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  5. MA_97664g0010

MA_97664g0010


Description : (at4g22970 : 81.6) Encodes a separase (ESP), homologous to human and mouse separase protein. Separase is a capase family protease required for the release of sister chromatid cohesion during meiosis and mitosis. Arabidopsis separase contains a predicted 2Fe2S-ferredoxin domain that is not present in the proteins of other organisms. Also contains a putative EF-hand calcium binding domain. Mutant seeds exhibited embryo arrest at the globular stage. The endosperm also exhibited a weak titan-like phenotype. Transgenic plants expressing AESP RNA interference (RNAi) from the meiosis-specific DMC1 promoter exhibited alterations in chromosome segregation during meiosis I and II that resulted in polyads containing from one to eight microspores. Plays an essential role in embryo development. Required for the removal of cohesin from meiotic chromosomes and establishment of meiotic nuclear domains. This gene was also identified through the rsw4 mutant. Lines carrying recessive, temperature-sensitive mutations exhibit reduced anisotropic growth at 30 degrees Celsius. Microtubules and cellulose microfibrils are not depleted or disoriented in the mutants at the restrictive temperature.; homolog of separase (ESP); FUNCTIONS IN: peptidase activity; INVOLVED IN: meiotic chromosome separation, chromosome separation, embryo development ending in seed dormancy, positive regulation of sister chromatid cohesion, endosperm development; LOCATED IN: nucleus; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase C50, separase (InterPro:IPR005314); BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT5G28550.1). & (reliability: 163.2) & (original description: no original description)


Gene families : OG_42_0004157 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004157_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Picea release: MA_97664g0010
Cluster HCCA clusters: Cluster_104

Target Alias Description ECC score Gene Family Method Actions
At5g28550 No alias BEST Arabidopsis thaliana protein match is: homolog of... 0.04 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source
MF GO:0003774 motor activity IEP Predicted GO
MF GO:0003777 microtubule motor activity IEP Predicted GO
MF GO:0004611 phosphoenolpyruvate carboxykinase activity IEP Predicted GO
MF GO:0004612 phosphoenolpyruvate carboxykinase (ATP) activity IEP Predicted GO
BP GO:0005996 monosaccharide metabolic process IEP Predicted GO
BP GO:0006006 glucose metabolic process IEP Predicted GO
BP GO:0006094 gluconeogenesis IEP Predicted GO
BP GO:0006928 movement of cell or subcellular component IEP Predicted GO
BP GO:0007017 microtubule-based process IEP Predicted GO
BP GO:0007018 microtubule-based movement IEP Predicted GO
MF GO:0008017 microtubule binding IEP Predicted GO
MF GO:0015631 tubulin binding IEP Predicted GO
MF GO:0016830 carbon-carbon lyase activity IEP Predicted GO
MF GO:0016831 carboxy-lyase activity IEP Predicted GO
BP GO:0019318 hexose metabolic process IEP Predicted GO
BP GO:0019319 hexose biosynthetic process IEP Predicted GO
BP GO:0046364 monosaccharide biosynthetic process IEP Predicted GO
MF GO:0051287 NAD binding IEP Predicted GO

No InterPro domains available for this sequence

No external refs found!