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- MA_33469g0010
MA_33469g0010
Description : (at1g15750 : 740.0) Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top help of the embryo during the transition stage of embryogenesis. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background.; TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 1480.0) & (original description: no original description)
Expression Profile
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Co-expression Networks
Type | Description | Actions |
Neighborhood | Picea release: MA_33469g0010 | |
Cluster | HCCA clusters: Cluster_93 | |
Expression Context Conservation (ECC)
Target | Alias | Description | ECC score | Gene Family Method | Actions |
Brara.C03589.1 | No alias | auxin signalling transcriptional co-repressor *(TPL/TPR)... | 0.02 | Orthogroups_2024-Update | |
Glyma.07G028000 | No alias | Transducin family protein / WD-40 repeat family protein | 0.03 | Orthogroups_2024-Update | |
HORVU7Hr1G066930.5 | No alias | transcriptional co-repressor *(TPL/TPR) & auxin... | 0.02 | Orthogroups_2024-Update | |
LOC_Os01g15020 | No alias | lissencephaly type-1-like homology motif, putative, expressed | 0.03 | Orthogroups_2024-Update | |
PSME_00009167-RA | No alias | (at3g16830 : 184.0) TOPLESS-related 2 (TPR2); FUNCTIONS... | 0.02 | Orthogroups_2024-Update | |
Pp1s99_260V6 | No alias | tpl protein binding protein homodimerization... | 0.02 | Orthogroups_2024-Update | |
Solyc01g100050 | No alias | TOPLESS 3 | 0.03 | Orthogroups_2024-Update | |
Solyc03g116750 | No alias | WD-repeat protein, putative (AHRD V3.3 *** B9SMF9_RICCO) | 0.04 | Orthogroups_2024-Update | |
Functional Annotation
Type | GO Term | Name | Evidence | Source |
MF | GO:0003674 | molecular_function | None | Extended |
MF | GO:0005488 | binding | None | Extended |
MF | GO:0005515 | protein binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
MF | GO:0003677 | DNA binding | IEP | Predicted GO |
MF | GO:0003700 | DNA-binding transcription factor activity | IEP | Predicted GO |
BP | GO:0006355 | regulation of transcription, DNA-templated | IEP | Predicted GO |
BP | GO:0006886 | intracellular protein transport | IEP | Predicted GO |
BP | GO:0008104 | protein localization | IEP | Predicted GO |
BP | GO:0009889 | regulation of biosynthetic process | IEP | Predicted GO |
BP | GO:0010468 | regulation of gene expression | IEP | Predicted GO |
BP | GO:0010556 | regulation of macromolecule biosynthetic process | IEP | Predicted GO |
BP | GO:0015031 | protein transport | IEP | Predicted GO |
MF | GO:0015399 | primary active transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0015405 | P-P-bond-hydrolysis-driven transmembrane transporter activity | IEP | Predicted GO |
BP | GO:0015833 | peptide transport | IEP | Predicted GO |
MF | GO:0016887 | ATPase activity | IEP | Predicted GO |
BP | GO:0019219 | regulation of nucleobase-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0019222 | regulation of metabolic process | IEP | Predicted GO |
CC | GO:0030117 | membrane coat | IEP | Predicted GO |
BP | GO:0031123 | RNA 3'-end processing | IEP | Predicted GO |
BP | GO:0031124 | mRNA 3'-end processing | IEP | Predicted GO |
BP | GO:0031323 | regulation of cellular metabolic process | IEP | Predicted GO |
BP | GO:0031326 | regulation of cellular biosynthetic process | IEP | Predicted GO |
BP | GO:0033036 | macromolecule localization | IEP | Predicted GO |
MF | GO:0042623 | ATPase activity, coupled | IEP | Predicted GO |
MF | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | IEP | Predicted GO |
BP | GO:0042886 | amide transport | IEP | Predicted GO |
MF | GO:0043492 | ATPase activity, coupled to movement of substances | IEP | Predicted GO |
MF | GO:0043565 | sequence-specific DNA binding | IEP | Predicted GO |
BP | GO:0045184 | establishment of protein localization | IEP | Predicted GO |
BP | GO:0046907 | intracellular transport | IEP | Predicted GO |
BP | GO:0050789 | regulation of biological process | IEP | Predicted GO |
BP | GO:0050794 | regulation of cellular process | IEP | Predicted GO |
BP | GO:0051171 | regulation of nitrogen compound metabolic process | IEP | Predicted GO |
BP | GO:0051252 | regulation of RNA metabolic process | IEP | Predicted GO |
BP | GO:0051641 | cellular localization | IEP | Predicted GO |
BP | GO:0051649 | establishment of localization in cell | IEP | Predicted GO |
BP | GO:0060255 | regulation of macromolecule metabolic process | IEP | Predicted GO |
BP | GO:0065007 | biological regulation | IEP | Predicted GO |
BP | GO:0071702 | organic substance transport | IEP | Predicted GO |
BP | GO:0071705 | nitrogen compound transport | IEP | Predicted GO |
BP | GO:0080090 | regulation of primary metabolic process | IEP | Predicted GO |
MF | GO:0140110 | transcription regulator activity | IEP | Predicted GO |
BP | GO:1903506 | regulation of nucleic acid-templated transcription | IEP | Predicted GO |
BP | GO:2000112 | regulation of cellular macromolecule biosynthetic process | IEP | Predicted GO |
BP | GO:2001141 | regulation of RNA biosynthetic process | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
IPR001680 | WD40_repeat | 690 | 723 |