Description : (at4g34640 : 311.0) Encodes squalene synthase, which converts two molecules of farnesyl diphosphate (FPP) into squalene via an intermediate: presqualene diphosphate (PSPP). It is generally thought to be one of the key enzymes of sterol biosynthesis, since it catalyzes the first pathway-specific reaction of the sterol branch of the isoprenoid pathway.; squalene synthase 1 (SQS1); FUNCTIONS IN: farnesyl-diphosphate farnesyltransferase activity; INVOLVED IN: sterol biosynthetic process; LOCATED IN: endoplasmic reticulum, plasma membrane, endoplasmic reticulum membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Squalene/phytoene synthase, conserved site (InterPro:IPR019845), Terpenoid synthase (InterPro:IPR008949), Farnesyl-diphosphate farnesyltransferase (InterPro:IPR006449), Squalene/phytoene synthase (InterPro:IPR002060); BEST Arabidopsis thaliana protein match is: squalene synthase 2 (TAIR:AT4G34650.1); Has 1469 Blast hits to 1468 proteins in 521 species: Archae - 28; Bacteria - 581; Metazoa - 114; Fungi - 174; Plants - 415; Viruses - 0; Other Eukaryotes - 157 (source: NCBI BLink). & (reliability: 622.0) & (original description: no original description)
Gene families : OG_42_0003316 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003316_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Porphyridium release: evm.model.contig_2177.3 | |
Cluster | HCCA clusters: Cluster_50 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Glyma.11G112000 | No alias | squalene synthase 1 | 0.02 | Orthogroups_2024-Update | |
Pp1s23_185V6 | No alias | squalene synthase | 0.02 | Orthogroups_2024-Update | |
Solyc01g110290 | No alias | Squalene synthase (AHRD V3.3 *** D0VFU8_SOLLC) | 0.03 | Orthogroups_2024-Update | |
Sopen01g052440 | No alias | Squalene/phytoene synthase | 0.03 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No GO annotation available for this sequence |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0000272 | polysaccharide catabolic process | IEP | Predicted GO |
MF | GO:0003674 | molecular_function | IEP | Predicted GO |
MF | GO:0003746 | translation elongation factor activity | IEP | Predicted GO |
MF | GO:0003824 | catalytic activity | IEP | Predicted GO |
MF | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity | IEP | Predicted GO |
MF | GO:0004478 | methionine adenosyltransferase activity | IEP | Predicted GO |
MF | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds | IEP | Predicted GO |
MF | GO:0004618 | phosphoglycerate kinase activity | IEP | Predicted GO |
MF | GO:0005506 | iron ion binding | IEP | Predicted GO |
MF | GO:0005548 | phospholipid transporter activity | IEP | Predicted GO |
CC | GO:0005852 | eukaryotic translation initiation factor 3 complex | IEP | Predicted GO |
BP | GO:0005975 | carbohydrate metabolic process | IEP | Predicted GO |
BP | GO:0005976 | polysaccharide metabolic process | IEP | Predicted GO |
BP | GO:0006090 | pyruvate metabolic process | IEP | Predicted GO |
BP | GO:0006414 | translational elongation | IEP | Predicted GO |
BP | GO:0006486 | protein glycosylation | IEP | Predicted GO |
BP | GO:0006556 | S-adenosylmethionine biosynthetic process | IEP | Predicted GO |
BP | GO:0006629 | lipid metabolic process | IEP | Predicted GO |
MF | GO:0008135 | translation factor activity, RNA binding | IEP | Predicted GO |
BP | GO:0008610 | lipid biosynthetic process | IEP | Predicted GO |
BP | GO:0009240 | isopentenyl diphosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0015748 | organophosphate ester transport | IEP | Predicted GO |
BP | GO:0015914 | phospholipid transport | IEP | Predicted GO |
BP | GO:0016052 | carbohydrate catabolic process | IEP | Predicted GO |
MF | GO:0016160 | amylase activity | IEP | Predicted GO |
MF | GO:0016161 | beta-amylase activity | IEP | Predicted GO |
MF | GO:0016229 | steroid dehydrogenase activity | IEP | Predicted GO |
CC | GO:0016272 | prefoldin complex | IEP | Predicted GO |
MF | GO:0016491 | oxidoreductase activity | IEP | Predicted GO |
MF | GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | IEP | Predicted GO |
MF | GO:0016725 | oxidoreductase activity, acting on CH or CH2 groups | IEP | Predicted GO |
MF | GO:0016726 | oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor | IEP | Predicted GO |
MF | GO:0016746 | transferase activity, transferring acyl groups | IEP | Predicted GO |
MF | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor | IEP | Predicted GO |
MF | GO:0016798 | hydrolase activity, acting on glycosyl bonds | IEP | Predicted GO |
MF | GO:0016854 | racemase and epimerase activity | IEP | Predicted GO |
MF | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives | IEP | Predicted GO |
BP | GO:0019288 | isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway | IEP | Predicted GO |
MF | GO:0020037 | heme binding | IEP | Predicted GO |
MF | GO:0033764 | steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | IEP | Predicted GO |
MF | GO:0043169 | cation binding | IEP | Predicted GO |
BP | GO:0043413 | macromolecule glycosylation | IEP | Predicted GO |
BP | GO:0046490 | isopentenyl diphosphate metabolic process | IEP | Predicted GO |
BP | GO:0046500 | S-adenosylmethionine metabolic process | IEP | Predicted GO |
MF | GO:0046906 | tetrapyrrole binding | IEP | Predicted GO |
MF | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer | IEP | Predicted GO |
BP | GO:0050992 | dimethylallyl diphosphate biosynthetic process | IEP | Predicted GO |
BP | GO:0050993 | dimethylallyl diphosphate metabolic process | IEP | Predicted GO |
MF | GO:0051745 | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity | IEP | Predicted GO |
BP | GO:0055114 | oxidation-reduction process | IEP | Predicted GO |
BP | GO:0070085 | glycosylation | IEP | Predicted GO |
MF | GO:0070569 | uridylyltransferase activity | IEP | Predicted GO |
No InterPro domains available for this sequence
No external refs found! |