Description : (at5g22220 : 366.0) Member of the E2F transcription factors, (cell cycle genes), key components of the cyclin D/retinoblastoma/E2F pathway. Binds DPA and RBR1 proteins. Expressed throughout the cell cycle. Abundance increased by auxin through stabilization of the protein. Elevates CDK levels and activity, even under hormone-free conditions. Promotes cell division and shortens cell doubling time, inhibits cell growth. Transgenic plants overexpressing AtE2Fa contained an increased level of AtE2Fb transcripts that is paralleled by an increase in the amount of the AtE2Fb protein, suggesting that AtE2Fb expression might actually be up-regulated by the AtE2Fa transcription factor.; E2F transcription factor 1 (E2F1); CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Transcription factor E2F/dimerisation partner (TDP) (InterPro:IPR003316), E2F Family (InterPro:IPR015633); BEST Arabidopsis thaliana protein match is: E2F transcription factor 3 (TAIR:AT2G36010.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 732.0) & (original description: no original description)
Gene families : OG_42_0001318 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001318_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_66734g0010 | |
Cluster | HCCA clusters: Cluster_148 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Brara.C01810.1 | No alias | component *(E2F) of DREAM cell cycle regulatory complex... | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003700 | DNA-binding transcription factor activity | IEA | InterProScan predictions |
CC | GO:0005667 | transcription factor complex | IEA | InterProScan predictions |
BP | GO:0006355 | regulation of transcription, DNA-templated | IEA | InterProScan predictions |
MF | GO:0046983 | protein dimerization activity | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0000160 | phosphorelay signal transduction system | IEP | Predicted GO |
MF | GO:0000166 | nucleotide binding | IEP | Predicted GO |
MF | GO:0001882 | nucleoside binding | IEP | Predicted GO |
MF | GO:0001883 | purine nucleoside binding | IEP | Predicted GO |
MF | GO:0003735 | structural constituent of ribosome | IEP | Predicted GO |
MF | GO:0005096 | GTPase activator activity | IEP | Predicted GO |
MF | GO:0005198 | structural molecule activity | IEP | Predicted GO |
MF | GO:0005525 | GTP binding | IEP | Predicted GO |
CC | GO:0005622 | intracellular | IEP | Predicted GO |
CC | GO:0005759 | mitochondrial matrix | IEP | Predicted GO |
CC | GO:0005840 | ribosome | IEP | Predicted GO |
CC | GO:0005956 | protein kinase CK2 complex | IEP | Predicted GO |
BP | GO:0006412 | translation | IEP | Predicted GO |
BP | GO:0006518 | peptide metabolic process | IEP | Predicted GO |
MF | GO:0008047 | enzyme activator activity | IEP | Predicted GO |
MF | GO:0017076 | purine nucleotide binding | IEP | Predicted GO |
MF | GO:0017111 | nucleoside-triphosphatase activity | IEP | Predicted GO |
MF | GO:0019001 | guanyl nucleotide binding | IEP | Predicted GO |
MF | GO:0019207 | kinase regulator activity | IEP | Predicted GO |
MF | GO:0019887 | protein kinase regulator activity | IEP | Predicted GO |
MF | GO:0030234 | enzyme regulator activity | IEP | Predicted GO |
CC | GO:0031974 | membrane-enclosed lumen | IEP | Predicted GO |
MF | GO:0032549 | ribonucleoside binding | IEP | Predicted GO |
MF | GO:0032550 | purine ribonucleoside binding | IEP | Predicted GO |
MF | GO:0032553 | ribonucleotide binding | IEP | Predicted GO |
MF | GO:0032555 | purine ribonucleotide binding | IEP | Predicted GO |
MF | GO:0032561 | guanyl ribonucleotide binding | IEP | Predicted GO |
MF | GO:0035091 | phosphatidylinositol binding | IEP | Predicted GO |
BP | GO:0035556 | intracellular signal transduction | IEP | Predicted GO |
MF | GO:0035639 | purine ribonucleoside triphosphate binding | IEP | Predicted GO |
BP | GO:0043043 | peptide biosynthetic process | IEP | Predicted GO |
MF | GO:0043168 | anion binding | IEP | Predicted GO |
CC | GO:0043226 | organelle | IEP | Predicted GO |
CC | GO:0043228 | non-membrane-bounded organelle | IEP | Predicted GO |
CC | GO:0043229 | intracellular organelle | IEP | Predicted GO |
CC | GO:0043232 | intracellular non-membrane-bounded organelle | IEP | Predicted GO |
CC | GO:0043233 | organelle lumen | IEP | Predicted GO |
BP | GO:0043603 | cellular amide metabolic process | IEP | Predicted GO |
BP | GO:0043604 | amide biosynthetic process | IEP | Predicted GO |
CC | GO:0044444 | cytoplasmic part | IEP | Predicted GO |
CC | GO:0070013 | intracellular organelle lumen | IEP | Predicted GO |
MF | GO:0097367 | carbohydrate derivative binding | IEP | Predicted GO |
MF | GO:1901265 | nucleoside phosphate binding | IEP | Predicted GO |
CC | GO:1990904 | ribonucleoprotein complex | IEP | Predicted GO |
No external refs found! |