MA_96750g0010


Description : (at3g50660 : 574.0) Encodes a 22α hydroxylase whose reaction is a rate-limiting step in brassinosteroid biosynthetic pathway. The protein is a member of CYP90B gene family. CLM is an epi-allele with small, compressed rosette, reduced internode length, and reduced fertility, appears in selfed ddm mutant plants possibly due to loss of cytosine methylation. Transcripts accumulate in actively growing tissues, and GUS expression is negatively regulated by brassinosteroids. Localized in the endoplasmic reticulum. The in vitro expressed protein can perform the C-22 hydroxylation of a variety of C27-, C28- and C29-sterols. Cholesterol was the best substrate, followed by campesterol. Sitosterol was a poor substrate.; DWARF 4 (DWF4); CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, conserved site (InterPro:IPR017972), Cytochrome P450, E-class, group I (InterPro:IPR002401); BEST Arabidopsis thaliana protein match is: Cytochrome P450 superfamily protein (TAIR:AT5G05690.1); Has 31120 Blast hits to 31036 proteins in 1650 species: Archae - 61; Bacteria - 5303; Metazoa - 10591; Fungi - 5722; Plants - 7996; Viruses - 3; Other Eukaryotes - 1444 (source: NCBI BLink). & (q6f4f5|c724b_orysa : 434.0) Cytochrome P450 724B1 (EC 1.14.-.-) (OsDWARF11) (Dwarf protein 11) - Oryza sativa (Rice) & (reliability: 1148.0) & (original description: no original description)


Gene families : OG_42_0000020 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000020_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_96750g0010
Cluster HCCA clusters: Cluster_206

Target Alias Description ECC score Gene Family Method Actions
Brara.A01028.1 No alias abscisic acid hydroxylase & EC_1.14 oxidoreductase... 0.03 Orthogroups_2024-Update
GRMZM2G103773 No alias brassinosteroid-6-oxidase 2 0.02 Orthogroups_2024-Update
GRMZM2G161169 No alias cytochrome P450, family 716, subfamily A, polypeptide 1 0.02 Orthogroups_2024-Update
Glyma.02G057500 No alias Cytochrome P450 superfamily protein 0.03 Orthogroups_2024-Update
HORVU2Hr1G011170.2 No alias EC_1.14 oxidoreductase acting on paired donor with... 0.03 Orthogroups_2024-Update
Mp3g17510.1 No alias Abscisic acid 8-hydroxylase 4 OS=Arabidopsis thaliana... 0.02 Orthogroups_2024-Update
Potri.009G064900 No alias cytochrome P450, family 87, subfamily A, polypeptide 2 0.02 Orthogroups_2024-Update
Potri.011G001300 No alias cytochrome P450, family 716, subfamily A, polypeptide 1 0.02 Orthogroups_2024-Update
Potri.018G134000 No alias cytochrome P450, family 716, subfamily A, polypeptide 1 0.02 Orthogroups_2024-Update
Potri.018G135100 No alias cytochrome P450, family 716, subfamily A, polypeptide 1 0.02 Orthogroups_2024-Update
Solyc04g078900 No alias ABA 8'-hydroxylase 0.03 Orthogroups_2024-Update
Sopen08g003800 No alias Cytochrome P450 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005506 iron ion binding IEA InterProScan predictions
MF GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA InterProScan predictions
MF GO:0020037 heme binding IEA InterProScan predictions
BP GO:0055114 oxidation-reduction process IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0006633 fatty acid biosynthetic process IEP Predicted GO
MF GO:0015035 protein disulfide oxidoreductase activity IEP Predicted GO
MF GO:0015036 disulfide oxidoreductase activity IEP Predicted GO
MF GO:0016667 oxidoreductase activity, acting on a sulfur group of donors IEP Predicted GO
BP GO:0030163 protein catabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR001128 Cyt_P450 87 499
No external refs found!