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Description : (q8w013|comt1_catro : 181.0) Caffeic acid 3-O-methyltransferase (EC 2.1.1.68) (S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase) (COMT) (CAOMT) - Catharanthus roseus (Rosy periwinkle) (Madagascar periwinkle) & (at5g54160 : 174.0) A caffeic acid/5-hydroxyferulic acid O-methyltransferase. Interacts with 14-4-3 proteins in yeast 2 hybrid assay. AtOMT1 (At5g54160) encodes a flavonol 3Ã-O-methyltransferase that is highly active towards quercetin and myricetin. The substrate specificity identifies the enzyme as flavonol 3Ã-methyltransferase which replaces the former annotation of the gene to encode a caffeic acid/5-hydroxyferulic acid O-methyltransferase; O-methyltransferase 1 (OMT1); FUNCTIONS IN: myricetin 3'-O-methyltransferase activity, quercetin 3-O-methyltransferase activity, caffeate O-methyltransferase activity; INVOLVED IN: lignin biosynthetic process, flavonol biosynthetic process; LOCATED IN: cytosol, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase family protein (TAIR:AT1G77520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 336.0) & (original description: no original description)
Gene families : OG_42_0000016 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000016_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
| Type | Description | Actions |
|---|---|---|
| Neighborhood | Picea release: MA_84582g0010 | |
| Cluster | HCCA clusters: Cluster_262 |
| Target | Alias | Description | ECC score | Gene Family Method | Actions |
|---|---|---|---|---|---|
| A4A49_41648 | No alias | trans-resveratrol di-o-methyltransferase | 0.02 | Orthogroups_2024-Update | |
| At1g21110 | No alias | Indole glucosinolate O-methyltransferase 3... | 0.03 | Orthogroups_2024-Update | |
| Bradi2g39511 | No alias | O-methyltransferase family protein | 0.02 | Orthogroups_2024-Update | |
| Bradi3g16530 | No alias | O-methyltransferase 1 | 0.04 | Orthogroups_2024-Update | |
| Bradi4g18065 | No alias | O-methyltransferase family protein | 0.03 | Orthogroups_2024-Update | |
| Brara.F03756.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
| Brara.G02172.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
| GRMZM2G100754 | No alias | O-methyltransferase family protein | 0.03 | Orthogroups_2024-Update | |
| Glyma.08G248000 | No alias | O-methyltransferase family protein | 0.03 | Orthogroups_2024-Update | |
| Glyma.09G094600 | No alias | O-methyltransferase family protein | 0.03 | Orthogroups_2024-Update | |
| Glyma.09G281900 | No alias | O-methyltransferase 1 | 0.04 | Orthogroups_2024-Update | |
| Glyma.10G176600 | No alias | O-methyltransferase family protein | 0.02 | Orthogroups_2024-Update | |
| Glyma.12G109800 | No alias | O-methyltransferase 1 | 0.02 | Orthogroups_2024-Update | |
| HORVU4Hr1G012540.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| MA_1665780g0010 | No alias | no hits & (original description: no original description) | 0.04 | Orthogroups_2024-Update | |
| MA_5226589g0010 | No alias | no hits & (original description: no original description) | 0.03 | Orthogroups_2024-Update | |
| MA_74925g0020 | No alias | no hits & (original description: no original description) | 0.03 | Orthogroups_2024-Update | |
| MA_86945g0010 | No alias | (at5g54160 : 94.7) A caffeic acid/5-hydroxyferulic acid... | 0.04 | Orthogroups_2024-Update | |
| PSME_00002255-RA | No alias | (q9fqy8|comt1_capan : 423.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
| PSME_00045308-RA | No alias | (p28002|comt1_medsa : 243.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
| PSME_00051686-RA | No alias | (p28002|comt1_medsa : 274.0) Caffeic acid... | 0.02 | Orthogroups_2024-Update | |
| PSME_00052626-RA | No alias | (p28002|comt1_medsa : 204.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
| Potri.001G451100 | No alias | O-methyltransferase 1 | 0.03 | Orthogroups_2024-Update | |
| Potri.004G050500 | No alias | O-methyltransferase family protein | 0.03 | Orthogroups_2024-Update | |
| Potri.011G150500 | No alias | O-methyltransferase 1 | 0.03 | Orthogroups_2024-Update | |
| Potri.014G106600 | No alias | O-methyltransferase 1 | 0.03 | Orthogroups_2024-Update | |
| Seita.1G045400.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| Seita.9G382900.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.02 | Orthogroups_2024-Update | |
| Sobic.009G197600.4 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
| Solyc03g097700 | No alias | O-methyltransferase (AHRD V3.3 *** F6M2M1_VITPS) | 0.03 | Orthogroups_2024-Update | |
| Solyc10g008120 | No alias | O-methyltransferase (AHRD V3.3 *** A0A1B4Z3W3_9ROSA) | 0.02 | Orthogroups_2024-Update |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| MF | GO:0008171 | O-methyltransferase activity | IEA | InterProScan predictions |
| Type | GO Term | Name | Evidence | Source |
|---|---|---|---|---|
| BP | GO:0006810 | transport | IEP | Predicted GO |
| BP | GO:0006811 | ion transport | IEP | Predicted GO |
| BP | GO:0006812 | cation transport | IEP | Predicted GO |
| BP | GO:0006814 | sodium ion transport | IEP | Predicted GO |
| BP | GO:0008272 | sulfate transport | IEP | Predicted GO |
| MF | GO:0015075 | ion transmembrane transporter activity | IEP | Predicted GO |
| MF | GO:0015077 | monovalent inorganic cation transmembrane transporter activity | IEP | Predicted GO |
| MF | GO:0015078 | proton transmembrane transporter activity | IEP | Predicted GO |
| MF | GO:0015116 | sulfate transmembrane transporter activity | IEP | Predicted GO |
| MF | GO:0015318 | inorganic molecular entity transmembrane transporter activity | IEP | Predicted GO |
| BP | GO:0015672 | monovalent inorganic cation transport | IEP | Predicted GO |
| BP | GO:0015988 | energy coupled proton transmembrane transport, against electrochemical gradient | IEP | Predicted GO |
| BP | GO:0015991 | ATP hydrolysis coupled proton transport | IEP | Predicted GO |
| MF | GO:0022890 | inorganic cation transmembrane transporter activity | IEP | Predicted GO |
| CC | GO:0033177 | proton-transporting two-sector ATPase complex, proton-transporting domain | IEP | Predicted GO |
| BP | GO:0034220 | ion transmembrane transport | IEP | Predicted GO |
| BP | GO:0051179 | localization | IEP | Predicted GO |
| BP | GO:0051234 | establishment of localization | IEP | Predicted GO |
| BP | GO:0072348 | sulfur compound transport | IEP | Predicted GO |
| BP | GO:0090662 | ATP hydrolysis coupled transmembrane transport | IEP | Predicted GO |
| BP | GO:0098655 | cation transmembrane transport | IEP | Predicted GO |
| BP | GO:0098660 | inorganic ion transmembrane transport | IEP | Predicted GO |
| BP | GO:0098662 | inorganic cation transmembrane transport | IEP | Predicted GO |
| CC | GO:0098796 | membrane protein complex | IEP | Predicted GO |
| BP | GO:0099131 | ATP hydrolysis coupled ion transmembrane transport | IEP | Predicted GO |
| BP | GO:0099132 | ATP hydrolysis coupled cation transmembrane transport | IEP | Predicted GO |
| MF | GO:1901682 | sulfur compound transmembrane transporter activity | IEP | Predicted GO |
| BP | GO:1902600 | proton transmembrane transport | IEP | Predicted GO |
| InterPro domains | Description | Start | Stop |
|---|---|---|---|
| IPR001077 | O_MeTrfase_2 | 2 | 185 |
| No external refs found! |