Description : (q8w013|comt1_catro : 164.0) Caffeic acid 3-O-methyltransferase (EC 2.1.1.68) (S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase) (COMT) (CAOMT) - Catharanthus roseus (Rosy periwinkle) (Madagascar periwinkle) & (at5g54160 : 156.0) A caffeic acid/5-hydroxyferulic acid O-methyltransferase. Interacts with 14-4-3 proteins in yeast 2 hybrid assay. AtOMT1 (At5g54160) encodes a flavonol 3Ã-O-methyltransferase that is highly active towards quercetin and myricetin. The substrate specificity identifies the enzyme as flavonol 3Ã-methyltransferase which replaces the former annotation of the gene to encode a caffeic acid/5-hydroxyferulic acid O-methyltransferase; O-methyltransferase 1 (OMT1); FUNCTIONS IN: myricetin 3'-O-methyltransferase activity, quercetin 3-O-methyltransferase activity, caffeate O-methyltransferase activity; INVOLVED IN: lignin biosynthetic process, flavonol biosynthetic process; LOCATED IN: cytosol, nucleus, plasma membrane, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase family protein (TAIR:AT1G77520.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 312.0) & (original description: no original description)
Gene families : OG_42_0000016 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000016_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_9153751g0010 | |
Cluster | HCCA clusters: Cluster_194 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
83100 | No alias | O-methyltransferase 1 | 0.02 | Orthogroups_2024-Update | |
Bradi1g22757 | No alias | O-methyltransferase family protein | 0.02 | Orthogroups_2024-Update | |
Brara.C01364.1 | No alias | caffeic acid O-methyltransferase *(COMT) & EC_2.1... | 0.03 | Orthogroups_2024-Update | |
Brara.H01339.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.05 | Orthogroups_2024-Update | |
Brara.H02296.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.04 | Orthogroups_2024-Update | |
Brara.J00896.1 | No alias | caffeic acid O-methyltransferase *(COMT) & EC_2.1... | 0.03 | Orthogroups_2024-Update | |
HORVU1Hr1G001570.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
HORVU6Hr1G092780.2 | No alias | EC_2.1 transferase transferring one-carbon group | 0.04 | Orthogroups_2024-Update | |
Kfl00158_0170 | kfl00158_0170_v1.... | (at5g54160 : 162.0) A caffeic acid/5-hydroxyferulic acid... | 0.02 | Orthogroups_2024-Update | |
LOC_Os09g17560 | No alias | O-methyltransferase, putative, expressed | 0.03 | Orthogroups_2024-Update | |
MA_10432299g0010 | No alias | (p45986|imt1_mescr : 130.0) Inositol 4-methyltransferase... | 0.04 | Orthogroups_2024-Update | |
PSME_00012623-RA | No alias | (q8w013|comt1_catro : 272.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
PSME_00013242-RA | No alias | (q8w013|comt1_catro : 208.0) Caffeic acid... | 0.03 | Orthogroups_2024-Update | |
PSME_00018014-RA | No alias | (q9fqy8|comt1_capan : 378.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
PSME_00021108-RA | No alias | (p28002|comt1_medsa : 130.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
PSME_00021109-RA | No alias | (q8w013|comt1_catro : 194.0) Caffeic acid... | 0.04 | Orthogroups_2024-Update | |
PSME_00032996-RA | No alias | (q8w013|comt1_catro : 410.0) Caffeic acid... | 0.06 | Orthogroups_2024-Update | |
PSME_00047714-RA | No alias | (q06509|comt1_maize : 221.0) Caffeic acid... | 0.02 | Orthogroups_2024-Update | |
PSME_00050591-RA | No alias | (q8w013|comt1_catro : 191.0) Caffeic acid... | 0.06 | Orthogroups_2024-Update | |
Seita.6G055900.1 | No alias | caffeic acid O-methyltransferase *(COMT) & EC_2.1... | 0.04 | Orthogroups_2024-Update | |
Seita.6G148100.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
Sobic.007G074800.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
Sobic.009G198000.1 | No alias | EC_2.1 transferase transferring one-carbon group | 0.03 | Orthogroups_2024-Update | |
Solyc10g047520 | No alias | LOW QUALITY:O-methyltransferase (AHRD V3.3 *-* Q6VMV7_MENPI) | 0.03 | Orthogroups_2024-Update | |
Sopen03g028450 | No alias | O-methyltransferase | 0.03 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0008171 | O-methyltransferase activity | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0001671 | ATPase activator activity | IEP | Predicted GO |
MF | GO:0004367 | glycerol-3-phosphate dehydrogenase [NAD+] activity | IEP | Predicted GO |
MF | GO:0004523 | RNA-DNA hybrid ribonuclease activity | IEP | Predicted GO |
MF | GO:0005524 | ATP binding | IEP | Predicted GO |
MF | GO:0008047 | enzyme activator activity | IEP | Predicted GO |
MF | GO:0008144 | drug binding | IEP | Predicted GO |
MF | GO:0015399 | primary active transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0015405 | P-P-bond-hydrolysis-driven transmembrane transporter activity | IEP | Predicted GO |
CC | GO:0016021 | integral component of membrane | IEP | Predicted GO |
MF | GO:0016462 | pyrophosphatase activity | IEP | Predicted GO |
MF | GO:0016787 | hydrolase activity | IEP | Predicted GO |
MF | GO:0016817 | hydrolase activity, acting on acid anhydrides | IEP | Predicted GO |
MF | GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | IEP | Predicted GO |
MF | GO:0016887 | ATPase activity | IEP | Predicted GO |
MF | GO:0017076 | purine nucleotide binding | IEP | Predicted GO |
MF | GO:0017111 | nucleoside-triphosphatase activity | IEP | Predicted GO |
MF | GO:0022804 | active transmembrane transporter activity | IEP | Predicted GO |
MF | GO:0030554 | adenyl nucleotide binding | IEP | Predicted GO |
CC | GO:0031224 | intrinsic component of membrane | IEP | Predicted GO |
MF | GO:0032553 | ribonucleotide binding | IEP | Predicted GO |
MF | GO:0032555 | purine ribonucleotide binding | IEP | Predicted GO |
MF | GO:0032559 | adenyl ribonucleotide binding | IEP | Predicted GO |
MF | GO:0035639 | purine ribonucleoside triphosphate binding | IEP | Predicted GO |
MF | GO:0042623 | ATPase activity, coupled | IEP | Predicted GO |
MF | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | IEP | Predicted GO |
MF | GO:0043492 | ATPase activity, coupled to movement of substances | IEP | Predicted GO |
CC | GO:0044425 | membrane part | IEP | Predicted GO |
MF | GO:0046983 | protein dimerization activity | IEP | Predicted GO |
MF | GO:0051087 | chaperone binding | IEP | Predicted GO |
MF | GO:0060589 | nucleoside-triphosphatase regulator activity | IEP | Predicted GO |
MF | GO:0060590 | ATPase regulator activity | IEP | Predicted GO |
MF | GO:0097367 | carbohydrate derivative binding | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR001077 | O_MeTrfase_2 | 14 | 118 |
No external refs found! |