Description : (o24146|4cl2_tobac : 763.0) 4-coumarate--CoA ligase 2 (EC 6.2.1.12) (4CL 2) (4-coumaroyl-CoA synthase 2) - Nicotiana tabacum (Common tobacco) & (at1g51680 : 718.0) encodes an isoform of 4-coumarate:CoA ligase (4CL), which is involved in the last step of the general phenylpropanoid pathway. In addition to 4-coumarate, it also converts ferulate. The catalytic efficiency was in the following (descending) order: p-coumaric acid, ferulic acid, caffeic acid and 5-OH-ferulic acid. At4CL1 was unable to use sinapic acid as substrate.; 4-coumarate:CoA ligase 1 (4CL1); CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: 4-coumarate:CoA ligase 2 (TAIR:AT3G21240.1); Has 83069 Blast hits to 75791 proteins in 3772 species: Archae - 1181; Bacteria - 53827; Metazoa - 3457; Fungi - 4480; Plants - 2791; Viruses - 1; Other Eukaryotes - 17332 (source: NCBI BLink). & (reliability: 1436.0) & (original description: no original description)
Gene families : OG_42_0000133 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000133_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_70509g0010 | |
Cluster | HCCA clusters: Cluster_66 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
143817 | No alias | OPC-8:0 CoA ligase1 | 0.03 | Orthogroups_2024-Update | |
A4A49_10638 | No alias | 4-coumarate--coa ligase 2 | 0.03 | Orthogroups_2024-Update | |
A4A49_15235 | No alias | 4-coumarate--coa ligase 2 | 0.05 | Orthogroups_2024-Update | |
Bradi3g37300 | No alias | 4-coumarate:CoA ligase 2 | 0.02 | Orthogroups_2024-Update | |
Bradi3g52350 | No alias | 4-coumarate:CoA ligase 3 | 0.04 | Orthogroups_2024-Update | |
Bradi5g04760 | No alias | acyl-CoA synthetase 5 | 0.03 | Orthogroups_2024-Update | |
Brara.G01099.1 | No alias | OPC-8 | 0.03 | Orthogroups_2024-Update | |
GRMZM2G122787 | No alias | AMP-dependent synthetase and ligase family protein | 0.03 | Orthogroups_2024-Update | |
Glyma.10G197900 | No alias | OPC-8:0 CoA ligase1 | 0.04 | Orthogroups_2024-Update | |
Glyma.11G010500 | No alias | 4-coumarate:CoA ligase 3 | 0.04 | Orthogroups_2024-Update | |
Glyma.15G001700 | No alias | 4-coumarate:CoA ligase 2 | 0.03 | Orthogroups_2024-Update | |
Glyma.18G076900 | No alias | acyl-CoA synthetase 5 | 0.03 | Orthogroups_2024-Update | |
Glyma.19G075800 | No alias | AMP-dependent synthetase and ligase family protein | 0.02 | Orthogroups_2024-Update | |
LOC_Os03g04000 | No alias | AMP-binding domain containing protein, expressed | 0.03 | Orthogroups_2024-Update | |
LOC_Os06g44620 | No alias | AMP-binding domain containing protein, expressed | 0.03 | Orthogroups_2024-Update | |
MA_10426784g0020 | No alias | (at4g05160 : 437.0) Encodes a peroxisomal protein... | 0.04 | Orthogroups_2024-Update | |
MA_10432138g0010 | No alias | (at1g20510 : 477.0) OPC-8:0 CoA ligase1 (OPCL1);... | 0.04 | Orthogroups_2024-Update | |
MA_4881g0010 | No alias | (at1g20510 : 253.0) OPC-8:0 CoA ligase1 (OPCL1);... | 0.04 | Orthogroups_2024-Update | |
Mp5g01200.1 | No alias | p-coumarate:CoA ligase. 4-coumarate:CoA ligase (4CL) | 0.03 | Orthogroups_2024-Update | |
PSME_00010613-RA | No alias | (at1g20510 : 572.0) OPC-8:0 CoA ligase1 (OPCL1);... | 0.03 | Orthogroups_2024-Update | |
PSME_00013809-RA | No alias | (at1g20510 : 678.0) OPC-8:0 CoA ligase1 (OPCL1);... | 0.04 | Orthogroups_2024-Update | |
PSME_00017730-RA | No alias | (at1g20510 : 538.0) OPC-8:0 CoA ligase1 (OPCL1);... | 0.05 | Orthogroups_2024-Update | |
PSME_00041965-RA | No alias | (at1g20510 : 583.0) OPC-8:0 CoA ligase1 (OPCL1);... | 0.03 | Orthogroups_2024-Update | |
Potri.003G188500 | No alias | 4-coumarate:CoA ligase 2 | 0.03 | Orthogroups_2024-Update | |
Potri.005G248500 | No alias | OPC-8:0 CoA ligase1 | 0.03 | Orthogroups_2024-Update | |
Potri.010G057000 | No alias | AMP-dependent synthetase and ligase family protein | 0.05 | Orthogroups_2024-Update | |
Potri.012G094800 | No alias | AMP-dependent synthetase and ligase family protein | 0.03 | Orthogroups_2024-Update | |
Potri.012G095000 | No alias | AMP-dependent synthetase and ligase family protein | 0.03 | Orthogroups_2024-Update | |
Pp1s20_346V6 | No alias | 4-coumarate: ligase | 0.02 | Orthogroups_2024-Update | |
Pp1s71_170V6 | No alias | 4-coumarate: ligase | 0.03 | Orthogroups_2024-Update | |
Pp1s96_224V6 | No alias | 4-coumarate:coenzyme a ligase 2 | 0.03 | Orthogroups_2024-Update | |
Seita.1G065800.1 | No alias | p-coumarate | 0.04 | Orthogroups_2024-Update | |
Seita.4G191500.1 | No alias | p-coumarate | 0.03 | Orthogroups_2024-Update | |
Seita.6G167900.1 | No alias | p-coumarate | 0.04 | Orthogroups_2024-Update | |
Seita.9G552000.1 | No alias | OPC-8 | 0.03 | Orthogroups_2024-Update | |
Sobic.004G062500.1 | No alias | p-coumarate | 0.04 | Orthogroups_2024-Update | |
Sobic.007G089900.1 | No alias | p-coumarate | 0.04 | Orthogroups_2024-Update | |
Solyc03g097030 | No alias | 4-coumarate--CoA ligase | 0.03 | Orthogroups_2024-Update | |
Solyc03g117870 | No alias | 4-coumarate--CoA ligase | 0.03 | Orthogroups_2024-Update | |
Sopen03g036780 | No alias | AMP-binding enzyme | 0.03 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003824 | catalytic activity | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0000155 | phosphorelay sensor kinase activity | IEP | Predicted GO |
MF | GO:0004672 | protein kinase activity | IEP | Predicted GO |
MF | GO:0004673 | protein histidine kinase activity | IEP | Predicted GO |
BP | GO:0006464 | cellular protein modification process | IEP | Predicted GO |
BP | GO:0006468 | protein phosphorylation | IEP | Predicted GO |
BP | GO:0006793 | phosphorus metabolic process | IEP | Predicted GO |
BP | GO:0006796 | phosphate-containing compound metabolic process | IEP | Predicted GO |
MF | GO:0008289 | lipid binding | IEP | Predicted GO |
MF | GO:0016301 | kinase activity | IEP | Predicted GO |
BP | GO:0016310 | phosphorylation | IEP | Predicted GO |
MF | GO:0016740 | transferase activity | IEP | Predicted GO |
MF | GO:0016757 | transferase activity, transferring glycosyl groups | IEP | Predicted GO |
MF | GO:0016758 | transferase activity, transferring hexosyl groups | IEP | Predicted GO |
MF | GO:0016772 | transferase activity, transferring phosphorus-containing groups | IEP | Predicted GO |
MF | GO:0016773 | phosphotransferase activity, alcohol group as acceptor | IEP | Predicted GO |
MF | GO:0016775 | phosphotransferase activity, nitrogenous group as acceptor | IEP | Predicted GO |
BP | GO:0036211 | protein modification process | IEP | Predicted GO |
BP | GO:0043412 | macromolecule modification | IEP | Predicted GO |
BP | GO:0044260 | cellular macromolecule metabolic process | IEP | Predicted GO |
BP | GO:0044267 | cellular protein metabolic process | IEP | Predicted GO |
MF | GO:0140096 | catalytic activity, acting on a protein | IEP | Predicted GO |
No external refs found! |