MA_428462g0010

Description : (p28002|comt1_medsa : 117.0) Caffeic acid 3-O-methyltransferase (EC 2.1.1.68) (S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase) (COMT) (CAOMT) - Medicago sativa (Alfalfa) & (at5g54160 : 112.0) A caffeic acid/5-hydroxyferulic acid O-methyltransferase. Interacts with 14-4-3 proteins in yeast 2 hybrid assay. AtOMT1 (At5g54160) encodes a flavonol 3Ã-O-methyltransferase that is highly active towards quercetin and myricetin. The substrate specificity identifies the enzyme as flavonol 3Ã-methyltransferase which replaces the former annotation of the gene to encode a caffeic acid/5-hydroxyferulic acid O-methyltransferase; O-methyltransferase 1 (OMT1); FUNCTIONS IN: myricetin 3'-O-methyltransferase activity, quercetin 3-O-methyltransferase activity, caffeate O-methyltransferase activity; INVOLVED IN: lignin biosynthetic process, flavonol biosynthetic process; LOCATED IN: cytosol, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase family protein (TAIR:AT1G77520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 224.0) & (original description: no original description)

Gene families : OG_42_0000016 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000016_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Picea release: MA_428462g0010
Cluster	HCCA clusters: Cluster_239

Target	Alias	Description	ECC score	Gene Family Method
A4A49_36761	No alias	caffeic acid 3-o-methyltransferase 1	0.03	Orthogroups_2024-Update
AC209819.3_FG005	No alias	O-methyltransferase family protein	0.03	Orthogroups_2024-Update
Bradi3g16530	No alias	O-methyltransferase 1	0.02	Orthogroups_2024-Update
Brara.G03470.1	No alias	EC_2.1 transferase transferring one-carbon group	0.03	Orthogroups_2024-Update
Glyma.12G109800	No alias	O-methyltransferase 1	0.04	Orthogroups_2024-Update
HORVU1Hr1G076700.4	No alias	EC_2.1 transferase transferring one-carbon group	0.03	Orthogroups_2024-Update
HORVU6Hr1G092840.2	No alias	EC_2.1 transferase transferring one-carbon group	0.03	Orthogroups_2024-Update
Sobic.001G354400.1	No alias	EC_2.1 transferase transferring one-carbon group	0.03	Orthogroups_2024-Update
Sobic.010G230800.1	No alias	EC_2.1 transferase transferring one-carbon group	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0008168	methyltransferase activity	None	Extended
MF	GO:0008171	O-methyltransferase activity	IEA	InterProScan predictions
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000159	protein phosphatase type 2A complex	IEP	Predicted GO
BP	GO:0000272	polysaccharide catabolic process	IEP	Predicted GO
MF	GO:0003993	acid phosphatase activity	IEP	Predicted GO
MF	GO:0004329	formate-tetrahydrofolate ligase activity	IEP	Predicted GO
CC	GO:0008287	protein serine/threonine phosphatase complex	IEP	Predicted GO
MF	GO:0016160	amylase activity	IEP	Predicted GO
MF	GO:0016161	beta-amylase activity	IEP	Predicted GO
MF	GO:0016651	oxidoreductase activity, acting on NAD(P)H	IEP	Predicted GO
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Predicted GO
MF	GO:0019208	phosphatase regulator activity	IEP	Predicted GO
MF	GO:0019888	protein phosphatase regulator activity	IEP	Predicted GO
MF	GO:0046983	protein dimerization activity	IEP	Predicted GO
MF	GO:0050661	NADP binding	IEP	Predicted GO
MF	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	IEP	Predicted GO
MF	GO:0051287	NAD binding	IEP	Predicted GO
CC	GO:1903293	phosphatase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001077	O_MeTrfase_2	2	139

External Links

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MA_428462g0010

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation