Description : (at4g19710 : 212.0) Encodes a bifunctional aspartate kinase/homoserine dehydrogenase. These two activities catalyze the first and the third steps toward the synthesis of the essential amino acids threonine, isoleucine and methionine.; aspartate kinase-homoserine dehydrogenase ii (AK-HSDH II); FUNCTIONS IN: homoserine dehydrogenase activity, aspartate kinase activity; INVOLVED IN: aspartate family amino acid biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aspartate/glutamate/uridylate kinase (InterPro:IPR001048), Homoserine dehydrogenase, catalytic (InterPro:IPR001342), Amino acid-binding ACT (InterPro:IPR002912), Aspartate/homoserine dehydrogenase, NAD-binding (InterPro:IPR005106), Aspartate kinase, conserved site (InterPro:IPR018042), NAD(P)-binding domain (InterPro:IPR016040), Aspartate kinase domain (InterPro:IPR001341), Bifunctional aspartokinase/homoserine dehydrogenase I (InterPro:IPR011147), Homoserine dehydrogenase, conserved site (InterPro:IPR019811); BEST Arabidopsis thaliana protein match is: aspartate kinase-homoserine dehydrogenase i (TAIR:AT1G31230.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (p49079|akh1_maize : 203.0) Bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplast precursor (AK-HD 1) (AK-HSDH 1) [Includes: Aspartokinase (EC 2.7.2.4); Homoserine dehydrogenase (EC 1.1.1.3)] - Zea mays (Maize) & (reliability: 424.0) & (original description: no original description)
Gene families : OG_42_0120105 (Orthogroups_2024-Update) Phylogenetic Tree(s): No tree available for this family
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_850263g0010 | |
Cluster | HCCA clusters: Cluster_149 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0006520 | cellular amino acid metabolic process | IEA | InterProScan predictions |
BP | GO:0055114 | oxidation-reduction process | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003993 | acid phosphatase activity | IEP | Predicted GO |
MF | GO:0004611 | phosphoenolpyruvate carboxykinase activity | IEP | Predicted GO |
MF | GO:0004612 | phosphoenolpyruvate carboxykinase (ATP) activity | IEP | Predicted GO |
BP | GO:0005996 | monosaccharide metabolic process | IEP | Predicted GO |
BP | GO:0006006 | glucose metabolic process | IEP | Predicted GO |
BP | GO:0006094 | gluconeogenesis | IEP | Predicted GO |
MF | GO:0016791 | phosphatase activity | IEP | Predicted GO |
MF | GO:0016830 | carbon-carbon lyase activity | IEP | Predicted GO |
MF | GO:0016831 | carboxy-lyase activity | IEP | Predicted GO |
BP | GO:0019318 | hexose metabolic process | IEP | Predicted GO |
BP | GO:0019319 | hexose biosynthetic process | IEP | Predicted GO |
MF | GO:0042578 | phosphoric ester hydrolase activity | IEP | Predicted GO |
MF | GO:0043169 | cation binding | IEP | Predicted GO |
BP | GO:0046364 | monosaccharide biosynthetic process | IEP | Predicted GO |
MF | GO:0046872 | metal ion binding | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001342 | HDH_cat | 2 | 130 |
No external refs found! |