MA_66734g0010


Description : (at5g22220 : 366.0) Member of the E2F transcription factors, (cell cycle genes), key components of the cyclin D/retinoblastoma/E2F pathway. Binds DPA and RBR1 proteins. Expressed throughout the cell cycle. Abundance increased by auxin through stabilization of the protein. Elevates CDK levels and activity, even under hormone-free conditions. Promotes cell division and shortens cell doubling time, inhibits cell growth. Transgenic plants overexpressing AtE2Fa contained an increased level of AtE2Fb transcripts that is paralleled by an increase in the amount of the AtE2Fb protein, suggesting that AtE2Fb expression might actually be up-regulated by the AtE2Fa transcription factor.; E2F transcription factor 1 (E2F1); CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Transcription factor E2F/dimerisation partner (TDP) (InterPro:IPR003316), E2F Family (InterPro:IPR015633); BEST Arabidopsis thaliana protein match is: E2F transcription factor 3 (TAIR:AT2G36010.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 732.0) & (original description: no original description)


Gene families : OG_42_0001318 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001318_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_66734g0010
Cluster HCCA clusters: Cluster_148

Target Alias Description ECC score Gene Family Method Actions
Brara.C01810.1 No alias component *(E2F) of DREAM cell cycle regulatory complex... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003700 DNA-binding transcription factor activity IEA InterProScan predictions
CC GO:0005667 transcription factor complex IEA InterProScan predictions
BP GO:0006355 regulation of transcription, DNA-templated IEA InterProScan predictions
MF GO:0046983 protein dimerization activity IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0000160 phosphorelay signal transduction system IEP Predicted GO
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0001882 nucleoside binding IEP Predicted GO
MF GO:0001883 purine nucleoside binding IEP Predicted GO
MF GO:0003735 structural constituent of ribosome IEP Predicted GO
MF GO:0005096 GTPase activator activity IEP Predicted GO
MF GO:0005198 structural molecule activity IEP Predicted GO
MF GO:0005525 GTP binding IEP Predicted GO
CC GO:0005622 intracellular IEP Predicted GO
CC GO:0005759 mitochondrial matrix IEP Predicted GO
CC GO:0005840 ribosome IEP Predicted GO
CC GO:0005956 protein kinase CK2 complex IEP Predicted GO
BP GO:0006412 translation IEP Predicted GO
BP GO:0006518 peptide metabolic process IEP Predicted GO
MF GO:0008047 enzyme activator activity IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0017111 nucleoside-triphosphatase activity IEP Predicted GO
MF GO:0019001 guanyl nucleotide binding IEP Predicted GO
MF GO:0019207 kinase regulator activity IEP Predicted GO
MF GO:0019887 protein kinase regulator activity IEP Predicted GO
MF GO:0030234 enzyme regulator activity IEP Predicted GO
CC GO:0031974 membrane-enclosed lumen IEP Predicted GO
MF GO:0032549 ribonucleoside binding IEP Predicted GO
MF GO:0032550 purine ribonucleoside binding IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032561 guanyl ribonucleotide binding IEP Predicted GO
MF GO:0035091 phosphatidylinositol binding IEP Predicted GO
BP GO:0035556 intracellular signal transduction IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
BP GO:0043043 peptide biosynthetic process IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
CC GO:0043226 organelle IEP Predicted GO
CC GO:0043228 non-membrane-bounded organelle IEP Predicted GO
CC GO:0043229 intracellular organelle IEP Predicted GO
CC GO:0043232 intracellular non-membrane-bounded organelle IEP Predicted GO
CC GO:0043233 organelle lumen IEP Predicted GO
BP GO:0043603 cellular amide metabolic process IEP Predicted GO
BP GO:0043604 amide biosynthetic process IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
CC GO:0070013 intracellular organelle lumen IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
CC GO:1990904 ribonucleoprotein complex IEP Predicted GO
InterPro domains Description Start Stop
IPR032198 E2F_CC-MB 156 255
IPR003316 E2F_WHTH_DNA-bd_dom 77 140
No external refs found!