evm.model.contig_2057.12


Description : (at3g06483 : 292.0) Pyruvate dehydrogenase kinase (PDK) specifically phosphorylates the E1α subunit of the pyruvate dehydrogenase complex (PDC) on a Ser residue using ATP as a phosphate donor. PDK is a unique type of protein kinase having a His-kinase-like sequence but Ser-kinase activity. Site-directed mutagenesis and structural analysis indicate that PDK belongs to the GHKL superfamily.; pyruvate dehydrogenase kinase (PDK); FUNCTIONS IN: ATP binding, pyruvate dehydrogenase (acetyl-transferring) kinase activity, histidine phosphotransfer kinase activity; INVOLVED IN: signal transduction, peptidyl-histidine phosphorylation, phosphorylation; LOCATED IN: mitochondrion; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Signal transduction histidine kinase, core (InterPro:IPR005467), Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, mitochondrial (InterPro:IPR018955), ATPase-like, ATP-binding domain (InterPro:IPR003594), Signal transduction histidine kinase-related protein, C-terminal (InterPro:IPR004358); Has 1925 Blast hits to 1799 proteins in 531 species: Archae - 0; Bacteria - 712; Metazoa - 467; Fungi - 468; Plants - 102; Viruses - 0; Other Eukaryotes - 176 (source: NCBI BLink). & (reliability: 584.0) & (original description: no original description)


Gene families : OG_42_0003838 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003838_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_2057.12
Cluster HCCA clusters: Cluster_43


Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
MF GO:0004180 carboxypeptidase activity IEP Predicted GO
MF GO:0004181 metallocarboxypeptidase activity IEP Predicted GO
MF GO:0004252 serine-type endopeptidase activity IEP Predicted GO
MF GO:0008081 phosphoric diester hydrolase activity IEP Predicted GO
MF GO:0008235 metalloexopeptidase activity IEP Predicted GO
MF GO:0008236 serine-type peptidase activity IEP Predicted GO
MF GO:0017171 serine hydrolase activity IEP Predicted GO
BP GO:0120009 intermembrane lipid transfer IEP Predicted GO
MF GO:0120013 intermembrane lipid transfer activity IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
InterPro domains Description Start Stop
IPR018955 BCDHK/PDK_N 75 231
IPR003594 HATPase_C 283 413
No external refs found!