MA_70509g0010


Description : (o24146|4cl2_tobac : 763.0) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2) (4-coumaroyl-CoA synthase 2) - Nicotiana tabacum (Common tobacco) & (at1g51680 : 718.0) encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. In addition to 4-coumarate, it also converts ferulate. The catalytic efficiency was in the following (descending) order: p-coumaric acid, ferulic acid, caffeic acid and 5-OH-ferulic acid. At4CL1 was unable to use sinapic acid as substrate.; 4-coumarate:CoA ligase 1 (4CL1); CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: 4-coumarate:CoA ligase 2 (TAIR:AT3G21240.1); Has 83069 Blast hits to 75791 proteins in 3772 species: Archae - 1181; Bacteria - 53827; Metazoa - 3457; Fungi - 4480; Plants - 2791; Viruses - 1; Other Eukaryotes - 17332 (source: NCBI BLink). & (reliability: 1436.0) & (original description: no original description)


Gene families : OG_42_0000133 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000133_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_70509g0010
Cluster HCCA clusters: Cluster_66

Target Alias Description ECC score Gene Family Method Actions
143817 No alias OPC-8:0 CoA ligase1 0.03 Orthogroups_2024-Update
A4A49_10638 No alias 4-coumarate--coa ligase 2 0.03 Orthogroups_2024-Update
A4A49_15235 No alias 4-coumarate--coa ligase 2 0.05 Orthogroups_2024-Update
Bradi3g37300 No alias 4-coumarate:CoA ligase 2 0.02 Orthogroups_2024-Update
Bradi3g52350 No alias 4-coumarate:CoA ligase 3 0.04 Orthogroups_2024-Update
Bradi5g04760 No alias acyl-CoA synthetase 5 0.03 Orthogroups_2024-Update
Brara.G01099.1 No alias OPC-8 0.03 Orthogroups_2024-Update
GRMZM2G122787 No alias AMP-dependent synthetase and ligase family protein 0.03 Orthogroups_2024-Update
Glyma.10G197900 No alias OPC-8:0 CoA ligase1 0.04 Orthogroups_2024-Update
Glyma.11G010500 No alias 4-coumarate:CoA ligase 3 0.04 Orthogroups_2024-Update
Glyma.15G001700 No alias 4-coumarate:CoA ligase 2 0.03 Orthogroups_2024-Update
Glyma.18G076900 No alias acyl-CoA synthetase 5 0.03 Orthogroups_2024-Update
Glyma.19G075800 No alias AMP-dependent synthetase and ligase family protein 0.02 Orthogroups_2024-Update
LOC_Os03g04000 No alias AMP-binding domain containing protein, expressed 0.03 Orthogroups_2024-Update
LOC_Os06g44620 No alias AMP-binding domain containing protein, expressed 0.03 Orthogroups_2024-Update
MA_10426784g0020 No alias (at4g05160 : 437.0) Encodes a peroxisomal protein... 0.04 Orthogroups_2024-Update
MA_10432138g0010 No alias (at1g20510 : 477.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.04 Orthogroups_2024-Update
MA_4881g0010 No alias (at1g20510 : 253.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.04 Orthogroups_2024-Update
Mp5g01200.1 No alias p-coumarate:CoA ligase. 4-coumarate:CoA ligase (4CL) 0.03 Orthogroups_2024-Update
PSME_00010613-RA No alias (at1g20510 : 572.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.03 Orthogroups_2024-Update
PSME_00013809-RA No alias (at1g20510 : 678.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.04 Orthogroups_2024-Update
PSME_00017730-RA No alias (at1g20510 : 538.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.05 Orthogroups_2024-Update
PSME_00041965-RA No alias (at1g20510 : 583.0) OPC-8:0 CoA ligase1 (OPCL1);... 0.03 Orthogroups_2024-Update
Potri.003G188500 No alias 4-coumarate:CoA ligase 2 0.03 Orthogroups_2024-Update
Potri.005G248500 No alias OPC-8:0 CoA ligase1 0.03 Orthogroups_2024-Update
Potri.010G057000 No alias AMP-dependent synthetase and ligase family protein 0.05 Orthogroups_2024-Update
Potri.012G094800 No alias AMP-dependent synthetase and ligase family protein 0.03 Orthogroups_2024-Update
Potri.012G095000 No alias AMP-dependent synthetase and ligase family protein 0.03 Orthogroups_2024-Update
Pp1s20_346V6 No alias 4-coumarate: ligase 0.02 Orthogroups_2024-Update
Pp1s71_170V6 No alias 4-coumarate: ligase 0.03 Orthogroups_2024-Update
Pp1s96_224V6 No alias 4-coumarate:coenzyme a ligase 2 0.03 Orthogroups_2024-Update
Seita.1G065800.1 No alias p-coumarate 0.04 Orthogroups_2024-Update
Seita.4G191500.1 No alias p-coumarate 0.03 Orthogroups_2024-Update
Seita.6G167900.1 No alias p-coumarate 0.04 Orthogroups_2024-Update
Seita.9G552000.1 No alias OPC-8 0.03 Orthogroups_2024-Update
Sobic.004G062500.1 No alias p-coumarate 0.04 Orthogroups_2024-Update
Sobic.007G089900.1 No alias p-coumarate 0.04 Orthogroups_2024-Update
Solyc03g097030 No alias 4-coumarate--CoA ligase 0.03 Orthogroups_2024-Update
Solyc03g117870 No alias 4-coumarate--CoA ligase 0.03 Orthogroups_2024-Update
Sopen03g036780 No alias AMP-binding enzyme 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0000155 phosphorelay sensor kinase activity IEP Predicted GO
MF GO:0004672 protein kinase activity IEP Predicted GO
MF GO:0004673 protein histidine kinase activity IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
MF GO:0008289 lipid binding IEP Predicted GO
MF GO:0016301 kinase activity IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016740 transferase activity IEP Predicted GO
MF GO:0016757 transferase activity, transferring glycosyl groups IEP Predicted GO
MF GO:0016758 transferase activity, transferring hexosyl groups IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
MF GO:0016775 phosphotransferase activity, nitrogenous group as acceptor IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
InterPro domains Description Start Stop
IPR000873 AMP-dep_Synth/Lig 46 456
IPR025110 AMP-bd_C 465 541
No external refs found!