MA_8849g0010

Description : (at3g13080 : 1497.0) encodes an ATP-dependent MRP-like ABC transporter able to transport glutathione-conjugates as well as chlorophyll catabolites. The expression of this gene is upregulated by herbicide safeners such as benoxacor and fenclorim.; multidrug resistance-associated protein 3 (MRP3); FUNCTIONS IN: chlorophyll catabolite transmembrane transporter activity, ATPase activity, coupled to transmembrane movement of substances, glutathione S-conjugate-exporting ATPase activity; INVOLVED IN: transport, transmembrane transport; LOCATED IN: apoplast, vacuolar membrane, plasma membrane, plant-type vacuole; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 8 (TAIR:AT3G13090.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (q6yuu5|mdr_orysa : 216.0) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 2994.0) & (original description: no original description)

Gene families : OG_42_0000076 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000076_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Picea release: MA_8849g0010
Cluster	HCCA clusters: Cluster_250

Target	Alias	Description	ECC score	Gene Family Method
169678	No alias	multidrug resistance-associated protein 6	0.02	Orthogroups_2024-Update
Bradi2g04577	No alias	multidrug resistance-associated protein 3	0.03	Orthogroups_2024-Update
Cre02.g103250	No alias	multidrug resistance-associated protein 2	0.01	Orthogroups_2024-Update
GRMZM2G111903	No alias	multidrug resistance-associated protein 14	0.02	Orthogroups_2024-Update
Glyma.08G190700	No alias	multidrug resistance-associated protein 6	0.02	Orthogroups_2024-Update
Glyma.10G019000	No alias	multidrug resistance-associated protein 4	0.02	Orthogroups_2024-Update
PSME_00023720-RA	No alias	(at1g30400 : 187.0) glutathione S-conjugate transporting...	0.03	Orthogroups_2024-Update
Potri.002G255800	No alias	multidrug resistance-associated protein 5	0.02	Orthogroups_2024-Update
Seita.5G163300.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Seita.7G043600.1	No alias	subfamily ABCC transporter	0.05	Orthogroups_2024-Update
Sobic.001G413000.2	No alias	subfamily ABCC transporter	0.03	Orthogroups_2024-Update
Sobic.006G021900.1	No alias	subfamily ABCC transporter	0.03	Orthogroups_2024-Update
Sobic.006G054200.1	No alias	subfamily ABCC transporter	0.03	Orthogroups_2024-Update
Sobic.010G066200.1	No alias	subfamily ABCC transporter	0.04	Orthogroups_2024-Update
Solyc08g006880	No alias	Multidrug resistance protein ABC transporter family...	0.03	Orthogroups_2024-Update
Solyc12g044820	No alias	ABC transporter-like family-protein (AHRD V3.3 ***...	0.03	Orthogroups_2024-Update
evm.model.contig_3396.7	No alias	(at2g34660 : 863.0) encodes a multidrug...	0.02	Orthogroups_2024-Update
evm.model.tig00000718.1	No alias	(at2g34660 : 358.0) encodes a multidrug...	0.01	Orthogroups_2024-Update
evm.model.tig00001254.7	No alias	(at2g47800 : 162.0) Encodes a plasma membrane localized...	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEA	InterProScan predictions
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000160	phosphorelay signal transduction system	IEP	Predicted GO
BP	GO:0000271	polysaccharide biosynthetic process	IEP	Predicted GO
MF	GO:0001871	pattern binding	IEP	Predicted GO
BP	GO:0009250	glucan biosynthetic process	IEP	Predicted GO
MF	GO:0015078	proton transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient	IEP	Predicted GO
BP	GO:0015991	ATP hydrolysis coupled proton transport	IEP	Predicted GO
CC	GO:0016020	membrane	IEP	Predicted GO
MF	GO:0016759	cellulose synthase activity	IEP	Predicted GO
MF	GO:0016760	cellulose synthase (UDP-forming) activity	IEP	Predicted GO
BP	GO:0030243	cellulose metabolic process	IEP	Predicted GO
BP	GO:0030244	cellulose biosynthetic process	IEP	Predicted GO
MF	GO:0030247	polysaccharide binding	IEP	Predicted GO
CC	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain	IEP	Predicted GO
CC	GO:0033179	proton-transporting V-type ATPase, V0 domain	IEP	Predicted GO
BP	GO:0033692	cellular polysaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0035556	intracellular signal transduction	IEP	Predicted GO
BP	GO:0051273	beta-glucan metabolic process	IEP	Predicted GO
BP	GO:0051274	beta-glucan biosynthetic process	IEP	Predicted GO
BP	GO:0090662	ATP hydrolysis coupled transmembrane transport	IEP	Predicted GO
BP	GO:0099131	ATP hydrolysis coupled ion transmembrane transport	IEP	Predicted GO
BP	GO:0099132	ATP hydrolysis coupled cation transmembrane transport	IEP	Predicted GO
BP	GO:1902600	proton transmembrane transport	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003439	ABC_transporter-like	1474	1622
IPR003439	ABC_transporter-like	830	962
IPR011527	ABC1_TM_dom	1140	1380
IPR011527	ABC1_TM_dom	586	762

External Links

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MA_8849g0010

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation