evm.model.contig_2050.3


Description : (at5g26780 : 637.0) Encodes a protein with serine hydroxymethyltransferase activity which is thought to be localized in the mitochondrial matrix. SHM2 expression fails to rescue the conditional lethal phenotype of the shm1-1 mutant, defective in SHM1.; serine hydroxymethyltransferase 2 (SHM2); FUNCTIONS IN: glycine hydroxymethyltransferase activity, cobalt ion binding, zinc ion binding; INVOLVED IN: glycine metabolic process, L-serine metabolic process; LOCATED IN: mitochondrion, mitochondrial respiratory chain complex I; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Serine hydroxymethyltransferase, pyridoxal phosphate binding site (InterPro:IPR019798), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Serine hydroxymethyltransferase (InterPro:IPR001085); BEST Arabidopsis thaliana protein match is: serine transhydroxymethyltransferase 1 (TAIR:AT4G37930.1); Has 11562 Blast hits to 11539 proteins in 2821 species: Archae - 258; Bacteria - 6362; Metazoa - 333; Fungi - 287; Plants - 321; Viruses - 6; Other Eukaryotes - 3995 (source: NCBI BLink). & (p50433|glym_soltu : 634.0) Serine hydroxymethyltransferase, mitochondrial precursor (EC 2.1.2.1) (Serine methylase) (Glycine hydroxymethyltransferase) (SHMT) - Solanum tuberosum (Potato) & (reliability: 1154.0) & (original description: no original description)


Gene families : OG_42_0000626 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000626_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_2050.3
Cluster HCCA clusters: Cluster_28

Target Alias Description ECC score Gene Family Method Actions
A4A49_22571 No alias serine hydroxymethyltransferase 3, chloroplastic 0.01 Orthogroups_2024-Update
A4A49_25960 No alias serine hydroxymethyltransferase, mitochondrial 0.02 Orthogroups_2024-Update
Brara.A00108.1 No alias serine hydroxymethyltransferase *(SHM) & serine... 0.02 Orthogroups_2024-Update
Brara.H01745.1 No alias serine hydroxymethyltransferase & EC_2.1 transferase... 0.02 Orthogroups_2024-Update
Glyma.08G274400 No alias serine transhydroxymethyltransferase 1 0.01 Orthogroups_2024-Update
Glyma.18G150000 No alias serine transhydroxymethyltransferase 1 0.02 Orthogroups_2024-Update
Kfl00359_0090 kfl00359_0090_v1.1 (p34899|glym_pea : 701.0) Serine... 0.02 Orthogroups_2024-Update
PSME_00015002-RA No alias (p49358|glyn_flapr : 512.0) Serine... 0.02 Orthogroups_2024-Update
Pp1s21_270V6 No alias glycine hydroxymethyltransferase 0.03 Orthogroups_2024-Update
Sobic.001G097100.3 No alias serine hydroxymethyltransferase *(SHM) & serine... 0.01 Orthogroups_2024-Update
Solyc02g091560 No alias Serine hydroxymethyltransferase (AHRD V3.3 *** A0A0R4J3Y9_SOYBN) 0.03 Orthogroups_2024-Update
Sopen02g036190 No alias Serine hydroxymethyltransferase 0.02 Orthogroups_2024-Update
evm.model.tig00001130.31 No alias (at4g13930 : 555.0) Encodes a serine... 0.04 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
BP GO:0001505 regulation of neurotransmitter levels IEP Predicted GO
MF GO:0003824 catalytic activity IEP Predicted GO
MF GO:0004089 carbonate dehydratase activity IEP Predicted GO
MF GO:0004177 aminopeptidase activity IEP Predicted GO
MF GO:0004325 ferrochelatase activity IEP Predicted GO
MF GO:0004329 formate-tetrahydrofolate ligase activity IEP Predicted GO
MF GO:0004375 glycine dehydrogenase (decarboxylating) activity IEP Predicted GO
BP GO:0006544 glycine metabolic process IEP Predicted GO
BP GO:0006546 glycine catabolic process IEP Predicted GO
BP GO:0006779 porphyrin-containing compound biosynthetic process IEP Predicted GO
BP GO:0006783 heme biosynthetic process IEP Predicted GO
BP GO:0006855 drug transmembrane transport IEP Predicted GO
MF GO:0008081 phosphoric diester hydrolase activity IEP Predicted GO
BP GO:0009063 cellular amino acid catabolic process IEP Predicted GO
BP GO:0009069 serine family amino acid metabolic process IEP Predicted GO
BP GO:0009071 serine family amino acid catabolic process IEP Predicted GO
BP GO:0015893 drug transport IEP Predicted GO
BP GO:0016054 organic acid catabolic process IEP Predicted GO
CC GO:0016272 prefoldin complex IEP Predicted GO
MF GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors IEP Predicted GO
MF GO:0016642 oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor IEP Predicted GO
MF GO:0016829 lyase activity IEP Predicted GO
MF GO:0016835 carbon-oxygen lyase activity IEP Predicted GO
MF GO:0016836 hydro-lyase activity IEP Predicted GO
BP GO:0042133 neurotransmitter metabolic process IEP Predicted GO
BP GO:0042135 neurotransmitter catabolic process IEP Predicted GO
BP GO:0042168 heme metabolic process IEP Predicted GO
BP GO:0042737 drug catabolic process IEP Predicted GO
BP GO:0044282 small molecule catabolic process IEP Predicted GO
BP GO:0046148 pigment biosynthetic process IEP Predicted GO
BP GO:0046395 carboxylic acid catabolic process IEP Predicted GO
MF GO:0048037 cofactor binding IEP Predicted GO
MF GO:0050662 coenzyme binding IEP Predicted GO
BP GO:1901606 alpha-amino acid catabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR039429 SHMT-like_dom 49 448
No external refs found!