Description : (at3g62980 : 514.0) Encodes an auxin receptor that mediates auxin-regulated transcription. It contains leucine-rich repeats and an F-box and interacts with ASK1, ASK2 and AtCUL1 to form SCF-TIR1, an SCF ubiquitin ligase complex. Related to yeast Grr1p and human SKP2 proteins, involved in ubiquitin-mediated processes. Required for normal response to auxin and repressed in response to flagellin. As part of the SCF complex and in the presence of auxin, TIR1 interacts with Aux/IAA transcriptional repressor proteins and mediates their degradation.; TRANSPORT INHIBITOR RESPONSE 1 (TIR1); CONTAINS InterPro DOMAIN/s: F-box domain, cyclin-like (InterPro:IPR001810), F-box domain, Skp2-like (InterPro:IPR022364); BEST Arabidopsis thaliana protein match is: GRR1-like protein 1 (TAIR:AT4G03190.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 1028.0) & (original description: no original description)
Gene families : OG_42_0000339 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000339_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_92309g0010 | |
Cluster | HCCA clusters: Cluster_211 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
At3g26810 | No alias | AFB2 [Source:UniProtKB/TrEMBL;Acc:A0A178VGF7] | 0.03 | Orthogroups_2024-Update | |
GRMZM2G079112 | No alias | RNI-like superfamily protein | 0.03 | Orthogroups_2024-Update | |
LOC_Os11g31620 | No alias | OsFBL55 - F-box domain and LRR containing protein, expressed | 0.02 | Orthogroups_2024-Update | |
MA_121693g0010 | No alias | (at5g49980 : 727.0) auxin F-box protein 5 (AFB5);... | 0.03 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003676 | nucleic acid binding | IEP | Predicted GO |
MF | GO:0003677 | DNA binding | IEP | Predicted GO |
MF | GO:0003700 | DNA-binding transcription factor activity | IEP | Predicted GO |
MF | GO:0003723 | RNA binding | IEP | Predicted GO |
MF | GO:0004672 | protein kinase activity | IEP | Predicted GO |
MF | GO:0005488 | binding | IEP | Predicted GO |
MF | GO:0005515 | protein binding | IEP | Predicted GO |
MF | GO:0005524 | ATP binding | IEP | Predicted GO |
BP | GO:0006139 | nucleobase-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0006355 | regulation of transcription, DNA-templated | IEP | Predicted GO |
BP | GO:0006396 | RNA processing | IEP | Predicted GO |
BP | GO:0006397 | mRNA processing | IEP | Predicted GO |
BP | GO:0006464 | cellular protein modification process | IEP | Predicted GO |
BP | GO:0006468 | protein phosphorylation | IEP | Predicted GO |
BP | GO:0006725 | cellular aromatic compound metabolic process | IEP | Predicted GO |
BP | GO:0006793 | phosphorus metabolic process | IEP | Predicted GO |
BP | GO:0006796 | phosphate-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0006807 | nitrogen compound metabolic process | IEP | Predicted GO |
MF | GO:0008144 | drug binding | IEP | Predicted GO |
BP | GO:0009889 | regulation of biosynthetic process | IEP | Predicted GO |
BP | GO:0010468 | regulation of gene expression | IEP | Predicted GO |
BP | GO:0010556 | regulation of macromolecule biosynthetic process | IEP | Predicted GO |
BP | GO:0016070 | RNA metabolic process | IEP | Predicted GO |
MF | GO:0016301 | kinase activity | IEP | Predicted GO |
BP | GO:0016310 | phosphorylation | IEP | Predicted GO |
MF | GO:0016772 | transferase activity, transferring phosphorus-containing groups | IEP | Predicted GO |
MF | GO:0016773 | phosphotransferase activity, alcohol group as acceptor | IEP | Predicted GO |
BP | GO:0019219 | regulation of nucleobase-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0019222 | regulation of metabolic process | IEP | Predicted GO |
BP | GO:0031123 | RNA 3'-end processing | IEP | Predicted GO |
BP | GO:0031124 | mRNA 3'-end processing | IEP | Predicted GO |
BP | GO:0031323 | regulation of cellular metabolic process | IEP | Predicted GO |
BP | GO:0031326 | regulation of cellular biosynthetic process | IEP | Predicted GO |
MF | GO:0035639 | purine ribonucleoside triphosphate binding | IEP | Predicted GO |
BP | GO:0036211 | protein modification process | IEP | Predicted GO |
MF | GO:0043015 | gamma-tubulin binding | IEP | Predicted GO |
BP | GO:0043170 | macromolecule metabolic process | IEP | Predicted GO |
BP | GO:0043412 | macromolecule modification | IEP | Predicted GO |
MF | GO:0043565 | sequence-specific DNA binding | IEP | Predicted GO |
BP | GO:0044237 | cellular metabolic process | IEP | Predicted GO |
BP | GO:0046483 | heterocycle metabolic process | IEP | Predicted GO |
BP | GO:0050789 | regulation of biological process | IEP | Predicted GO |
BP | GO:0050794 | regulation of cellular process | IEP | Predicted GO |
BP | GO:0051171 | regulation of nitrogen compound metabolic process | IEP | Predicted GO |
BP | GO:0051252 | regulation of RNA metabolic process | IEP | Predicted GO |
BP | GO:0060255 | regulation of macromolecule metabolic process | IEP | Predicted GO |
BP | GO:0065007 | biological regulation | IEP | Predicted GO |
BP | GO:0080090 | regulation of primary metabolic process | IEP | Predicted GO |
BP | GO:0090304 | nucleic acid metabolic process | IEP | Predicted GO |
MF | GO:0097159 | organic cyclic compound binding | IEP | Predicted GO |
MF | GO:0140110 | transcription regulator activity | IEP | Predicted GO |
MF | GO:1901363 | heterocyclic compound binding | IEP | Predicted GO |
BP | GO:1903506 | regulation of nucleic acid-templated transcription | IEP | Predicted GO |
BP | GO:2000112 | regulation of cellular macromolecule biosynthetic process | IEP | Predicted GO |
BP | GO:2001141 | regulation of RNA biosynthetic process | IEP | Predicted GO |
No InterPro domains available for this sequence
No external refs found! |