Description : (p28002|comt1_medsa : 127.0) Caffeic acid 3-O-methyltransferase (EC 2.1.1.68) (S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase) (COMT) (CAOMT) - Medicago sativa (Alfalfa) & (at5g54160 : 112.0) A caffeic acid/5-hydroxyferulic acid O-methyltransferase. Interacts with 14-4-3 proteins in yeast 2 hybrid assay. AtOMT1 (At5g54160) encodes a flavonol 3Ã-O-methyltransferase that is highly active towards quercetin and myricetin. The substrate specificity identifies the enzyme as flavonol 3Ã-methyltransferase which replaces the former annotation of the gene to encode a caffeic acid/5-hydroxyferulic acid O-methyltransferase; O-methyltransferase 1 (OMT1); FUNCTIONS IN: myricetin 3'-O-methyltransferase activity, quercetin 3-O-methyltransferase activity, caffeate O-methyltransferase activity; INVOLVED IN: lignin biosynthetic process, flavonol biosynthetic process; LOCATED IN: cytosol, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase family protein (TAIR:AT1G77520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 204.0) & (original description: no original description)
Gene families : OG_42_0000016 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000016_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_749919g0010 | |
Cluster | HCCA clusters: Cluster_66 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
At5g54160 | No alias | Flavone 3'-O-methyltransferase 1... | 0.02 | Orthogroups_2024-Update | |
Bradi3g16530 | No alias | O-methyltransferase 1 | 0.03 | Orthogroups_2024-Update | |
Brara.F03756.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
Brara.G02144.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
GRMZM2G140996 | No alias | O-methyltransferase family protein | 0.02 | Orthogroups_2024-Update | |
Glyma.18G263700 | No alias | O-methyltransferase 1 | 0.03 | Orthogroups_2024-Update | |
HORVU1Hr1G076660.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
HORVU4Hr1G076050.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
Kfl00158_0170 | kfl00158_0170_v1.... | (at5g54160 : 162.0) A caffeic acid/5-hydroxyferulic acid... | 0.02 | Orthogroups_2024-Update | |
MA_1665780g0010 | No alias | no hits & (original description: no original description) | 0.04 | Orthogroups_2024-Update | |
MA_363801g0010 | No alias | (q8w013|comt1_catro : 228.0) Caffeic acid... | 0.05 | Orthogroups_2024-Update | |
MA_76956g0010 | No alias | (q9fqy8|comt1_capan : 399.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
PSME_00006680-RA | No alias | (q9fqy8|comt1_capan : 424.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
PSME_00021108-RA | No alias | (p28002|comt1_medsa : 130.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
PSME_00022848-RA | No alias | no hits & (original description: no original description) | 0.05 | Orthogroups_2024-Update | |
PSME_00053129-RA | No alias | (q8w013|comt1_catro : 265.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
Potri.012G006400 | No alias | O-methyltransferase 1 | 0.02 | Orthogroups_2024-Update | |
Potri.013G136400 | No alias | O-methyltransferase family protein | 0.03 | Orthogroups_2024-Update | |
Potri.014G106600 | No alias | O-methyltransferase 1 | 0.02 | Orthogroups_2024-Update | |
Sobic.001G354400.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.04 | Orthogroups_2024-Update | |
Sobic.005G224400.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.04 | Orthogroups_2024-Update | |
Sobic.009G197800.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
Sobic.010G230800.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
Sobic.010G231000.2 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
Sobic.010G234400.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
Solyc01g068550 | No alias | No description available | 0.02 | Orthogroups_2024-Update | |
Sopen06g022970 | No alias | O-methyltransferase | 0.03 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0008171 | O-methyltransferase activity | IEA | InterProScan predictions |
MF | GO:0046983 | protein dimerization activity | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005506 | iron ion binding | IEP | Predicted GO |
BP | GO:0006950 | response to stress | IEP | Predicted GO |
BP | GO:0006952 | defense response | IEP | Predicted GO |
MF | GO:0016651 | oxidoreductase activity, acting on NAD(P)H | IEP | Predicted GO |
MF | GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | IEP | Predicted GO |
MF | GO:0016887 | ATPase activity | IEP | Predicted GO |
MF | GO:0020037 | heme binding | IEP | Predicted GO |
MF | GO:0046906 | tetrapyrrole binding | IEP | Predicted GO |
MF | GO:0050664 | oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor | IEP | Predicted GO |
No external refs found! |