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- MA_321559g0010
MA_321559g0010
Description : (o49914|mloh1_orysa : 163.0) MLO protein homolog 1 (OsMLO1) - Oryza sativa (Rice) & (at1g11310 : 150.0) A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO2 belongs to the clade IV, with AtMLO3, AtMLO6 and AtMLO12. The gene is expressed during early seedling growth, in roots, in vascular system of cotyledons and young leaves,and in fruit abscission zone; it was not expressed in anthers and pollen, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s). mlo resistance in A. thaliana does not involve the signaling molecules ethylene, jasmonic acid or salicylic acid, but requires a syntaxin, glycosyl hydrolase and ABC transporter.; MILDEW RESISTANCE LOCUS O 2 (MLO2); FUNCTIONS IN: calmodulin binding; INVOLVED IN: defense response to fungus, incompatible interaction, cell death, response to fungus, negative regulation of defense response, defense response; LOCATED IN: plasma membrane; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT1G61560.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 300.0) & (original description: no original description)
Expression Profile
Attention: This gene has low abundance.
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
| Type | Description | Actions |
| Neighborhood | Picea release: MA_321559g0010 | |
| Cluster | HCCA clusters: Cluster_210 | |
Expression Context Conservation (ECC)
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
| 85054 | No alias | Seven transmembrane MLO family protein | 0.03 | Orthogroups_2024-Update | |
| At2g17430 | No alias | MLO-like protein 7 [Source:UniProtKB/Swiss-Prot;Acc:O22752] | 0.03 | Orthogroups_2024-Update | |
| At2g44110 | No alias | MLO-like protein [Source:UniProtKB/TrEMBL;Acc:A0A178VQX0] | 0.03 | Orthogroups_2024-Update | |
| Brara.H02718.1 | No alias | disease resistance mediator *(MLO2/6/12) of Systemic... | 0.03 | Orthogroups_2024-Update | |
| Brara.I01026.1 | No alias | regulatory protein *(MLO) of pollen tube guidance | 0.03 | Orthogroups_2024-Update | |
| Glyma.03G093600 | No alias | Seven transmembrane MLO family protein | 0.03 | Orthogroups_2024-Update | |
| HORVU3Hr1G090450.3 | No alias | Unknown function | 0.03 | Orthogroups_2024-Update | |
| PSME_00015673-RA | No alias | (at1g11310 : 477.0) A member of a large family of... | 0.03 | Orthogroups_2024-Update | |
| Pp1s60_220V6 | No alias | calmodulin binding | 0.02 | Orthogroups_2024-Update | |
| Solyc02g083720 | No alias | MLO-like protein (AHRD V3.3 *** K4BAP0_SOLLC) | 0.03 | Orthogroups_2024-Update | |
| Solyc03g095650 | No alias | MLO-like protein (AHRD V3.3 *** K4BIY8_SOLLC) | 0.02 | Orthogroups_2024-Update | |
| Sopen01g044960 | No alias | Mlo family | 0.03 | Orthogroups_2024-Update | |
Functional Annotation
| Type | GO Term | Name | Evidence | Source |
| CC | GO:0005575 | cellular_component | None | Extended |
| BP | GO:0006950 | response to stress | None | Extended |
| BP | GO:0006952 | defense response | IEA | InterProScan predictions |
| BP | GO:0008150 | biological_process | None | Extended |
| CC | GO:0016021 | integral component of membrane | IEA | InterProScan predictions |
| CC | GO:0031224 | intrinsic component of membrane | None | Extended |
| CC | GO:0044425 | membrane part | None | Extended |
| BP | GO:0050896 | response to stimulus | None | Extended |
| Type | GO Term | Name | Evidence | Source |
| BP | GO:0000271 | polysaccharide biosynthetic process | IEP | Predicted GO |
| MF | GO:0003824 | catalytic activity | IEP | Predicted GO |
| MF | GO:0003968 | RNA-directed 5'-3' RNA polymerase activity | IEP | Predicted GO |
| MF | GO:0005506 | iron ion binding | IEP | Predicted GO |
| MF | GO:0005542 | folic acid binding | IEP | Predicted GO |
| BP | GO:0005976 | polysaccharide metabolic process | IEP | Predicted GO |
| BP | GO:0006073 | cellular glucan metabolic process | IEP | Predicted GO |
| MF | GO:0008194 | UDP-glycosyltransferase activity | IEP | Predicted GO |
| BP | GO:0009250 | glucan biosynthetic process | IEP | Predicted GO |
| CC | GO:0016020 | membrane | IEP | Predicted GO |
| BP | GO:0016051 | carbohydrate biosynthetic process | IEP | Predicted GO |
| MF | GO:0016491 | oxidoreductase activity | IEP | Predicted GO |
| MF | GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors | IEP | Predicted GO |
| MF | GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | IEP | Predicted GO |
| MF | GO:0016740 | transferase activity | IEP | Predicted GO |
| MF | GO:0016757 | transferase activity, transferring glycosyl groups | IEP | Predicted GO |
| MF | GO:0016759 | cellulose synthase activity | IEP | Predicted GO |
| MF | GO:0016760 | cellulose synthase (UDP-forming) activity | IEP | Predicted GO |
| MF | GO:0020037 | heme binding | IEP | Predicted GO |
| BP | GO:0030243 | cellulose metabolic process | IEP | Predicted GO |
| BP | GO:0030244 | cellulose biosynthetic process | IEP | Predicted GO |
| MF | GO:0031406 | carboxylic acid binding | IEP | Predicted GO |
| MF | GO:0033218 | amide binding | IEP | Predicted GO |
| BP | GO:0033692 | cellular polysaccharide biosynthetic process | IEP | Predicted GO |
| BP | GO:0034637 | cellular carbohydrate biosynthetic process | IEP | Predicted GO |
| MF | GO:0035251 | UDP-glucosyltransferase activity | IEP | Predicted GO |
| MF | GO:0043177 | organic acid binding | IEP | Predicted GO |
| BP | GO:0044042 | glucan metabolic process | IEP | Predicted GO |
| BP | GO:0044262 | cellular carbohydrate metabolic process | IEP | Predicted GO |
| BP | GO:0044264 | cellular polysaccharide metabolic process | IEP | Predicted GO |
| MF | GO:0046527 | glucosyltransferase activity | IEP | Predicted GO |
| MF | GO:0046906 | tetrapyrrole binding | IEP | Predicted GO |
| MF | GO:0048037 | cofactor binding | IEP | Predicted GO |
| BP | GO:0051273 | beta-glucan metabolic process | IEP | Predicted GO |
| BP | GO:0051274 | beta-glucan biosynthetic process | IEP | Predicted GO |
| BP | GO:0055114 | oxidation-reduction process | IEP | Predicted GO |
| MF | GO:0072341 | modified amino acid binding | IEP | Predicted GO |
| InterPro domains | Description | Start | Stop |
| IPR004326 | Mlo | 10 | 208 |
