MA_8055948g0010

Description : (at1g64660 : 551.0) Encodes a functional methionine gamma-lyase, a cytosolic enzyme catalyzes the degradation of methionine into methanethiol, alpha-ketobutyrate and ammonia. The catabolism of excess methionine is important to methionine homeostasis.; methionine gamma-lyase (MGL); CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (InterPro:IPR000277), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein (TAIR:AT3G01120.1); Has 19547 Blast hits to 19544 proteins in 2474 species: Archae - 216; Bacteria - 11847; Metazoa - 211; Fungi - 771; Plants - 270; Viruses - 0; Other Eukaryotes - 6232 (source: NCBI BLink). & (reliability: 1102.0) & (original description: no original description)

Gene families : OG_42_0003211 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003211_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Picea release: MA_8055948g0010
Cluster	HCCA clusters: Cluster_14

Target	Alias	Description	ECC score	Gene Family Method
A4A49_38037	No alias	methionine gamma-lyase	0.02	Orthogroups_2024-Update
MA_80729g0010	No alias	(at1g64660 : 140.0) Encodes a functional methionine...	0.03	Orthogroups_2024-Update
Potri.003G187032	No alias	methionine gamma-lyase	0.03	Orthogroups_2024-Update
Potri.003G187100	No alias	methionine gamma-lyase	0.03	Orthogroups_2024-Update
Pp1s25_78V6	No alias	cystathionine gamma-synthase	0.04	Orthogroups_2024-Update
Seita.9G191400.1	No alias	methionine gamma-lyase & methionine gamma-lyase & EC_4.4...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0008144	drug binding	None	Extended
MF	GO:0019842	vitamin binding	None	Extended
MF	GO:0030170	pyridoxal phosphate binding	IEA	InterProScan predictions
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050662	coenzyme binding	None	Extended
MF	GO:0070279	vitamin B6 binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0004420	hydroxymethylglutaryl-CoA reductase (NADPH) activity	IEP	Predicted GO
MF	GO:0004866	endopeptidase inhibitor activity	IEP	Predicted GO
MF	GO:0004867	serine-type endopeptidase inhibitor activity	IEP	Predicted GO
BP	GO:0006950	response to stress	IEP	Predicted GO
BP	GO:0006952	defense response	IEP	Predicted GO
BP	GO:0006979	response to oxidative stress	IEP	Predicted GO
MF	GO:0008168	methyltransferase activity	IEP	Predicted GO
BP	GO:0015936	coenzyme A metabolic process	IEP	Predicted GO
MF	GO:0030414	peptidase inhibitor activity	IEP	Predicted GO
BP	GO:0033865	nucleoside bisphosphate metabolic process	IEP	Predicted GO
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	IEP	Predicted GO
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	IEP	Predicted GO
BP	GO:0050896	response to stimulus	IEP	Predicted GO
MF	GO:0061134	peptidase regulator activity	IEP	Predicted GO
MF	GO:0061135	endopeptidase regulator activity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000277	Cys/Met-Metab_PyrdxlP-dep_enz	45	381

External Links

No external refs found!

MA_8055948g0010

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation