Description : (at3g06483 : 292.0) Pyruvate dehydrogenase kinase (PDK) specifically phosphorylates the E1α subunit of the pyruvate dehydrogenase complex (PDC) on a Ser residue using ATP as a phosphate donor. PDK is a unique type of protein kinase having a His-kinase-like sequence but Ser-kinase activity. Site-directed mutagenesis and structural analysis indicate that PDK belongs to the GHKL superfamily.; pyruvate dehydrogenase kinase (PDK); FUNCTIONS IN: ATP binding, pyruvate dehydrogenase (acetyl-transferring) kinase activity, histidine phosphotransfer kinase activity; INVOLVED IN: signal transduction, peptidyl-histidine phosphorylation, phosphorylation; LOCATED IN: mitochondrion; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Signal transduction histidine kinase, core (InterPro:IPR005467), Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, mitochondrial (InterPro:IPR018955), ATPase-like, ATP-binding domain (InterPro:IPR003594), Signal transduction histidine kinase-related protein, C-terminal (InterPro:IPR004358); Has 1925 Blast hits to 1799 proteins in 531 species: Archae - 0; Bacteria - 712; Metazoa - 467; Fungi - 468; Plants - 102; Viruses - 0; Other Eukaryotes - 176 (source: NCBI BLink). & (reliability: 584.0) & (original description: no original description)
Gene families : OG_42_0003838 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003838_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Porphyridium release: evm.model.contig_2057.12 | |
Cluster | HCCA clusters: Cluster_43 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004180 | carboxypeptidase activity | IEP | Predicted GO |
MF | GO:0004181 | metallocarboxypeptidase activity | IEP | Predicted GO |
MF | GO:0004252 | serine-type endopeptidase activity | IEP | Predicted GO |
MF | GO:0008081 | phosphoric diester hydrolase activity | IEP | Predicted GO |
MF | GO:0008235 | metalloexopeptidase activity | IEP | Predicted GO |
MF | GO:0008236 | serine-type peptidase activity | IEP | Predicted GO |
MF | GO:0017171 | serine hydrolase activity | IEP | Predicted GO |
BP | GO:0120009 | intermembrane lipid transfer | IEP | Predicted GO |
MF | GO:0120013 | intermembrane lipid transfer activity | IEP | Predicted GO |
MF | GO:0140096 | catalytic activity, acting on a protein | IEP | Predicted GO |
No external refs found! |