Description : (at5g66750 : 700.0) Protein is similar to SWI2/SNF2 chromatin remodeling proteins. DDM1 is appears to act as a chromatin-remodeling ATPase involved in cytosine methylation in CG and non-CG contexts. Involved in gene silencing and maintenance of DNA methylation and histone methylation. Hypomethylation of many genomic regions occurs in ddm1 mutants, and can cause several phenotypic abnormalities, but some loci, such as BONSAI (At1g73177) can be hypermethylated in ddm1 mutants after several generations, leading to different phenotypes. DDM1 might be involved in establishing a heterochromain boundary. A line expressing an RNAi targeted against DDM1 shows some resistance to agrobacterium-mediated root transformation.; chromatin remodeling 1 (CHR1); FUNCTIONS IN: helicase activity, ATPase activity; INVOLVED IN: methylation-dependent chromatin silencing, DNA mediated transformation, transposition, RNA-mediated; LOCATED IN: nucleosome; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), SNF2-related (InterPro:IPR000330); BEST Arabidopsis thaliana protein match is: chromatin remodeling factor17 (TAIR:AT5G18620.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (q7g8y3|isw2_orysa : 376.0) Probable chromatin remodelling complex ATPase chain (EC 3.6.1.-) (ISW2-like) (Sucrose nonfermenting protein 2 homolog) - Oryza sativa (Rice) & (reliability: 1400.0) & (original description: no original description)
Gene families : OG_42_0000148 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000148_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_42406g0010 | |
Cluster | HCCA clusters: Cluster_85 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
LOC_Os05g05230 | No alias | expressed protein | 0.02 | Orthogroups_2024-Update | |
Pp1s47_44V6 | No alias | chromatin remodeling complex subunit | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005524 | ATP binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003896 | DNA primase activity | IEP | Predicted GO |
MF | GO:0003899 | DNA-directed 5'-3' RNA polymerase activity | IEP | Predicted GO |
MF | GO:0005507 | copper ion binding | IEP | Predicted GO |
BP | GO:0006259 | DNA metabolic process | IEP | Predicted GO |
BP | GO:0006269 | DNA replication, synthesis of RNA primer | IEP | Predicted GO |
MF | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity | IEP | Predicted GO |
MF | GO:0016779 | nucleotidyltransferase activity | IEP | Predicted GO |
MF | GO:0019207 | kinase regulator activity | IEP | Predicted GO |
MF | GO:0019887 | protein kinase regulator activity | IEP | Predicted GO |
BP | GO:0032774 | RNA biosynthetic process | IEP | Predicted GO |
MF | GO:0034062 | 5'-3' RNA polymerase activity | IEP | Predicted GO |
BP | GO:0034654 | nucleobase-containing compound biosynthetic process | IEP | Predicted GO |
MF | GO:0097747 | RNA polymerase activity | IEP | Predicted GO |
MF | GO:0140098 | catalytic activity, acting on RNA | IEP | Predicted GO |
No external refs found! |