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  5. MA_56692g0010

MA_56692g0010


Description : (o24146|4cl2_tobac : 616.0) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2) (4-coumaroyl-CoA synthase 2) - Nicotiana tabacum (Common tobacco) & (at1g51680 : 570.0) encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. In addition to 4-coumarate, it also converts ferulate. The catalytic efficiency was in the following (descending) order: p-coumaric acid, ferulic acid, caffeic acid and 5-OH-ferulic acid. At4CL1 was unable to use sinapic acid as substrate.; 4-coumarate:CoA ligase 1 (4CL1); CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: 4-coumarate:CoA ligase 2 (TAIR:AT3G21240.1); Has 83069 Blast hits to 75791 proteins in 3772 species: Archae - 1181; Bacteria - 53827; Metazoa - 3457; Fungi - 4480; Plants - 2791; Viruses - 1; Other Eukaryotes - 17332 (source: NCBI BLink). & (reliability: 1140.0) & (original description: no original description)


Gene families : OG_42_0000133 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000133_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_56692g0010
Cluster HCCA clusters: Cluster_79

Target Alias Description ECC score Gene Family Method Actions
A4A49_31911 No alias 4-coumarate--coa ligase-like 6 0.02 Orthogroups_2024-Update
A4A49_40482 No alias 4-coumarate--coa ligase 1 0.03 Orthogroups_2024-Update
At3g21240 No alias Cinnamyl alcohol dehydrogenase... 0.03 Orthogroups_2024-Update
Bradi3g37300 No alias 4-coumarate:CoA ligase 2 0.03 Orthogroups_2024-Update
Brara.A01009.1 No alias Unknown function 0.03 Orthogroups_2024-Update
GRMZM2G328473 No alias AMP-dependent synthetase and ligase family protein 0.02 Orthogroups_2024-Update
Glyma.14G223200 No alias OPC-8:0 CoA ligase1 0.03 Orthogroups_2024-Update
HORVU6Hr1G030390.2 No alias p-coumarate 0.03 Orthogroups_2024-Update
LOC_Os03g04000 No alias AMP-binding domain containing protein, expressed 0.03 Orthogroups_2024-Update
PSME_00015568-RA No alias (o24146|4cl2_tobac : 707.0) 4-coumarate--CoA ligase 2... 0.03 Orthogroups_2024-Update
PSME_00015569-RA No alias (o24146|4cl2_tobac : 689.0) 4-coumarate--CoA ligase 2... 0.03 Orthogroups_2024-Update
Seita.4G191500.1 No alias p-coumarate 0.02 Orthogroups_2024-Update
Seita.6G093400.1 No alias p-coumarate 0.02 Orthogroups_2024-Update
Seita.6G167900.1 No alias p-coumarate 0.03 Orthogroups_2024-Update
Sobic.004G272700.1 No alias p-coumarate 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0001671 ATPase activator activity IEP Predicted GO
MF GO:0003684 damaged DNA binding IEP Predicted GO
MF GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity IEP Predicted GO
MF GO:0003883 CTP synthase activity IEP Predicted GO
MF GO:0004556 alpha-amylase activity IEP Predicted GO
MF GO:0004664 prephenate dehydratase activity IEP Predicted GO
MF GO:0005509 calcium ion binding IEP Predicted GO
BP GO:0006220 pyrimidine nucleotide metabolic process IEP Predicted GO
BP GO:0006221 pyrimidine nucleotide biosynthetic process IEP Predicted GO
BP GO:0006289 nucleotide-excision repair IEP Predicted GO
BP GO:0006520 cellular amino acid metabolic process IEP Predicted GO
BP GO:0006558 L-phenylalanine metabolic process IEP Predicted GO
BP GO:0008652 cellular amino acid biosynthetic process IEP Predicted GO
BP GO:0009072 aromatic amino acid family metabolic process IEP Predicted GO
BP GO:0009073 aromatic amino acid family biosynthetic process IEP Predicted GO
BP GO:0009094 L-phenylalanine biosynthetic process IEP Predicted GO
BP GO:0009095 aromatic amino acid family biosynthetic process, prephenate pathway IEP Predicted GO
BP GO:0010498 proteasomal protein catabolic process IEP Predicted GO
MF GO:0016160 amylase activity IEP Predicted GO
BP GO:0016192 vesicle-mediated transport IEP Predicted GO
BP GO:0016458 gene silencing IEP Predicted GO
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
CC GO:0030118 clathrin coat IEP Predicted GO
CC GO:0030120 vesicle coat IEP Predicted GO
CC GO:0030125 clathrin vesicle coat IEP Predicted GO
CC GO:0030130 clathrin coat of trans-Golgi network vesicle IEP Predicted GO
CC GO:0030132 clathrin coat of coated pit IEP Predicted GO
BP GO:0030163 protein catabolic process IEP Predicted GO
MF GO:0030976 thiamine pyrophosphate binding IEP Predicted GO
BP GO:0031047 gene silencing by RNA IEP Predicted GO
BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEP Predicted GO
MF GO:0043565 sequence-specific DNA binding IEP Predicted GO
CC GO:0044431 Golgi apparatus part IEP Predicted GO
CC GO:0044433 cytoplasmic vesicle part IEP Predicted GO
MF GO:0051087 chaperone binding IEP Predicted GO
MF GO:0051287 NAD binding IEP Predicted GO
MF GO:0060590 ATPase regulator activity IEP Predicted GO
BP GO:0072527 pyrimidine-containing compound metabolic process IEP Predicted GO
BP GO:0072528 pyrimidine-containing compound biosynthetic process IEP Predicted GO
CC GO:0098797 plasma membrane protein complex IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
MF GO:1901681 sulfur compound binding IEP Predicted GO
BP GO:1902221 erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process IEP Predicted GO
BP GO:1902223 erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR025110 AMP-bd_C 451 486
IPR000873 AMP-dep_Synth/Lig 33 442
No external refs found!