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Description : (at1g15750 : 436.0) Encodes a protein with several WD40 repeats at the C-terminus and predicted protein-protein interaction domains at the N-terminus. Together with the TOPLESS-RELATED PROTEINS (TPRs), it is thought to be involved in transcriptional repression of root-promoting genes in the top help of the embryo during the transition stage of embryogenesis. The ability of IAA12 to repress transcription is diminished in a tpl-1 mutant background.; TOPLESS (TPL); FUNCTIONS IN: protein binding, transcription repressor activity, protein homodimerization activity; INVOLVED IN: xylem and phloem pattern formation, response to auxin stimulus, primary shoot apical meristem specification, jasmonic acid mediated signaling pathway; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), CTLH, C-terminal LisH motif (InterPro:IPR006595), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: TOPLESS-related 1 (TAIR:AT1G80490.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 872.0) & (original description: no original description)
Gene families : OG_42_0000373 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000373_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | Picea release: MA_366520g0010 | |
| Cluster | HCCA clusters: Cluster_140 |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
No GO annotation available for this sequence |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0004057 | arginyltransferase activity | IEP | Predicted GO |
| MF | GO:0004146 | dihydrofolate reductase activity | IEP | Predicted GO |
| MF | GO:0004347 | glucose-6-phosphate isomerase activity | IEP | Predicted GO |
| MF | GO:0004812 | aminoacyl-tRNA ligase activity | IEP | Predicted GO |
| MF | GO:0004843 | thiol-dependent ubiquitin-specific protease activity | IEP | Predicted GO |
| MF | GO:0005509 | calcium ion binding | IEP | Predicted GO |
| CC | GO:0005694 | chromosome | IEP | Predicted GO |
| CC | GO:0005783 | endoplasmic reticulum | IEP | Predicted GO |
| BP | GO:0005996 | monosaccharide metabolic process | IEP | Predicted GO |
| BP | GO:0006006 | glucose metabolic process | IEP | Predicted GO |
| BP | GO:0006081 | cellular aldehyde metabolic process | IEP | Predicted GO |
| BP | GO:0006082 | organic acid metabolic process | IEP | Predicted GO |
| BP | GO:0006090 | pyruvate metabolic process | IEP | Predicted GO |
| BP | GO:0006094 | gluconeogenesis | IEP | Predicted GO |
| BP | GO:0006399 | tRNA metabolic process | IEP | Predicted GO |
| BP | GO:0006418 | tRNA aminoacylation for protein translation | IEP | Predicted GO |
| BP | GO:0006457 | protein folding | IEP | Predicted GO |
| BP | GO:0006520 | cellular amino acid metabolic process | IEP | Predicted GO |
| BP | GO:0006575 | cellular modified amino acid metabolic process | IEP | Predicted GO |
| BP | GO:0006725 | cellular aromatic compound metabolic process | IEP | Predicted GO |
| BP | GO:0006732 | coenzyme metabolic process | IEP | Predicted GO |
| BP | GO:0006760 | folic acid-containing compound metabolic process | IEP | Predicted GO |
| BP | GO:0006891 | intra-Golgi vesicle-mediated transport | IEP | Predicted GO |
| MF | GO:0008144 | drug binding | IEP | Predicted GO |
| MF | GO:0008483 | transaminase activity | IEP | Predicted GO |
| BP | GO:0008654 | phospholipid biosynthetic process | IEP | Predicted GO |
| BP | GO:0009058 | biosynthetic process | IEP | Predicted GO |
| BP | GO:0009108 | coenzyme biosynthetic process | IEP | Predicted GO |
| BP | GO:0009240 | isopentenyl diphosphate biosynthetic process | IEP | Predicted GO |
| BP | GO:0009396 | folic acid-containing compound biosynthetic process | IEP | Predicted GO |
| BP | GO:0016053 | organic acid biosynthetic process | IEP | Predicted GO |
| MF | GO:0016597 | amino acid binding | IEP | Predicted GO |
| BP | GO:0016598 | protein arginylation | IEP | Predicted GO |
| MF | GO:0016645 | oxidoreductase activity, acting on the CH-NH group of donors | IEP | Predicted GO |
| MF | GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor | IEP | Predicted GO |
| MF | GO:0016725 | oxidoreductase activity, acting on CH or CH2 groups | IEP | Predicted GO |
| MF | GO:0016726 | oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor | IEP | Predicted GO |
| MF | GO:0016743 | carboxyl- or carbamoyltransferase activity | IEP | Predicted GO |
| MF | GO:0016755 | transferase activity, transferring amino-acyl groups | IEP | Predicted GO |
| MF | GO:0016769 | transferase activity, transferring nitrogenous groups | IEP | Predicted GO |
| MF | GO:0016853 | isomerase activity | IEP | Predicted GO |
| MF | GO:0016860 | intramolecular oxidoreductase activity | IEP | Predicted GO |
| MF | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses | IEP | Predicted GO |
| MF | GO:0016874 | ligase activity | IEP | Predicted GO |
| MF | GO:0016875 | ligase activity, forming carbon-oxygen bonds | IEP | Predicted GO |
| BP | GO:0019288 | isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway | IEP | Predicted GO |
| BP | GO:0019318 | hexose metabolic process | IEP | Predicted GO |
| BP | GO:0019319 | hexose biosynthetic process | IEP | Predicted GO |
| BP | GO:0019637 | organophosphate metabolic process | IEP | Predicted GO |
| BP | GO:0019682 | glyceraldehyde-3-phosphate metabolic process | IEP | Predicted GO |
| BP | GO:0019752 | carboxylic acid metabolic process | IEP | Predicted GO |
| MF | GO:0019842 | vitamin binding | IEP | Predicted GO |
| MF | GO:0030170 | pyridoxal phosphate binding | IEP | Predicted GO |
| CC | GO:0030173 | integral component of Golgi membrane | IEP | Predicted GO |
| CC | GO:0031228 | intrinsic component of Golgi membrane | IEP | Predicted GO |
| CC | GO:0031300 | intrinsic component of organelle membrane | IEP | Predicted GO |
| CC | GO:0031301 | integral component of organelle membrane | IEP | Predicted GO |
| MF | GO:0031406 | carboxylic acid binding | IEP | Predicted GO |
| BP | GO:0032787 | monocarboxylic acid metabolic process | IEP | Predicted GO |
| BP | GO:0034660 | ncRNA metabolic process | IEP | Predicted GO |
| MF | GO:0036094 | small molecule binding | IEP | Predicted GO |
| BP | GO:0042398 | cellular modified amino acid biosynthetic process | IEP | Predicted GO |
| BP | GO:0042558 | pteridine-containing compound metabolic process | IEP | Predicted GO |
| BP | GO:0042559 | pteridine-containing compound biosynthetic process | IEP | Predicted GO |
| BP | GO:0043038 | amino acid activation | IEP | Predicted GO |
| BP | GO:0043039 | tRNA aminoacylation | IEP | Predicted GO |
| MF | GO:0043167 | ion binding | IEP | Predicted GO |
| MF | GO:0043168 | anion binding | IEP | Predicted GO |
| MF | GO:0043177 | organic acid binding | IEP | Predicted GO |
| BP | GO:0043436 | oxoacid metabolic process | IEP | Predicted GO |
| BP | GO:0044248 | cellular catabolic process | IEP | Predicted GO |
| BP | GO:0044281 | small molecule metabolic process | IEP | Predicted GO |
| BP | GO:0044283 | small molecule biosynthetic process | IEP | Predicted GO |
| CC | GO:0044431 | Golgi apparatus part | IEP | Predicted GO |
| BP | GO:0046364 | monosaccharide biosynthetic process | IEP | Predicted GO |
| BP | GO:0046394 | carboxylic acid biosynthetic process | IEP | Predicted GO |
| BP | GO:0046483 | heterocycle metabolic process | IEP | Predicted GO |
| BP | GO:0046490 | isopentenyl diphosphate metabolic process | IEP | Predicted GO |
| BP | GO:0046653 | tetrahydrofolate metabolic process | IEP | Predicted GO |
| BP | GO:0046654 | tetrahydrofolate biosynthetic process | IEP | Predicted GO |
| BP | GO:0048193 | Golgi vesicle transport | IEP | Predicted GO |
| BP | GO:0050992 | dimethylallyl diphosphate biosynthetic process | IEP | Predicted GO |
| BP | GO:0050993 | dimethylallyl diphosphate metabolic process | IEP | Predicted GO |
| MF | GO:0051082 | unfolded protein binding | IEP | Predicted GO |
| BP | GO:0051186 | cofactor metabolic process | IEP | Predicted GO |
| BP | GO:0051188 | cofactor biosynthetic process | IEP | Predicted GO |
| MF | GO:0051745 | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity | IEP | Predicted GO |
| MF | GO:0070279 | vitamin B6 binding | IEP | Predicted GO |
| BP | GO:0090407 | organophosphate biosynthetic process | IEP | Predicted GO |
| MF | GO:0140098 | catalytic activity, acting on RNA | IEP | Predicted GO |
| MF | GO:0140101 | catalytic activity, acting on a tRNA | IEP | Predicted GO |
| BP | GO:1901135 | carbohydrate derivative metabolic process | IEP | Predicted GO |
| BP | GO:1901360 | organic cyclic compound metabolic process | IEP | Predicted GO |
No InterPro domains available for this sequence
| No external refs found! |