MA_37876g0020


Description : (at5g13960 : 216.0) Encodes a histone 3 lysine 9 specific methyltransferase involved in the maintenance of DNA methylation. SUVH4/KYP is a SU(VAR)3-9 homolog, a SET domain protein. Known SET domain proteins are involved in epigenetic control of gene expression. There are 10 SUVH genes in Arabidopsis and members of this subfamily of the SET proteins have an additional conserved SRA domain. In kyp mutants, there is a loss of CpNpG methylation. The protein was shown to bind to methylated cytosines of CG, CNG and CNN motifs via its SRA domain but has a preference for the latter two. There is also evidence that KYP/SUVH4 might be involved in the telomerase-independent process known as Alternative Lengthening of Telomeres.; SU(VAR)3-9 homolog 4 (SUVH4); FUNCTIONS IN: double-stranded methylated DNA binding, methyl-CpNpG binding, methyl-CpG binding, histone methyltransferase activity (H3-K9 specific), methyl-CpNpN binding; INVOLVED IN: maintenance of DNA methylation, histone methylation, peptidyl-lysine methylation, histone H3-K9 methylation; LOCATED IN: nucleus; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: SET domain (InterPro:IPR001214), SRA-YDG (InterPro:IPR003105), Pre-SET domain (InterPro:IPR007728), Post-SET domain (InterPro:IPR003616); BEST Arabidopsis thaliana protein match is: SU(VAR)3-9 homolog 6 (TAIR:AT2G22740.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 432.0) & (original description: no original description)


Gene families : OG_42_0000288 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000288_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_37876g0020
Cluster HCCA clusters: Cluster_212

Target Alias Description ECC score Gene Family Method Actions
A4A49_34046 No alias histone-lysine n-methyltransferase, h3 lysine-9 specific suvh5 0.02 Orthogroups_2024-Update
Glyma.04G125500 No alias SU(VAR)3-9 homolog 3 0.05 Orthogroups_2024-Update
Potri.002G237950 No alias SU(VAR)3-9 homolog 4 0.02 Orthogroups_2024-Update
Seita.1G255300.1 No alias EC_2.1 transferase transferring one-carbon group 0.04 Orthogroups_2024-Update
Sobic.003G411400.2 No alias histone H3K9 methyltransferase *(KYP) & EC_2.1... 0.04 Orthogroups_2024-Update
Sopen12g032800 No alias SAD/SRA domain 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0004672 protein kinase activity IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
MF GO:0008289 lipid binding IEP Predicted GO
MF GO:0016301 kinase activity IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
InterPro domains Description Start Stop
IPR003105 SRA_YDG 27 135
No external refs found!