Description : (p35063|h2ax_picab : 189.0) Histone H2AX - Picea abies (Norway spruce) (Picea excelsa) & (at1g54690 : 184.0) Encodes HTA3, a histone H2A protein. H2AX is a meiosis-specific isoform of histone H2A. Upon DSB formation, rapid accumulation of phosphorylated H2AX (γ-H2AX) occurs around the break site. H2AX foci accumulate in early G2. Immunolocalization studies in spread preparations of wild-type meiocytes at G2/early leptotene revealed the accumulation of numerous rather diffuse γ-H2AX foci throughout the chromatin. However, their accumulation is not contemporaneous with that of AtSPO11-1. At 3 h post-S, no γ-H2AX foci are detected. During the 3- to 5-h window when AtSPO11-1 foci rapidly disappear, there is an equally swift accumulation of γ-H2AX to a maximum of >50 diffuse foci. The level of γH2AX then remains constant for a further 13 h before undergoing a gradual decrease to 10ñ20 foci in the 18- to 24-h post-S period. By 30 h the foci have disappeared from the chromatin.; gamma histone variant H2AX (GAMMA-H2AX); FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleolus, nucleus; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: Histone superfamily protein (TAIR:AT1G08880.1); Has 3932 Blast hits to 3927 proteins in 364 species: Archae - 0; Bacteria - 0; Metazoa - 2549; Fungi - 335; Plants - 612; Viruses - 4; Other Eukaryotes - 432 (source: NCBI BLink). & (reliability: 368.0) & (original description: no original description)
Gene families : OG_42_0000138 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000138_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Picea release: MA_9379473g0010 | |
Cluster | HCCA clusters: Cluster_115 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Bradi1g66370 | No alias | histone H2A 6 | 0.02 | Orthogroups_2024-Update | |
GRMZM2G151726 | No alias | histone H2A 2 | 0.03 | Orthogroups_2024-Update | |
Glyma.15G040300 | No alias | histone H2A 12 | 0.03 | Orthogroups_2024-Update | |
HORVU6Hr1G006140.1 | No alias | histone *(H2A) | 0.06 | Orthogroups_2024-Update | |
HORVU6Hr1G092390.1 | No alias | histone *(H2A) | 0.03 | Orthogroups_2024-Update | |
PSME_00021426-RA | No alias | (p40280|h2a_maize : 125.0) Histone H2A - Zea mays... | 0.03 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
CC | GO:0000786 | nucleosome | IEA | InterProScan predictions |
MF | GO:0003677 | DNA binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0002682 | regulation of immune system process | IEP | Predicted GO |
BP | GO:0002831 | regulation of response to biotic stimulus | IEP | Predicted GO |
CC | GO:0005783 | endoplasmic reticulum | IEP | Predicted GO |
BP | GO:0010112 | regulation of systemic acquired resistance | IEP | Predicted GO |
MF | GO:0020037 | heme binding | IEP | Predicted GO |
BP | GO:0031347 | regulation of defense response | IEP | Predicted GO |
BP | GO:0032101 | regulation of response to external stimulus | IEP | Predicted GO |
BP | GO:0043900 | regulation of multi-organism process | IEP | Predicted GO |
BP | GO:0045088 | regulation of innate immune response | IEP | Predicted GO |
MF | GO:0046906 | tetrapyrrole binding | IEP | Predicted GO |
BP | GO:0048583 | regulation of response to stimulus | IEP | Predicted GO |
BP | GO:0050776 | regulation of immune response | IEP | Predicted GO |
BP | GO:0080134 | regulation of response to stress | IEP | Predicted GO |
No external refs found! |