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Description : (at5g65970 : 94.4) A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO10 belongs to the clade III, with AtMLO5, AtMLO7, AtMLO8, and AtMLO9. The gene is expressed in root and cotyledon vascular system, in root-shoot junction and lateral root primordia and in developing siliques, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s; MILDEW RESISTANCE LOCUS O 10 (MLO10); FUNCTIONS IN: calmodulin binding; INVOLVED IN: cell death, defense response; LOCATED IN: integral to membrane, plasma membrane; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: seedling growth, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Mlo-related protein (InterPro:IPR004326); BEST Arabidopsis thaliana protein match is: Seven transmembrane MLO family protein (TAIR:AT2G17430.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (o49873|mloh1_horvu : 94.4) MLO protein homolog 1 - Hordeum vulgare (Barley) & (reliability: 188.8) & (original description: no original description)
Gene families : OG_42_0012261 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0012261_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | Picea release: MA_32823g0010 | |
| Cluster | HCCA clusters: Cluster_226 |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| BP | GO:0006952 | defense response | IEA | InterProScan predictions |
| CC | GO:0016021 | integral component of membrane | IEA | InterProScan predictions |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0008483 | transaminase activity | IEP | Predicted GO |
| MF | GO:0016769 | transferase activity, transferring nitrogenous groups | IEP | Predicted GO |
| MF | GO:0016779 | nucleotidyltransferase activity | IEP | Predicted GO |
| MF | GO:0019842 | vitamin binding | IEP | Predicted GO |
| MF | GO:0030170 | pyridoxal phosphate binding | IEP | Predicted GO |
| MF | GO:0048037 | cofactor binding | IEP | Predicted GO |
| MF | GO:0050662 | coenzyme binding | IEP | Predicted GO |
| MF | GO:0051287 | NAD binding | IEP | Predicted GO |
| MF | GO:0070279 | vitamin B6 binding | IEP | Predicted GO |
| MF | GO:0070569 | uridylyltransferase activity | IEP | Predicted GO |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR004326 | Mlo | 1 | 83 |
| No external refs found! |