MA_21440g0010


Description : "(at2g47460 : 187.0) ""MYB12 belongs to subgroup 7 of the R2R3-MYB family. It strongly activates the promoters of chalcone synthase (CHS), flavanone 3-hydroxylase (F3H), flavonol synthase (FLS) and - to a lesser extent - chalcone flavanone isomerase (CHI), but cannot activate the promoters of flavonoid-3'hydroxylase (F3'H) and dihydroflavonol 4-reductase (DF). The activation requires a functional MYB recognition element (MRE). Results from the myb12-1f allele indicate that an activation domain might be present in the C-terminus. Overexpression or knock-out plants do not show any obvious phenotype under greenhouse conditions. Young myb12-ko seedlings contain reduced amounts of flavonoids (quercetin and kaempferol), while seedlings as well as leaves of MYB12-OX plants displayed an increased flavonoid content. They did not show any significant difference in anthocyanin content. Expression of CHS and FLS shows a clear correlation to MYB12 expression levels. CHI and F3H show increased transcript levels in the MYB12-OX lines, but no differences in the knock-out. Even in the absence of functional MYB12, flavonol biosynthesis is not completely absent, suggesting functional redundancy. "" The redundant factors are MYB11 and MYB111 although MYB12 is primarily required for flavonol biosynthesis in roots.; myb domain protein 12 (MYB12); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 11 (TAIR:AT3G62610.1); Has 8833 Blast hits to 8133 proteins in 470 species: Archae - 0; Bacteria - 0; Metazoa - 786; Fungi - 423; Plants - 5965; Viruses - 6; Other Eukaryotes - 1653 (source: NCBI BLink). & (p20026|myb1_horvu : 176.0) Myb-related protein Hv1 - Hordeum vulgare (Barley) & (reliability: 346.0) & (original description: no original description)"


Gene families : OG_42_0000002 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_21440g0010
Cluster HCCA clusters: Cluster_109

Target Alias Description ECC score Gene Family Method Actions
A4A49_12817 No alias myb-related protein pp2 0.02 Orthogroups_2024-Update
A4A49_19591 No alias myb-related protein myb4 0.02 Orthogroups_2024-Update
A4A49_26801 No alias transcription factor myb3 0.02 Orthogroups_2024-Update
At1g18570 No alias Transcription factor MYB51... 0.03 Orthogroups_2024-Update
At1g74080 No alias Transcription factor MYB122... 0.03 Orthogroups_2024-Update
At3g12720 No alias AT3g12720/MBK21_8 [Source:UniProtKB/TrEMBL;Acc:Q9LTW2] 0.03 Orthogroups_2024-Update
At4g09460 No alias Transcription repressor MYB6... 0.03 Orthogroups_2024-Update
At5g14750 No alias WER1 [Source:UniProtKB/TrEMBL;Acc:A0A178UJM1] 0.02 Orthogroups_2024-Update
At5g35550 No alias Duplicated homeodomain-like superfamily protein... 0.03 Orthogroups_2024-Update
Bradi4g09900 No alias myb domain protein 112 0.03 Orthogroups_2024-Update
Brara.B01071.1 No alias MYB class-R2R3 transcription factor 0.05 Orthogroups_2024-Update
Brara.C03242.1 No alias MYB class-R2R3 transcription factor 0.04 Orthogroups_2024-Update
Brara.F03109.1 No alias MYB class-R2R3 subgroup-1 transcription factor 0.03 Orthogroups_2024-Update
Brara.G00519.1 No alias MYB class-R2R3 subgroup-2 transcription factor 0.04 Orthogroups_2024-Update
Brara.H01124.1 No alias MYB class-R2R3 transcription factor 0.03 Orthogroups_2024-Update
Brara.I03301.1 No alias MYB class-R2R3 subgroup-4 transcription factor 0.02 Orthogroups_2024-Update
Brara.J02139.1 No alias MYB class-R2R3 transcription factor 0.04 Orthogroups_2024-Update
Glyma.03G006600 No alias myb domain protein 60 0.05 Orthogroups_2024-Update
Glyma.06G160500 No alias myb domain protein 4 0.02 Orthogroups_2024-Update
Glyma.10G142200 No alias myb domain protein 61 0.03 Orthogroups_2024-Update
Glyma.12G237500 No alias myb domain protein 83 0.04 Orthogroups_2024-Update
Glyma.14G069100 No alias myb domain protein 4 0.03 Orthogroups_2024-Update
Glyma.15G066800 No alias MYB-like 102 0.03 Orthogroups_2024-Update
Glyma.17G099800 No alias myb domain protein 94 0.03 Orthogroups_2024-Update
Glyma.18G261400 No alias myb domain protein 16 0.03 Orthogroups_2024-Update
Glyma.19G222200 No alias myb domain protein 55 0.03 Orthogroups_2024-Update
MA_19163g0010 No alias (p20026|myb1_horvu : 256.0) Myb-related protein Hv1 -... 0.05 Orthogroups_2024-Update
PSME_00021445-RA No alias (at1g22640 : 169.0) MYB-type transcription factor (MYB3)... 0.03 Orthogroups_2024-Update
PSME_00050915-RA No alias (at1g74650 : 283.0) Member of the R2R3 factor gene... 0.03 Orthogroups_2024-Update
PSME_00051403-RA No alias (at1g22640 : 162.0) MYB-type transcription factor (MYB3)... 0.03 Orthogroups_2024-Update
Potri.001G258700 No alias myb domain protein 46 0.03 Orthogroups_2024-Update
Potri.001G408700 No alias MYB-like 102 0.02 Orthogroups_2024-Update
Potri.003G079100 No alias myb domain protein 5 0.04 Orthogroups_2024-Update
Potri.003G144200 No alias myb domain protein 111 0.03 Orthogroups_2024-Update
Potri.003G155700 No alias myb domain protein 67 0.04 Orthogroups_2024-Update
Potri.004G215100 No alias myb domain protein 36 0.04 Orthogroups_2024-Update
Potri.007G067600 No alias myb domain protein 63 0.02 Orthogroups_2024-Update
Potri.008G101400 No alias myb domain protein 108 0.04 Orthogroups_2024-Update
Potri.009G053900 No alias myb domain protein 46 0.02 Orthogroups_2024-Update
Potri.011G125900 No alias MYB-like 102 0.02 Orthogroups_2024-Update
Potri.013G149200 No alias myb domain protein 14 0.03 Orthogroups_2024-Update
Seita.5G398000.1 No alias MYB class-R2R3 subgroup-4 transcription factor 0.04 Orthogroups_2024-Update
Sobic.007G177100.1 No alias MYB class-R2R3 subgroup-4 transcription factor 0.03 Orthogroups_2024-Update
Sopen10g025190 No alias Myb-like DNA-binding domain 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0004721 phosphoprotein phosphatase activity IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0007165 signal transduction IEP Predicted GO
MF GO:0008138 protein tyrosine/serine/threonine phosphatase activity IEP Predicted GO
BP GO:0016311 dephosphorylation IEP Predicted GO
MF GO:0016788 hydrolase activity, acting on ester bonds IEP Predicted GO
MF GO:0016791 phosphatase activity IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
MF GO:0043531 ADP binding IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
InterPro domains Description Start Stop
IPR001005 SANT/Myb 72 112
IPR001005 SANT/Myb 14 61
No external refs found!