lyase family of FAD containing oxidoreductases and is predicted to be secreted (SignalP).It is expressed in all tissue layers of roots, inflorescences, stems, leaves, and flowers and is also expressed in siliques. Expression is highest in inflorescence and flower tissue.Transmission of mutant alleles to the progeny shows non mendelian segregation- a percentage of mutant alleles revert back to a previous parental (e.g. grandparental) wild type allele. It has been suggested that an RNA template driven or other extra-DNA genomic mechanism may be responsible for the non-mendelian inheritance of HTH. Reversion events in alleles at other loci have also been observed to occur in plants with an hth mutant background indicating a genome wide effect.; HOTHEAD (HTH); CONTAINS InterPro DOMAIN/s: Glucose-methanol-choline oxidoreductase, N-terminal (InterPro:IPR000172), Glucose-methanol-choline oxidoreductase (InterPro:IPR012132), Glucose-methanol-choline oxidoreductase, C-terminal (InterPro:IPR007867); BEST Arabidopsis thaliana protein match is: Glucose-methanol-choline (GMC) oxidoreductase family protein (TAIR:AT1G12570.1); Has 1244 Blast hits to 1228 proteins in 249 species: Archae - 2; Bacteria - 759; Metazoa - 27; Fungi - 277; Plants - 135; Viruses - 3; Other Eukaryotes - 41 (source: NCBI BLink). & (reliability: 610.0) & (original description: no original description)


Gene families : OG_42_0000273 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000273_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_19258g0020
Cluster HCCA clusters: Cluster_43

Target Alias Description ECC score Gene Family Method Actions
108291 No alias Glucose-methanol-choline (GMC) oxidoreductase family protein 0.03 Orthogroups_2024-Update
405960 No alias Glucose-methanol-choline (GMC) oxidoreductase family protein 0.02 Orthogroups_2024-Update
427468 No alias Glucose-methanol-choline (GMC) oxidoreductase family protein 0.02 Orthogroups_2024-Update
MA_762g0010 No alias (at1g14190 : 327.0) Glucose-methanol-choline (GMC)... 0.05 Orthogroups_2024-Update
PSME_00032064-RA No alias (at1g12570 : 349.0) Glucose-methanol-choline (GMC)... 0.05 Orthogroups_2024-Update
PSME_00051118-RA No alias (at5g51950 : 373.0) Glucose-methanol-choline (GMC)... 0.04 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEA InterProScan predictions
MF GO:0050660 flavin adenine dinucleotide binding IEA InterProScan predictions
BP GO:0055114 oxidation-reduction process IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0004451 isocitrate lyase activity IEP Predicted GO
MF GO:0010181 FMN binding IEP Predicted GO
MF GO:0016833 oxo-acid-lyase activity IEP Predicted GO
InterPro domains Description Start Stop
IPR000172 GMC_OxRdtase_N 225 349
IPR007867 GMC_OxRtase_C 450 517
IPR007867 GMC_OxRtase_C 409 445
No external refs found!