Description : "(at2g47460 : 187.0) ""MYB12 belongs to subgroup 7 of the R2R3-MYB family. It strongly activates the promoters of chalcone synthase (CHS), flavanone 3-hydroxylase (F3H), flavonol synthase (FLS) and - to a lesser extent - chalcone flavanone isomerase (CHI), but cannot activate the promoters of flavonoid-3'hydroxylase (F3'H) and dihydroflavonol 4-reductase (DF). The activation requires a functional MYB recognition element (MRE). Results from the myb12-1f allele indicate that an activation domain might be present in the C-terminus. Overexpression or knock-out plants do not show any obvious phenotype under greenhouse conditions. Young myb12-ko seedlings contain reduced amounts of flavonoids (quercetin and kaempferol), while seedlings as well as leaves of MYB12-OX plants displayed an increased flavonoid content. They did not show any significant difference in anthocyanin content. Expression of CHS and FLS shows a clear correlation to MYB12 expression levels. CHI and F3H show increased transcript levels in the MYB12-OX lines, but no differences in the knock-out. Even in the absence of functional MYB12, flavonol biosynthesis is not completely absent, suggesting functional redundancy. "" The redundant factors are MYB11 and MYB111 although MYB12 is primarily required for flavonol biosynthesis in roots.; myb domain protein 12 (MYB12); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 11 (TAIR:AT3G62610.1); Has 8833 Blast hits to 8133 proteins in 470 species: Archae - 0; Bacteria - 0; Metazoa - 786; Fungi - 423; Plants - 5965; Viruses - 6; Other Eukaryotes - 1653 (source: NCBI BLink). & (p20026|myb1_horvu : 176.0) Myb-related protein Hv1 - Hordeum vulgare (Barley) & (reliability: 346.0) & (original description: no original description)"
Gene families : OG_42_0000002 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_21440g0010 | |
Cluster | HCCA clusters: Cluster_109 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
A4A49_12817 | No alias | myb-related protein pp2 | 0.02 | Orthogroups_2024-Update | |
A4A49_19591 | No alias | myb-related protein myb4 | 0.02 | Orthogroups_2024-Update | |
A4A49_26801 | No alias | transcription factor myb3 | 0.02 | Orthogroups_2024-Update | |
At1g18570 | No alias | Transcription factor MYB51... | 0.03 | Orthogroups_2024-Update | |
At1g74080 | No alias | Transcription factor MYB122... | 0.03 | Orthogroups_2024-Update | |
At3g12720 | No alias | AT3g12720/MBK21_8 [Source:UniProtKB/TrEMBL;Acc:Q9LTW2] | 0.03 | Orthogroups_2024-Update | |
At4g09460 | No alias | Transcription repressor MYB6... | 0.03 | Orthogroups_2024-Update | |
At5g14750 | No alias | WER1 [Source:UniProtKB/TrEMBL;Acc:A0A178UJM1] | 0.02 | Orthogroups_2024-Update | |
At5g35550 | No alias | Duplicated homeodomain-like superfamily protein... | 0.03 | Orthogroups_2024-Update | |
Bradi4g09900 | No alias | myb domain protein 112 | 0.03 | Orthogroups_2024-Update | |
Brara.B01071.1 | No alias | MYB class-R2R3 transcription factor | 0.05 | Orthogroups_2024-Update | |
Brara.C03242.1 | No alias | MYB class-R2R3 transcription factor | 0.04 | Orthogroups_2024-Update | |
Brara.F03109.1 | No alias | MYB class-R2R3 subgroup-1 transcription factor | 0.03 | Orthogroups_2024-Update | |
Brara.G00519.1 | No alias | MYB class-R2R3 subgroup-2 transcription factor | 0.04 | Orthogroups_2024-Update | |
Brara.H01124.1 | No alias | MYB class-R2R3 transcription factor | 0.03 | Orthogroups_2024-Update | |
Brara.I03301.1 | No alias | MYB class-R2R3 subgroup-4 transcription factor | 0.02 | Orthogroups_2024-Update | |
Brara.J02139.1 | No alias | MYB class-R2R3 transcription factor | 0.04 | Orthogroups_2024-Update | |
Glyma.03G006600 | No alias | myb domain protein 60 | 0.05 | Orthogroups_2024-Update | |
Glyma.06G160500 | No alias | myb domain protein 4 | 0.02 | Orthogroups_2024-Update | |
Glyma.10G142200 | No alias | myb domain protein 61 | 0.03 | Orthogroups_2024-Update | |
Glyma.12G237500 | No alias | myb domain protein 83 | 0.04 | Orthogroups_2024-Update | |
Glyma.14G069100 | No alias | myb domain protein 4 | 0.03 | Orthogroups_2024-Update | |
Glyma.15G066800 | No alias | MYB-like 102 | 0.03 | Orthogroups_2024-Update | |
Glyma.17G099800 | No alias | myb domain protein 94 | 0.03 | Orthogroups_2024-Update | |
Glyma.18G261400 | No alias | myb domain protein 16 | 0.03 | Orthogroups_2024-Update | |
Glyma.19G222200 | No alias | myb domain protein 55 | 0.03 | Orthogroups_2024-Update | |
MA_19163g0010 | No alias | (p20026|myb1_horvu : 256.0) Myb-related protein Hv1 -... | 0.05 | Orthogroups_2024-Update | |
PSME_00021445-RA | No alias | (at1g22640 : 169.0) MYB-type transcription factor (MYB3)... | 0.03 | Orthogroups_2024-Update | |
PSME_00050915-RA | No alias | (at1g74650 : 283.0) Member of the R2R3 factor gene... | 0.03 | Orthogroups_2024-Update | |
PSME_00051403-RA | No alias | (at1g22640 : 162.0) MYB-type transcription factor (MYB3)... | 0.03 | Orthogroups_2024-Update | |
Potri.001G258700 | No alias | myb domain protein 46 | 0.03 | Orthogroups_2024-Update | |
Potri.001G408700 | No alias | MYB-like 102 | 0.02 | Orthogroups_2024-Update | |
Potri.003G079100 | No alias | myb domain protein 5 | 0.04 | Orthogroups_2024-Update | |
Potri.003G144200 | No alias | myb domain protein 111 | 0.03 | Orthogroups_2024-Update | |
Potri.003G155700 | No alias | myb domain protein 67 | 0.04 | Orthogroups_2024-Update | |
Potri.004G215100 | No alias | myb domain protein 36 | 0.04 | Orthogroups_2024-Update | |
Potri.007G067600 | No alias | myb domain protein 63 | 0.02 | Orthogroups_2024-Update | |
Potri.008G101400 | No alias | myb domain protein 108 | 0.04 | Orthogroups_2024-Update | |
Potri.009G053900 | No alias | myb domain protein 46 | 0.02 | Orthogroups_2024-Update | |
Potri.011G125900 | No alias | MYB-like 102 | 0.02 | Orthogroups_2024-Update | |
Potri.013G149200 | No alias | myb domain protein 14 | 0.03 | Orthogroups_2024-Update | |
Seita.5G398000.1 | No alias | MYB class-R2R3 subgroup-4 transcription factor | 0.04 | Orthogroups_2024-Update | |
Sobic.007G177100.1 | No alias | MYB class-R2R3 subgroup-4 transcription factor | 0.03 | Orthogroups_2024-Update | |
Sopen10g025190 | No alias | Myb-like DNA-binding domain | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0000166 | nucleotide binding | IEP | Predicted GO |
MF | GO:0003723 | RNA binding | IEP | Predicted GO |
MF | GO:0004721 | phosphoprotein phosphatase activity | IEP | Predicted GO |
BP | GO:0006793 | phosphorus metabolic process | IEP | Predicted GO |
BP | GO:0006796 | phosphate-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0007165 | signal transduction | IEP | Predicted GO |
MF | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity | IEP | Predicted GO |
BP | GO:0016311 | dephosphorylation | IEP | Predicted GO |
MF | GO:0016788 | hydrolase activity, acting on ester bonds | IEP | Predicted GO |
MF | GO:0016791 | phosphatase activity | IEP | Predicted GO |
MF | GO:0017076 | purine nucleotide binding | IEP | Predicted GO |
MF | GO:0030554 | adenyl nucleotide binding | IEP | Predicted GO |
MF | GO:0032553 | ribonucleotide binding | IEP | Predicted GO |
MF | GO:0032555 | purine ribonucleotide binding | IEP | Predicted GO |
MF | GO:0032559 | adenyl ribonucleotide binding | IEP | Predicted GO |
MF | GO:0036094 | small molecule binding | IEP | Predicted GO |
MF | GO:0043168 | anion binding | IEP | Predicted GO |
MF | GO:0043531 | ADP binding | IEP | Predicted GO |
MF | GO:0097159 | organic cyclic compound binding | IEP | Predicted GO |
MF | GO:0097367 | carbohydrate derivative binding | IEP | Predicted GO |
MF | GO:1901265 | nucleoside phosphate binding | IEP | Predicted GO |
MF | GO:1901363 | heterocyclic compound binding | IEP | Predicted GO |
No external refs found! |