evm.model.contig_2177.3


Description : (at4g34640 : 311.0) Encodes squalene synthase, which converts two molecules of farnesyl diphosphate (FPP) into squalene via an intermediate: presqualene diphosphate (PSPP). It is generally thought to be one of the key enzymes of sterol biosynthesis, since it catalyzes the first pathway-specific reaction of the sterol branch of the isoprenoid pathway.; squalene synthase 1 (SQS1); FUNCTIONS IN: farnesyl-diphosphate farnesyltransferase activity; INVOLVED IN: sterol biosynthetic process; LOCATED IN: endoplasmic reticulum, plasma membrane, endoplasmic reticulum membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Squalene/phytoene synthase, conserved site (InterPro:IPR019845), Terpenoid synthase (InterPro:IPR008949), Farnesyl-diphosphate farnesyltransferase (InterPro:IPR006449), Squalene/phytoene synthase (InterPro:IPR002060); BEST Arabidopsis thaliana protein match is: squalene synthase 2 (TAIR:AT4G34650.1); Has 1469 Blast hits to 1468 proteins in 521 species: Archae - 28; Bacteria - 581; Metazoa - 114; Fungi - 174; Plants - 415; Viruses - 0; Other Eukaryotes - 157 (source: NCBI BLink). & (reliability: 622.0) & (original description: no original description)


Gene families : OG_42_0003316 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003316_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Porphyridium release: evm.model.contig_2177.3
Cluster HCCA clusters: Cluster_50

Target Alias Description ECC score Gene Family Method Actions
Glyma.11G112000 No alias squalene synthase 1 0.02 Orthogroups_2024-Update
Pp1s23_185V6 No alias squalene synthase 0.02 Orthogroups_2024-Update
Solyc01g110290 No alias Squalene synthase (AHRD V3.3 *** D0VFU8_SOLLC) 0.03 Orthogroups_2024-Update
Sopen01g052440 No alias Squalene/phytoene synthase 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
BP GO:0000272 polysaccharide catabolic process IEP Predicted GO
MF GO:0003674 molecular_function IEP Predicted GO
MF GO:0003746 translation elongation factor activity IEP Predicted GO
MF GO:0003824 catalytic activity IEP Predicted GO
MF GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity IEP Predicted GO
MF GO:0004478 methionine adenosyltransferase activity IEP Predicted GO
MF GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEP Predicted GO
MF GO:0004618 phosphoglycerate kinase activity IEP Predicted GO
MF GO:0005506 iron ion binding IEP Predicted GO
MF GO:0005548 phospholipid transporter activity IEP Predicted GO
CC GO:0005852 eukaryotic translation initiation factor 3 complex IEP Predicted GO
BP GO:0005975 carbohydrate metabolic process IEP Predicted GO
BP GO:0005976 polysaccharide metabolic process IEP Predicted GO
BP GO:0006090 pyruvate metabolic process IEP Predicted GO
BP GO:0006414 translational elongation IEP Predicted GO
BP GO:0006486 protein glycosylation IEP Predicted GO
BP GO:0006556 S-adenosylmethionine biosynthetic process IEP Predicted GO
BP GO:0006629 lipid metabolic process IEP Predicted GO
MF GO:0008135 translation factor activity, RNA binding IEP Predicted GO
BP GO:0008610 lipid biosynthetic process IEP Predicted GO
BP GO:0009240 isopentenyl diphosphate biosynthetic process IEP Predicted GO
BP GO:0015748 organophosphate ester transport IEP Predicted GO
BP GO:0015914 phospholipid transport IEP Predicted GO
BP GO:0016052 carbohydrate catabolic process IEP Predicted GO
MF GO:0016160 amylase activity IEP Predicted GO
MF GO:0016161 beta-amylase activity IEP Predicted GO
MF GO:0016229 steroid dehydrogenase activity IEP Predicted GO
CC GO:0016272 prefoldin complex IEP Predicted GO
MF GO:0016491 oxidoreductase activity IEP Predicted GO
MF GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEP Predicted GO
MF GO:0016725 oxidoreductase activity, acting on CH or CH2 groups IEP Predicted GO
MF GO:0016726 oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016746 transferase activity, transferring acyl groups IEP Predicted GO
MF GO:0016774 phosphotransferase activity, carboxyl group as acceptor IEP Predicted GO
MF GO:0016798 hydrolase activity, acting on glycosyl bonds IEP Predicted GO
MF GO:0016854 racemase and epimerase activity IEP Predicted GO
MF GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives IEP Predicted GO
BP GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway IEP Predicted GO
MF GO:0020037 heme binding IEP Predicted GO
MF GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0043169 cation binding IEP Predicted GO
BP GO:0043413 macromolecule glycosylation IEP Predicted GO
BP GO:0046490 isopentenyl diphosphate metabolic process IEP Predicted GO
BP GO:0046500 S-adenosylmethionine metabolic process IEP Predicted GO
MF GO:0046906 tetrapyrrole binding IEP Predicted GO
MF GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer IEP Predicted GO
BP GO:0050992 dimethylallyl diphosphate biosynthetic process IEP Predicted GO
BP GO:0050993 dimethylallyl diphosphate metabolic process IEP Predicted GO
MF GO:0051745 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
BP GO:0070085 glycosylation IEP Predicted GO
MF GO:0070569 uridylyltransferase activity IEP Predicted GO

No InterPro domains available for this sequence

No external refs found!