MA_9379473g0010


Description : (p35063|h2ax_picab : 189.0) Histone H2AX - Picea abies (Norway spruce) (Picea excelsa) & (at1g54690 : 184.0) Encodes HTA3, a histone H2A protein. H2AX is a meiosis-specific isoform of histone H2A. Upon DSB formation, rapid accumulation of phosphorylated H2AX (γ-H2AX) occurs around the break site. H2AX foci accumulate in early G2. Immunolocalization studies in spread preparations of wild-type meiocytes at G2/early leptotene revealed the accumulation of numerous rather diffuse γ-H2AX foci throughout the chromatin. However, their accumulation is not contemporaneous with that of AtSPO11-1. At 3 h post-S, no γ-H2AX foci are detected. During the 3- to 5-h window when AtSPO11-1 foci rapidly disappear, there is an equally swift accumulation of γ-H2AX to a maximum of >50 diffuse foci. The level of γH2AX then remains constant for a further 13 h before undergoing a gradual decrease to 10ñ20 foci in the 18- to 24-h post-S period. By 30 h the foci have disappeared from the chromatin.; gamma histone variant H2AX (GAMMA-H2AX); FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleolus, nucleus; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: Histone superfamily protein (TAIR:AT1G08880.1); Has 3932 Blast hits to 3927 proteins in 364 species: Archae - 0; Bacteria - 0; Metazoa - 2549; Fungi - 335; Plants - 612; Viruses - 4; Other Eukaryotes - 432 (source: NCBI BLink). & (reliability: 368.0) & (original description: no original description)


Gene families : OG_42_0000138 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000138_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_9379473g0010
Cluster HCCA clusters: Cluster_115

Target Alias Description ECC score Gene Family Method Actions
Bradi1g66370 No alias histone H2A 6 0.02 Orthogroups_2024-Update
GRMZM2G151726 No alias histone H2A 2 0.03 Orthogroups_2024-Update
Glyma.15G040300 No alias histone H2A 12 0.03 Orthogroups_2024-Update
HORVU6Hr1G006140.1 No alias histone *(H2A) 0.06 Orthogroups_2024-Update
HORVU6Hr1G092390.1 No alias histone *(H2A) 0.03 Orthogroups_2024-Update
PSME_00021426-RA No alias (p40280|h2a_maize : 125.0) Histone H2A - Zea mays... 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
CC GO:0000786 nucleosome IEA InterProScan predictions
MF GO:0003677 DNA binding IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0002682 regulation of immune system process IEP Predicted GO
BP GO:0002831 regulation of response to biotic stimulus IEP Predicted GO
CC GO:0005783 endoplasmic reticulum IEP Predicted GO
BP GO:0010112 regulation of systemic acquired resistance IEP Predicted GO
MF GO:0020037 heme binding IEP Predicted GO
BP GO:0031347 regulation of defense response IEP Predicted GO
BP GO:0032101 regulation of response to external stimulus IEP Predicted GO
BP GO:0043900 regulation of multi-organism process IEP Predicted GO
BP GO:0045088 regulation of innate immune response IEP Predicted GO
MF GO:0046906 tetrapyrrole binding IEP Predicted GO
BP GO:0048583 regulation of response to stimulus IEP Predicted GO
BP GO:0050776 regulation of immune response IEP Predicted GO
BP GO:0080134 regulation of response to stress IEP Predicted GO
InterPro domains Description Start Stop
IPR032454 Histone_H2A_C 103 136
IPR007125 Histone_H2A/H2B/H3 23 100
No external refs found!