MA_33469g0010


Description : (at1g15750 : 740.0) Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top help of the embryo during the transition stage of embryogenesis. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background.; TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 1480.0) & (original description: no original description)


Gene families : OG_42_0000373 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000373_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_33469g0010
Cluster HCCA clusters: Cluster_93

Target Alias Description ECC score Gene Family Method Actions
Brara.C03589.1 No alias auxin signalling transcriptional co-repressor *(TPL/TPR)... 0.02 Orthogroups_2024-Update
Glyma.07G028000 No alias Transducin family protein / WD-40 repeat family protein 0.03 Orthogroups_2024-Update
HORVU7Hr1G066930.5 No alias transcriptional co-repressor *(TPL/TPR) & auxin... 0.02 Orthogroups_2024-Update
LOC_Os01g15020 No alias lissencephaly type-1-like homology motif, putative, expressed 0.03 Orthogroups_2024-Update
PSME_00009167-RA No alias (at3g16830 : 184.0) TOPLESS-related 2 (TPR2); FUNCTIONS... 0.02 Orthogroups_2024-Update
Pp1s99_260V6 No alias tpl protein binding protein homodimerization... 0.02 Orthogroups_2024-Update
Solyc01g100050 No alias TOPLESS 3 0.03 Orthogroups_2024-Update
Solyc03g116750 No alias WD-repeat protein, putative (AHRD V3.3 *** B9SMF9_RICCO) 0.04 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0003677 DNA binding IEP Predicted GO
MF GO:0003700 DNA-binding transcription factor activity IEP Predicted GO
BP GO:0006355 regulation of transcription, DNA-templated IEP Predicted GO
BP GO:0006886 intracellular protein transport IEP Predicted GO
BP GO:0008104 protein localization IEP Predicted GO
BP GO:0009889 regulation of biosynthetic process IEP Predicted GO
BP GO:0010468 regulation of gene expression IEP Predicted GO
BP GO:0010556 regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0015031 protein transport IEP Predicted GO
MF GO:0015399 primary active transmembrane transporter activity IEP Predicted GO
MF GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity IEP Predicted GO
BP GO:0015833 peptide transport IEP Predicted GO
MF GO:0016887 ATPase activity IEP Predicted GO
BP GO:0019219 regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0019222 regulation of metabolic process IEP Predicted GO
CC GO:0030117 membrane coat IEP Predicted GO
BP GO:0031123 RNA 3'-end processing IEP Predicted GO
BP GO:0031124 mRNA 3'-end processing IEP Predicted GO
BP GO:0031323 regulation of cellular metabolic process IEP Predicted GO
BP GO:0031326 regulation of cellular biosynthetic process IEP Predicted GO
BP GO:0033036 macromolecule localization IEP Predicted GO
MF GO:0042623 ATPase activity, coupled IEP Predicted GO
MF GO:0042626 ATPase activity, coupled to transmembrane movement of substances IEP Predicted GO
BP GO:0042886 amide transport IEP Predicted GO
MF GO:0043492 ATPase activity, coupled to movement of substances IEP Predicted GO
MF GO:0043565 sequence-specific DNA binding IEP Predicted GO
BP GO:0045184 establishment of protein localization IEP Predicted GO
BP GO:0046907 intracellular transport IEP Predicted GO
BP GO:0050789 regulation of biological process IEP Predicted GO
BP GO:0050794 regulation of cellular process IEP Predicted GO
BP GO:0051171 regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051252 regulation of RNA metabolic process IEP Predicted GO
BP GO:0051641 cellular localization IEP Predicted GO
BP GO:0051649 establishment of localization in cell IEP Predicted GO
BP GO:0060255 regulation of macromolecule metabolic process IEP Predicted GO
BP GO:0065007 biological regulation IEP Predicted GO
BP GO:0071702 organic substance transport IEP Predicted GO
BP GO:0071705 nitrogen compound transport IEP Predicted GO
BP GO:0080090 regulation of primary metabolic process IEP Predicted GO
MF GO:0140110 transcription regulator activity IEP Predicted GO
BP GO:1903506 regulation of nucleic acid-templated transcription IEP Predicted GO
BP GO:2000112 regulation of cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:2001141 regulation of RNA biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR001680 WD40_repeat 690 723
No external refs found!